Professor Lesley Rhodes BSc, MD, FRCP, FRSB

Photograph of Lesley Rhodes

Professor of Experimental Dermatology

Institute of Inflammation and Repair
University of Manchester
Photobiology Unit, Dermatology Centre
Salford Royal Foundation Trust
Manchester, M6 8HD
UK

Institute of Inflammation and Repair website
Salford Royal NHS Foundation Trust website

Role

Professor of Experimental Dermatology, Honorary Consultant Dermatologist, Director of the Photobiology Unit.

Memberships of Committees and Professional Bodies

Current:

  • President, European Society for Photobiology
  • Board, Advisory Group on Non-Ionising Radiation, Public Health England
  • NICE Public Health Advisory Committee: Sunlight exposures: benefits & risks
  • Cancer Research UK, Skin Cancer Prevention Advisory Board
  • Board, USA Photomedicine Society
  • Emeritus Editor, Photodermatology Photoimmunology Photomedicine
  • Scientific Advisory Board, International Photodynamic Association
  • Member of British Association of Dermatologists, British Photodermatology Group, British Society of Investigative Dermatology, European Society for Dermatological Research, European Academy of Dermatovenereology, European Platform for Photodynamic Medicine, American Society for Photobiology, International Fellow of the American Academy of Dermatology, USA Photomedicine Society, International Photodynamic Association.

 Previous:

  • Lead for Epidemiology, Education and Prevention, NCRI Melanoma Clinical Studies Group
  • President-Elect, European Society for Photobiology
  • Secretary, European Society for Photobiology
  • Chair, UK Skin Cancer Working Party
  • Chair, British Photodermatology Group
  • Committee, British Society for Investigative Dermatology
  • Associate Editor, Photochemical & Photobiological Sciences
  • Co-Editor, Photodermatology, Photoimmunology, Photomedicine

 

Research

  • Ultraviolet and visible light effects on healthy and diseased skin particularly photosensitivity disorders (sun allergies), mechanisms of acute inflammatory responses, relationships to longer term damage and means for protection and repair.
  • Cutaneous nutrient-ultraviolet interaction, sunlight and vitamin D synthesis.
  • Photodynamic therapy.

Methodological Knowledge

  • Human studies, nutritional studies, photobiology studies
  • Cutaneous iontophoresis, tissue sampling including microdialysis
  • Ultraviolet dose-response modelling
  • In vivo and in vitro irradiation, fluorescence spectroscopy
  • Immunohistochemistry, cell culture, applications of mass spectroscopy

Teaching

  • Development of electronic dermatology undergraduate education
  • Undergraduate Education Academic Advisor
  • Postgraduate degree supervisor
  • Educational Supervisor - research project options

Biography

Lesley Rhodes is Professor of Experimental Dermatology, Director of the Photobiology Unit and Honorary Consultant Dermatologist at the University of Manchester and Salford Royal Hospital , Manchester.  Current appointments include President, European Society for Photobiology; Board member, NICE Public Health Advisory Committee: Sunlight exposures: benefits & risks; Board member, Public Health England (Advisory Group on Non-Ionising Radiation); Emeritus Editor Photoderm, Photoimmunol, Photomed; Board of the USA Photomedicine Society.  Previously Lead for Epidemiology, Education and Prevention, NCRI Melanoma Clinical Studies Group; Leader, Dermatological Sciences Research Group, University of Manchester; Chair, UK Skin Cancer Working Party; Chair, British Photodermatology Group and Associate Editor, Photochem Photobiol Sci.  She obtained her medical degree in London and her clinical and research training in Dermatology at the Royal Liverpool University Hospitals and University of Liverpool, and the Wellman Laboratories of Photomedicine, Boston, USA. She runs a supra-regional diagnostic service in photosensitivity disorders and  photodynamic therapy for skin cancer treatment. Her research programme focuses on the mechanisms of visible and ultraviolet radiation effects on the skin, including inflammation, vitamin D synthesis, photodynamic therapy, photosensitivity disorders and the development of photoprotection including dietary and hormonal measures. She has >150 publications with >110 original manuscripts and >40 commentaries, reviews and book chapters.  Research funding includes BBSRC, Cancer Research UK, Association for International Cancer Research, The Wellcome Trust, Department of Health and the European Union.

Qualifications

BSc 1st Class Honours. Basic Medical Sciences/Physical Anthropology, University College, London

AKC Associateship of Kings College, Kings College, London

MB BS Kings College London & Kings College Hospital Medical School

MD "Mechanisms of UVB-induced erythema", University of Liverpool

FRCP (UK )

FRSB

Collaborators and affiliated staff

Ann Webb, Jacqueline Berry, Anna Nicolaou, Adele Green, Gary Williamson, Zulf Mughal, Judith Adams, Tony Thody, Desmond Tobin, Gillian Ashcroft, Chris Griffiths, Neil Gibbs, Rachel Watson, Mark Birch-Machin, Frank de Gruijl, Peter Friedmann, Helen Richards etc.

Selected publications

2016

  • Black, H., & Rhodes, L. E. (2016). Potential Benefits of Omega-3 Fatty Acids in Non-Melanoma Skin Cancer. Journal of Clinical Medicine, 5(2), [23]. . Publication link: 1d2c8fa8-56a1-40b9-9941-d72e576ada81
  • Clarke, K. A., Dew, T. P., Watson, R., Farrar, M. D., Osman, J., Nicolaou, A., ... Williamson, G. (2016). Green tea catechins and their metabolites in human skin before and after exposure to ultraviolet radiation.The Journal of Nutritional Biochemistry, 27(1), 203-210. DOI:doi:10.1016/j.jnutbio.2015.09.001. Publication link: f05e765c-ee23-4ddf-af9e-e481a9affe0e
  • Ling, T. C., Clayton, T. H., Crawley, J., Exton, L. S., Goulden, V., Ibbotson, S., ... Dawe, R. S. (2016). British Association of Dermatologists and British Photodermatology Group guidelines for the safe and effective use of PUVA therapy 2016.British Journal of Dermatology, 174(1), 24-55. . Publication link: e7a6171b-afe8-4d52-87c2-010b83c71f05

2015

  • Kazantzidis, A., Smedley, A. R. D., Kift, R. C., Rimmer, J. S., Berry, J. L., Rhodes, L. E., & Webb, A. R. (2015). A modeling approach to determine how much UV radiation is available across the UK and Ireland for health risk and benefit studies. Photochemical & Photobiological Sciences, 14(1073), 1073-1081. DOI:10.1039/c5pp00008d. Publication link: 520b83ab-a6fd-46f9-b84b-8bc0bd10e758
  • Rhodes, L. E., Gould, S. M., Farrar, M. D., Kift, R., Berry, J. L., Mughal, M. Z., ... Webb, A. R. (2015). Sunlight exposure and photoprotection behaviour of white Caucasian adolescents in the UK. European Academy of Dermatology and Venereology. Journal, 29(4), 732-737. . Publication link: ab6810e6-11cc-4fc9-9091-9d4891598648
  • Rhodes, L. E., Kendall, A. C., Pilkington, S. M., Massey, K. A., Sassano, G., & Nicolaou, A. (2015). Distribution of bioactive lipid mediators in human skin. The Journal of Investigative Dermatology, 135, 1510-1520. . Publication link: 9dd1c628-a2a0-4cfa-8e31-d347ac1b91a7
  • Rhodes, L. E., Langendonk, J. G., Balwani, M., Anderson, K. E., Bonkovsky, H. L., Anstey, A. V., ... Desnick, R. J. (2015). Afamelanotide for Erythropoietic Protoporphyria. New England Journal of Medicine, 373(1), 48-59. DOI:10.1056/NEJMoa1411481. Publication link: 8a437c3c-1014-4d11-a590-b919e1b35390
  • Rhodes, L. E., Pilkington, S. M., Murphy, S. A., Kudva, S., & Nicolaou, A. (2015). COX inhibition reduces vasodilator PGE2 but is shown to increase levels of chemoattractant 12-HETE in vivo in human sunburn. EXPERIMENTAL DERMATOLOGY, 24, 790-791. . Publication link: e46c8934-0810-47ed-b251-d8e01d39d2f4
  • Rhodes, L. E., Shih, B., Allan, D., & de, G. F. R. (2015). Robust detection of minimal sunburn in pigmented skin by 785 nm laser speckle contrast imaging of blood flux. The Journal of Investigative Dermatology, 135(4), 1197-1199. . Publication link: d843e049-57be-4a4d-9439-c3cad408652a

2014

  • Haylett, A. K., Chiang, Y. Z., Nie, Z., Ling, T. C., & Rhodes, L. E. (2014). Sunscreen photopatch testing: A series of 157 children. British Journal of Dermatology. DOI:10.1111/bjd.13003. Publication link: f890738c-1213-444b-b53c-41a63f33ab76 | PubMed:24673302
  • Pilkington, S. M., Gibbs, N. K., Friedmann, P. S., & Rhodes, L. E. (2014). Nutritional abrogation of photoimmunosuppression: In vivo investigations. Photodermatology Photoimmunology and Photomedicine, 30(2-3), 112-127. DOI:10.1111/phpp.12091. Publication link: 263f1b11-0aa4-4f2f-a104-c1da63147b69 | PubMed:24283330
  • Pilkington, S. M., Rhodes, L. E., Al-Aasswad, N. M. I., Massey, K. A., & Nicolaou, A. (2014). Impact of EPA ingestion on COX- and LOX-mediated eicosanoid synthesis in skin with and without a pro-inflammatory UVR challenge - Report of a randomised controlled study in humans. Molecular Nutrition and Food Research, 58(3), 580-590. DOI:10.1002/mnfr.201300405. Publication link: bf8d1069-a195-45fa-b29b-8b342ab05c4e | PubMed:24311515
  • Rhodes, L. E., Webb, A. R., Berry, J. L., Felton, S. J., Marjanovic, E. J., Wilkinson, J. D., ... Kift, R. (2014). Sunlight exposure behaviour and vitamin D status in photosensitive patients: longitudinal comparative study with healthy individuals at UK latitude.British Journal of Dermatology, 171(6), 1478-1486. . Publication link: d86f16f2-7de8-4a88-ad6b-8196a5403367
  • Rhodes, L., Mills, S., Farrar, M., Ashcroft, G., Griffiths, C., Hardman, M., & L, . U. (2014). Topical PDT following excisional wounding of human skin increases production of TGF-β3, MMP-1 and MMP-9 with associated improvement in dermal matrix organisation. British Journal of Dermatology, 171, 55-62. . Publication link: e7373d9f-1514-42c6-9066-6ffd15cc32e5

2013

  • Brooke, R., Sidhu, M., Sinha, A., Watson, R., Friedmann, P., Clough, G., & Rhodes, L. E. (2013). Prostaglandin E2 and nitric oxide mediate the acute inflammatory (erythemal) response to topical 5-aminolevulinic acid-photodynamic therapy in human skin. Br J Dermatol, 169, 645-652. . Publication link: 1ecb849d-c9c4-4b93-a442-eff9923522a8
  • Farrar, M. D., Webb, A. R., Kift, R., Durkin, M., Allan, D., Herbert, A., ... Rhodes, L. E. (2013). Efficacy of a dose range of simulated sunlight exposures in raising vitamin D status in South Asian adults: Implications for targeted guidance on sun exposure. American Journal of Clinical Nutrition, 97(6), 1210-1216. DOI:10.3945/ajcn.112.052639. Publication link: 29cf2c55-97b6-4141-bb49-dcab013da25b | PubMed:23615828
  • Felton, S., Navid, F., Schwarz, A., Schwarz, T., Gläser, R., & Rhodes, L. E. (2013). Ultraviolet radiation-induced upregulation of antimicrobial proteins in health and disease. Photochemical and Photobiological Sciences, 12(1), 29-36. DOI:10.1039/c2pp25158b. Publication link: 49db534f-a32a-4841-b3a5-28f9234cb29e
  • Gonçalo, M., Ferguson, J., Bonevalle, A., Bruynzeel, D. P., Giménez-Arnau, A., Goossens, A., ... Wilkinson, M. (2013). Photopatch testing: Recommendations for a European photopatch test baseline series. Contact Dermatitis, 68(4), 239-243. DOI:10.1111/cod.12037. Publication link: 6bf82a3f-fe7a-4251-8710-99399e1bd64a
  • Haylett, A. K., Felton, S., Denning, D. W., & Rhodes, L. E. (2013). Voriconazole-induced photosensitivity: Photobiological assessment of a case series of 12 patients. British Journal of Dermatology, 168(1), 179-185. DOI:10.1111/j.1365-2133.2012.11196.x. Publication link: edffa516-ed91-4e38-a860-89504bec7b3a | PubMed:22860570
  • Morley, S., Griffiths, J., Philips, G., Moseley, H., O’Grady, C., Mellish, K., ... Rhodes, L. E. (2013). Phase IIa randomised, placebo-controlled study of antimicrobial photodynamic therapy in bacterially colonised, chronic leg ulcers and diabetic foot ulcers. A new approach to antimicrobial therapy.British Journal of Dermatology, 168, 617-624. . Publication link: 49b15846-4c55-40fe-a2df-6155150d6dc5
  • Pilkington, S. M., Massey, K. A., Bennett, S. P., Al-Aasswad, N. M. I., Roshdy, K., Gibbs, N. K., ... Rhodes, L. E. (2013). A randomised controlled trial of oral omega-3 PUFA in solar simulated radiation-induced suppression of human cutaneous immune responses. American Journal Of Clinical Nutrition, 97, 646-652. . Publication link: eda8bf73-7a75-49f9-9d45-dcee8187a84a
  • Rhodes, L. E., Darby, G., Massey, K. A., Clarke, K. A., Dew, T. P., Farrar, M. D., ... Nicolaou, A. (2013). Oral green tea catechin metabolites are incorporated into human skin and protect against UVR-induced cutaneous inflammation in association with reduced production of pro-inflammatory eicosanoid 12-HETE. British Journal of Nutrition, 110, 891-900. . Publication link: 1b959df4-7552-40d5-a028-31457a6038b2
  • Rhodes, L. E., Kift, R., Berry, J. L., Vail, A., Durkin, M. T., & Webb, A. R. (2013). Lifestyle factors including less cutaneous sun exposure contribute to starkly lower vitamin D status in UK South Asians compared to the white Caucasian population.British Journal of Dermatology, 169(6), 1272-1278. . Publication link: cc111249-6bfe-47fb-af5e-e0cb4d864df6
  • Rizwan, M., Reddick, C. L., Bundy, C., Unsworth, R., Richards, H. L., & Rhodes, L. E. (2013). Photodermatoses: Environmentally induced conditions with high psychological impact. Photochemical and Photobiological Sciences, 12(1), 182-189. DOI:10.1039/c2pp25177a. Publication link: 451220ec-14ef-441f-bcc3-7b11202fcfaf
  • Wallingford, S. C., Pilkington, S. M., Massey, K. A., Al-Aasswad, N. M. I., Ibiebele, T. I., Hughes, M. C., ... Green, A. C. (2013). Three-way assessment of long chain omega-3 polyunsaturated fatty acid nutrition: by questionnaire and matched blood and skin samples.British Journal of Nutrition, 109, 701-708. DOI:10.1017/S0007114512001997. Publication link: fdbe04a8-84ea-4ccb-899c-f9ce51ca07cb

2012

2011

2010

  • Gledhill, K., Rhodes, L. E., Brownrigg, M., Haylett, A. K., Masoodi, M., Thody, A. J., ... Tobin, D. J. (2010). Prostaglandin-E2 is produced by adult human epidermal melanocytes in response to UVB in a melanogenesis-independent manner. Pigment Cell and Melanoma Research, 23(3), 394-403. DOI:10.1111/j.1755-148X.2010.00696.x. Publication link: bc4998bf-847e-450f-97c0-3c2544bfd78c | PubMed:20236442
  • Langan, E. A., Nie, Z., & Rhodes, L. E. (2010). Melanotropic peptides: More than just 'Barbie drugs' and 'sun-tan jabs'?. British Journal of Dermatology, 163(3), 451-455. DOI:10.1111/j.1365-2133.2010.09891.x. Publication link: cc37c75c-2387-4f4d-8f33-7476a27b1752
  • Masoodi, M., Nicolaou, A., Gledhill, K., Rhodes, L. E., Tobin, D. J., & Thody, A. J. (2010). Prostaglandin D2 production in FM55 melanoma cells is regulated by α-melanocyte-stimulating hormone and is not related to melanin production. Experimental Dermatology, 19(8), 751-753. DOI:10.1111/j.1600-0625.2010.01098.x. Publication link: 5da0163f-8b47-4915-ba2d-8a33a2feca25
  • Nie, Z., Bayat, A., Behzad, F., & Rhodes, L. E. (2010). Positive response of a recurrent keloid scar to topical methyl aminolevulinate-photodynamic therapy. Photodermatology Photoimmunology and Photomedicine, 26(6), 330-332. DOI:10.1111/j.1600-0781.2010.00539.x. Publication link: 842aca6c-32fa-4dba-94b4-70b91d3844b3 | PubMed:21140993
  • Rhodes, L. E., Bock, M., Janssens, A. S., Ling, T. C., Anastasopoulou, L., Antoniou, C., ... Diepgen, T. L. (2010). Polymorphic light eruption occurs in 18% of europeans and does not show higher prevalence with increasing latitude: Multicenter survey of 6,895 individuals residing from the mediterranean to scandinavia. Journal of Investigative Dermatology, 130(2), 626-628. DOI:10.1038/jid.2009.250. Publication link: bc92d475-9218-457b-9aeb-99b82eb02f7e
  • Rhodes, L. E., Webb, A. R., Fraser, H. I., Kift, R., Durkin, M. T., Allan, D., ... Berry, J. L. (2010). Recommended summer sunlight exposure levels can produce sufficient (≥20 ng ml-1) but Not the Proposed Optimal (≥32 ng ml-1) 25(OH)D levels at UK latitudes. Journal of Investigative Dermatology, 130(5), 1411-1418. DOI:10.1038/jid.2009.417. Publication link: 617d1a15-cdbf-4573-aa24-a269e415b0ac | PubMed:20072137
  • Stafford, R., Farrar, M. D., Kift, R., Durkin, M., Berry, J. L., Webb, A. R., & Rhodes, L. E. (2010). The impact of photosensitivity disorders on aspects of lifestyle. British Journal of Dermatology, 163(4), 817-822. DOI:10.1111/j.1365-2133.2010.09905.x. Publication link: bffdd39c-90b0-4b02-9057-d00a70cd3525 | PubMed:20545692
  • Webb, A. R., Kift, R., Durkin, M. T., OBrien, S. J., Vail, A., Berry, J. L., ... O'Brien, S. (2010). The role of sunlight exposure in determining the vitamin D status of the U.K. white adult population. British Journal of Dermatology, 163(5), 1050-1055. DOI:10.1111/j.1365-2133.2010.09975.x. Publication link: 8c4e6231-9dba-4166-aa7a-f93c5aae3ccd | PubMed:20716215

2009

  • Rhodes, L. E., Gledhill, K., Masoodi, M., Haylett, A. K., Brownrigg, M., Thody, A. J., ... Nicolaou, A. (2009). The sunburn response in human skin is characterized by sequential eicosanoid profiles that may mediate its early and late phases. FASEB Journal, 23(11), 3947-3956. DOI:10.1096/fj.09-136077. Publication link: a547e426-ca99-4c6e-9a03-d79b6576afa9 | PubMed:19584301
  • Rutter, K. J., Watson, R. E. B., Cotterell, L. F., Brenn, T., Griffiths, C. E. M., & Rhodes, L. E. (2009). Severely photosensitive psoriasis: A phenotypically defined patient subset. Journal of Investigative Dermatology, 129(12), 2861-2867. DOI:10.1038/jid.2009.156. Publication link: a6dc5a75-fbc6-4f88-9203-5dab014d19e1 | PubMed:19536141
  • Langan, E. A., Ramlogan, D., Jamieson, L. A., & Rhodes, L. E. (2009). Change in moles linked to use of unlicensed "sun tan jab". BMJ, 338(7689), 251. DOI:10.1136/bmj.b277. Publication link: 1c3fa22e-46b9-4cf5-ae80-cb7d72d11e3e

2008

  • Jong, C. T., Finlay, A. Y., Pearse, A. D., Kerr, A. C., Ferguson, J., Benton, E. C., ... Anstey, A. V. (2008). The quality of life of 790 patients with photodermatoses. British Journal of Dermatology, 159(1), 192-197. DOI:10.1111/j.1365-2133.2008.08581.x. Publication link: d4fe2fac-8cfd-4d9e-aec8-9368f1488b53
  • Kaufmann, R., Spelman, L., Weightman, W., Reifenberger, J., Szeimies, R. M., Verhaeghe, E., ... Rhodes, L. E. (2008). Multicentre intraindividual randomized trial of topical methyl aminolaevulinate-photodynamic therapy vs. cryotherapy for multiple actinic keratoses on the extremities. British Journal of Dermatology, 158(5), 994-999. DOI:10.1111/j.1365-2133.2008.08488.x. Publication link: 0b4c402b-4441-43f3-9196-7d592182a3e2
  • Rhodes, L. E., Morton, C. A., & McKenna, K. E. (2008). Guidelines for Topical Photodynamic Therapy: Update. On behalf of the British Association of Dermatologists Therapy Guidelines and Audit Subcommittee and the British Photodermatology Group.British Journal of Dermatology, 159. . Publication link: 644ece62-d4e7-4f4a-871e-6028cda72cdb
  • Richards, H. L., Ling, T. C., Evangelou, G., Brooke, R. C. C., Fortune, D. G., & Rhodes, L. E. (2008). Evidence of high levels of anxiety and depression in polymorphic light eruption and their association with clinical and demographic variables. British Journal of Dermatology, 159(2), 439-444. DOI:10.1111/j.1365-2133.2008.08623.x. Publication link: b8a5e057-5b0f-457d-8f46-2f142dca5337
  • Saraceno, R., Nisticò, S. P., Capriotti, E., De Felice, C., Rhodes, L. E., & Chimenti, S. (2008). Monochromatic excimer light (308 nm) in the treatment of prurigo nodularis. Photodermatology Photoimmunology and Photomedicine, 24(1), 43-45. DOI:10.1111/j.1600-0781.2008.00318.x. Publication link: 7f897cbc-e606-4e6f-a2e5-3492e2df4b30
  • Yesudian, P. D., Berry, J. L., Wiles, S., Hoyle, S., Young, D. B., Haylett, A. K., ... Davies, P. (2008). The effect of ultraviolet B-induced vitamin D levels on host resistance to Mycobacterium tuberculosis: A pilot study in immigrant Asian adults living in the United Kingdom. Photodermatology Photoimmunology and Photomedicine, 24(2), 97-98. DOI:10.1111/j.1600-0781.2008.00339.x. Publication link: bd7f8d40-8a7d-43c4-86c9-2a4deb1f0ac3

2007

  • Harries, M. J., Street, G., Gilmour, E., Rhodes, L. E., & Beck, M. H. (2007). Allergic contact dermatitis to methyl aminolevulinate (Metvix®) cream used in photodynamic therapy. Photodermatology Photoimmunology and Photomedicine, 23(1), 35-36. DOI:10.1111/j.1600-0781.2007.00270.x. Publication link: faf3e31b-20bc-4ac2-9f63-a7adb3b542e7
  • Janssens, A. S., Pavel, S., Ling, T., Winhoven, S. M., Anastasopoulou, N., Stratigos, A., ... Rhodes, L. E. (2007). Susceptibility to UV-A and UV-B provocation does not correlate with disease severity of polymorphic light eruption. Archives of Dermatology, 143(5), 599-604. DOI:10.1001/archderm.143.5.599. Publication link: 0e3e812e-247c-4483-97c1-ad8dd5e4d715
  • Rhodes, L., Rhodes, L. E., De Rie, M. A., Leifsdottir, R., Yu, R. C., Bachmann, I., ... Wolf, P. (2007). Five-year follow-up of a randomized, prospective trial of topical methyl aminolevulinate photodynamic therapy vs surgery for nodular basal cell carcinoma. Archives of Dermatology, 143(9), 1131-1136. DOI:10.1001/archderm.143.9.1131. Publication link: 9b2bc1b2-a414-4317-a325-afa888724a73
  • Storey, A., Rogers, J. S., McArdle, F., Jackson, M. J., & Rhodes, L. E. (2007). Conjugated linoleic acids modulate UVR-induced IL-8 and PGE2 in human skin cells: Potential of CLA isomers in nutritional photoprotection. Carcinogenesis, 28(6), 1329-1333. DOI:10.1093/carcin/bgm065. Publication link: 4d031088-3a96-4c77-a7a3-0b3b3f5d30d6

2006

  • Brooke, R. C. C., Sinha, A., Sidhu, M. K., Watson, R. E. B., Church, M. K., Friedmann, P. S., ... Rhodes, L. E. (2006). Histamine is released following aminolevulinic acid-photodynamic therapy of human skin and mediates an aminolevulinic acid dose-related immediate inflammatory response. Journal of Investigative Dermatology, 126(10), 2296-2301. DOI:10.1038/sj.jid.5700449. Publication link: bd003ecb-aebc-4819-9481-74ab157ab98a
  • Bryden, A. M., Moseley, H., Ibbotson, S. H., Chowdhury, M. M. U., Beck, M. H., Bourke, J., ... Ferguson, J. (2006). Photopatch testing of 1155 patients: Results of the U.K. multicentre photopatch study group. British Journal of Dermatology, 155(4), 737-747. DOI:10.1111/j.1365-2133.2006.07458.x. Publication link: 05b7ba78-0f07-4ccc-83cb-827a369fe1a4
  • Farrimond, H., Dornan, T. L., Cockcroft, A., & Rhodes, L. E. (2006). Development and evaluation of an e-learning package for teaching skin examination. Action research. British Journal of Dermatology, 155(3), 592-599. DOI:10.1111/j.1365-2133.2006.07360.x. Publication link: dbfcd255-12e4-4e01-b7c9-dbe5ea7d728c
  • Ling, T. C., Richards, H. L., Janssens, A. S., Anastassopoulou, L., Antoniou, C., Aubin, F., ... Rhodes, L. E. (2006). Seasonal and latitudinal impact of polymorphic light eruption on quality of life [1]. Journal of Investigative Dermatology, 126(7), 1648-1651. DOI:10.1038/sj.jid.5700306. Publication link: 9ba6d78e-6030-4747-b22e-63cba22cdbef
  • McKenna, K. E., Whittaker, S., Rhodes, L. E., Taylor, P., Lloyd, J., Ibbotson, S., & Russell-Jones, R. (2006). Evidence-based practice of photopheresis 1987-2001: A report of a workshop of the British Photodermatology Group and the U.K. Skin Lymphoma Group. British Journal of Dermatology, 154(1), 7-20. DOI:10.1111/j.1365-2133.2005.06857.x. Publication link: 665593f1-b686-4faa-a532-50d72221e5b2

2005

2004

  • Ibbotson, S. H., Bilsland, D., Cox, N. H., Dawe, R. S., Diffey, B., Edwards, C., ... Taylor, D. K. (2004). An update and guidance on narrowband ultraviolet B phototherapy: A British Photodermatology Group Workshop Report. British Journal of Dermatology, 151(2), 283-297. DOI:10.1111/j.1365-2133.2004.06128.x. Publication link: 1fc8c3b6-2ca5-4a34-93e8-67a81fccff9c
  • Rhodes, L. E., McArdle, F., Parslew, R., Jack, C., Friedmann, P., & Jackson, M. (2004). Effects of oral vitamin E and b-carotene supplementation on UVR-induced oxidative stress in human skin.Am J Clin Nutr, 80(5). . Publication link: 44da7562-982f-4a53-a83a-70ffb499cd7e
  • Rhodes, L., Rhodes, L. E., De Rie, M., Enström, Y., Groves, R., Morken, T., ... Wolf, P. (2004). Photodynamic Therapy Using Topical Methyl Aminolevulinate vs Surgery for Nodular Basal Cell Carcinoma: Results of a Multicenter Randomized Prospective Trial. Archives of Dermatology, 140(1), 17-23. DOI:10.1001/archderm.140.1.17. Publication link: 5de5ac6f-07ad-4a2a-90d5-5c1778825aad
  • Shahbakhti, H., Watson, R. E. B., Azurdia, R. M., Ferreira, C. Z., Garmyn, M., & Rhodes, L. E. (2004). Influence of eicosapentaenoic acid, an omega-3 fatty acid, on ultraviolet-B generation of prostaglandin-E2 and proinflammatory cytokines interleukin-1β, tumor necrosis factor-α, interleukin-6 and interleukin-8 in human skin in vivo. Photochemistry and Photobiology, 80(2), 231-235. DOI:10.1562/2004-01-27-RA-066.1. Publication link: 3284e826-800d-4b86-adfa-e5d11034deb2

2003

  • Horn, M., Wolf, P., Wulf, H. C., Warloe, T., Fritsch, C., Rhodes, L. E., ... Larkö, O. (2003). Topical methyl aminolaevulinate photodynamic therapy in patients with basal cell carcinoma prone to complications and poor cosmetic outcome with conventional treatment. British Journal of Dermatology, 149(6), 1242-1249. DOI:10.1111/j.1365-2133.2003.05600.x. Publication link: e783b5f0-08af-428b-b754-221bec2ebaab
  • Ling, T. C., Faulkner, C., & Rhodes, L. E. (2003). A questionnaire survey of attitudes to and usage of sunscreens in northwest England. Photodermatology Photoimmunology and Photomedicine, 19(2), 98-101. DOI:10.1034/j.1600-0781.2003.00026.x. Publication link: 3aba1048-0977-44d2-82b5-eca0993858b2
  • Rhodes, L., Choudry, K., Brooke, R. C. C., & Farrar, W. (2003). The effect of an iron chelating agent on protoporphyrin IX levels and phototoxicity in topical ALA-PDT.British Journal of Dermatology, 149 (1), 124-130. . Publication link: d17c1f84-a7cc-41fd-abc1-2e075d693990
  • Rhodes, L., Rhodes, L. E., Shahbakhti, H., Azurdia, R. M., Moison, R. M. W., Steenwinkel, M. J. S. T., ... Vink, A. A. (2003). Effect of eicosapentaenoic acid, an omega-3 polyunsaturated fatty acid, on UVR-related cancer risk in humans. An assessment of early genotoxic markers. Carcinogenesis, 24(5), 919-925. DOI:10.1093/carcin/bgg038. Publication link: 4156e9ba-0de1-4f27-8adf-f19e99323d9e

2002

  • Morton, C. A., Brown, S. B., Collins, S., Ibbotson, S., Jenkinson, H., Kurwa, H., ... Rhodes, L. E. (2002). Guidelines for topical photodynamic therapy: Report of a workshop of the British Photodermatology Group. British Journal of Dermatology, 146(4), 552-567. DOI:10.1046/j.1365-2133.2002.04719.x. Publication link: 7f46aa22-d0b2-4eb7-911c-f1b37cf62867
  • Pupe, A., Moison, R., De Haes, P., Van Henegouwen, G. B., Rhodes, L., Degreef, H., & Garmyn, M. (2002). Eicosapentaenoic acid, a n-3 polyunsaturated fatty acid differentially modulates TNF-α, IL-1α, IL-6 and PGE2 expression in UVB-irradiated human keratinocytes. Journal of Investigative Dermatology, 118(4), 692-698. DOI:10.1046/j.1523-1747.2002.01615.x. Publication link: 89f64cd4-7d1e-4876-8c2d-21cb8ef450d6
  • Rhodes, L. E., Jackson, M. J., McArdle, F., Storey, A., & McArdle, A. (2002). Effects of micronutrient supplements on UV-induced skin damage. Proceedings of the Nutrition Society, 61 (2), 187-9. . Publication link: d44206d9-14bb-4e73-a9f4-eabd0a98bb62
  • Rhodes, L. E., McArdle, F., Parslew, R., Jack, C. I. A., Friedmann, P. S., & Jackson, M. J. (2002). UVR-induced oxidative stress in human skin in vivo: Effects of vitamin C supplementation.Free Radical Biological Medicine, 33 (10), 1355-1362. . Publication link: 8b2d35f5-3639-42bd-a52c-406bc6569b3b
  • Taylor, D. K., Anstey, A. V., Coleman, A. J., Diffey, B. L., Farr, P. M., Ferguson, J., ... Rogers, S. (2002). Guidelines for dosimetry and calibration in ultraviolet radiation therapy: A report of a British Photodermatology Group Workshop. British Journal of Dermatology, 146(5), 755-763. DOI:10.1046/j.1365-2133.2002.04740.x. Publication link: 6f82d775-8937-4167-9112-601e1b46cb01

2001

  • Azurdia, R. M., Anstey, A. V., & Rhodes, L. E. (2001). Cholesterol supplementation objectively reduces photosensitivity in the Smith-Lemli-Opitz syndrome. British Journal of Dermatology, 144(1), 143-145. DOI:10.1046/j.1365-2133.2001.03964.x. Publication link: d6b803e7-0abe-4744-99d8-2387421bd7de
  • Rhodes, L. E., Belgi, G., Parslew, R., McLoughlin, L., Clough, G. F., & Friedmann, P. S. (2001). UVB-induced erythema is mediated by nitric oxide and PGE2 in combination.Journal of Investigative dermatology, 117 (4), 880-885. . Publication link: f7bdcbe8-d74e-4740-ab6f-5c5597aa3f08
  • Rhodes, L. E., Gerscher, S., Connelly, J. P., Beinersbergen, V. H. G. M. J., MacRobert, A. J., & Watt, P. (2001). A quantitative comparison of protoporphyrin IX pharmacokinetics and phototoxicity in human skin following iontophoretic delivery of the pro-drugs 5-aminolevulinic acid and 5-aminolevulinic-n-pentylester. British Journal of Dermatology, 144 (5), 983-990. . Publication link: 0625d33a-0cbd-4b12-bb89-0716a2e95d90

2000

  • Bell, H. K., & Rhodes, L. E. (2000). Photopatch testing in photosensitive patients [23]. British Journal of Dermatology, 142(3), 589-590. DOI:10.1046/j.1365-2133.2000.03401.x. Publication link: f17c84ad-372a-4a95-9117-2b46205d1fbb
  • Halpern, S. M., Anstey, A. V., Dawe, R. S., Diffey, B. L., Farr, P. M., Ferguson, J., ... Rhodes, L. E. (2000). Guidelines for topical PUVA: A report of a workshop of the British Photodermatology Group. British Journal of Dermatology, 142(1), 22-31. DOI:10.1046/j.1365-2133.2000.03237.x. Publication link: 9522cc4a-d44b-4cdf-a25c-6cb8019b08d2
  • Rhodes, L. E., Azurdia, R. M., & Pagliaro, J. (2000). Sunscreeen application technique in photosensitive patients: a quantitative assessment of the effect of education. Photodermatol Photoimmunol Photomed, 16 (2), 53-56. . Publication link: 89c4711e-05cb-424f-93c3-c6f589ed92d6
  • Rhodes, L. E., Gerscher, S., Connelly, J. P., Griffiths, J., Brown, S. B., MacRobert, A. J., & Wong, G. (2000). Comparison of the pharmacokinetics and phototoxicity of protoporphyrin IX metabolised from 5-aminlevulinic acid and two derivatives in human skin in vivo.Photochem Photobiol, 72 (4), 569-574. . Publication link: 182081ab-b4a2-42d2-a73a-153003d3da56

1999

  • Azurdia, R. M., Pagliaro, J. A., Diffey, B. L., & Rhodes, L. E. (1999). Sunscreen application by photosensitive patients is inadequate for protection. British Journal of Dermatology, 140(2), 255-258. DOI:10.1046/j.1365-2133.1999.02658.x. Publication link: 39af5f1b-c720-4547-9ec7-e2fa09e983fe
  • Rhodes, L. E., Anstey, A. V., Ryan, A., Charman, C. R., Arlett, C. F., Tyrrell, R. M., ... Marks, R. (1999). Characterisation of photosensitivity in the Smith-Lemli-Opitz Syndrome: a new congenital photosensitivity syndrome.British Journal of Dermatology, 141 (3), 406-414. . Publication link: 72db7840-4a44-4814-9f97-5447d337f20b
  • Rhodes, L., Sarkany, R. P. E., Anstey, A., Diffey, B. L., Jobling, R., Langmack, K., ... Norris, P. G. (1999). Home phototherapy: workshop report of the British Photodermatology Group. Br J Dermatol, 140 (2), 195-199. . Publication link: 98cd08c9-c11a-4278-a763-7e2c5a8f7b60

1998

1997

  • Rhodes, L. E., & Diffey, B. L. (1997). Fluorescence spectroscopy: a rapid, non-invasive method for measurement of skin surface thickness of topical agents. British Journal of Dermatology, 136 (1), 12-17. . Publication link: 1c7ba7d6-5c45-4b89-83f9-066459186da3
  • Rhodes, L. E., Strickland, I., Flanagan, B. F., & Friedmann, P. S. (1997). TNF-alpha and IL-8 are upregulated in the epidermis of normal human skin after UVB exposure: correlation with neutrophil accumulation and E-selectin expression.J Invest Dermatol, 108 (5). . Publication link: f5bda309-ccd0-4bae-a29f-c0b70a46938a
  • Rhodes, L., Ibbotson, S. H., Farr, P. M., Beck, . U., MH, . U., Diffey, B. L., ... White, I. R. (1997). Photopatch testing: methods and indications. Workshop Report, British Photodermatology Group. Br J Dermatol, 136, 371-376. . Publication link: 51ca9dd0-11ef-48fc-b25d-d43bc82f101d
  • Rhodes, L., Rhodes, L. E., Tsoukas, M. M., Anderson, R. R., & Kollias, N. (1997). Iontophoretic delivery of ALA provides a quantitative model for ALA pharmacokinetics and PpIX phototoxicity in human skin. Journal of Investigative Dermatology, 108(1), 87-91. . Publication link: fcc29b08-d8cf-474a-b71e-186bce6b26b6

1995

  • Rhodes, L. E., Durham, B. H., Fraser, W., & Friedmann, P. S. (1995). Dietary fish oil supplementation reduces basal and ultraviolet-induced PGE2 levels in skin and confers photoprotection in light-sensitive subjects. J Invest Dermatol, 105 (4), 532-535. . Publication link: 834d509a-a1ee-46c6-9df1-52f2896be4f3
  • Rhodes, L. E., Tingle, M. D., Park, B. K., Chu, P., Verbov, J. L., & Friedmann, P. S. (1995). Cimetidine improves the therapeutic/toxic ratio of dapsone in patients on chronic dapsone therapy. British Journal of Dermatology, 132(2), 257-262. . Publication link: a76420fb-312a-490d-b084-5599467bbd15

1994

  • Pryce, D. W., Rhodes, L. E., Hardwick, N., & Friedmann, P. S. (1994). Safety and efficacy of longer-term lower-dose cyclosporin A therapy [1]. British Journal of Dermatology, 130(5), 681-682. DOI:10.1111/j.1365-2133.1994.tb13123.x. Publication link: 1d2764fa-0c7e-498a-bab4-ae1b337ff677
  • Rhodes, L. E., Bilsland, D. J., Handfield-Jones, S. E., McKenna, K. E., Wilkinson, S. M., & Zaki, I. (1994). PUVA and methotrexate therapy of psoriasis - how closely do Dermatology departments follow treatment guidelines? On behalf of the Psoriasis Audit Workgroup of the British Association of Dermatologists. Br J Dermatol, 131 (2), 220-225. . Publication link: 32c51654-8994-49bf-871b-4204fe263bf2

1992

  • Rhodes, L. E., & Friedman, P. S. (1992). A comparison of the ultraviolet B-induced erythemal response of back and buttock skin. Photodermatology Photoimmunology and Photomedicine, 9(2), 48-51. . Publication link: 098557e2-a5e5-4228-a283-74a4809aa296

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