Professor Giorgio Terenghi

Photograph of Giorgio Terenghi

Honorary Professor of Tissue Engineering

Blond McIndoe Laboratories
Centre for Tissue Injury & Repair

University of Manchester
Manchester Academic Health Science Centre
3.106 Stopford Building
Oxford Road
Manchester M13 9PT
 

Role

  • Honorary Professor of Tissue Engineering .
  • Director of the UK Centre for Tissue Regeneration (www.ukctr.manchester.ac.uk)
  • Designated Individual for the HTA Research Licence of the University of Manchester
  • Representative for the University of Manchester on the Committee of the N8 Centre for Translational Regenerative Medicine, established through the Northern Way initiative

Memberships of Committees and Professional Bodies

Fellow of the Royal College of Pathologists, London

Research

Surgical treatment of peripheral nerve injury results in poor functional recovery for the patient, leading to significant long-term disability. The main aim of my research is the development of an artificial nerve which would improve the regeneration results, using biopolymer conduits, enzymatically degradable hydrogel matrix and genetically engineered cultured cells. We aim to produce a clinically applicable bioengineered nerve construct through the optimisation of its single components.

Keywords

  • Biomaterial for Nerve Conduits
  • Thermo-Gelling Matrices
  • Pharmacological Neuroprotection
  • Schwann Cells and Stem Cells
  • Neurotrophic Factors
  • Muscle Atrophy and Reinnervation

Qualifications

1968-1973 Faculty of Biological Sciences at the Universita’ degli Studi in Milan
Doctor in Biology, 1973.

 

1973-1974 Ospedale degli Infermi in Biella.
Diploma in Immunohaematology, 1974

 

1978-1980 Department of Anatomy and Human Biology, University of Sheffield.
MSc in Anatomy

 

1981-1985 Royal Postgraduate Medical School, London University.
PhD in Pathology.

 

2001 Honorary Degree in Medicine, University of Umeå, Sweden.

Collaborators and affiliated staff

Professor Mikael Wiberg, Dept. Surgical & Perioperative Science, University of Umeå, Sweden

Professor Martin Birchall, University College London, UK

Dr Valerio Magnaghi, Institute of Endocrinology, Universita' degli Studi, MIlan, Italy

Dr Annamaria Tonazzi, National Research Council (CNR), University of Bari, Italy

Dr Daniel Kalbermatten, Chirurgie Plastique, CHUV, University of Lausanne, Switzerland

Miss Vivien Lees, Plastic & Reconstructive Surgery, Wythenshawe Hospital, Manchester

Prof. Stefano Geuna, Clinical & Biological Sciences, Universita' degli Studi, Torino, Italy

Publications

2012

  • Audisio C, Mantovani C, Raimondo S, Geuna S, Terenghi G, Perroteau I. (2012). Neuregulin 1 administration increases axonal elongation in dissociated primary sensory neuron cultures. Experimental Cell Research, 318, 570-577. eScholarID:175682 | DOI:10.1016/j.yexcr.2012.01.011
  • de Luca AC, Stevens JS, Schroeder SLM, Guibaud J-B, Saiani A, Downes S, Terenghi G. (In-press). Immobilisation of cell-binding peptides on poly-caprolactone film surface to biomimic the peripheral nervous system. Journal of Biomedical Material Research, eScholarID:175702
  • de Luca AC, Terenghi G, Downes S. (2012). Chemical surface modification of poly-caprolactone improves Schwann cells proliferation for peripheral nerve repair. Journal of Tissue Engineering and Regenerative Medicine, epub, eScholarID:175683 | DOI:10.1002/term.1509
  • Englezou P, Degli Esposti M, Wiberg M, Reid AJ, Terenghi G. (2012). Mitochondrial involvement in sensory neuronal cell death and survival. Experimental Brain Research, 221, 357-367. eScholarID:175700 | DOI:10.1007/s00221-012-3179-4
  • Faroni A, Terenghi G, Magnaghi V. (In-press). Expression of gamma-aminobutiric acid type A receptors in Schwann-like adult stem cells. Journal of Molecular Neuroscience, eScholarID:175688
  • Henderson J, Ferguson MWJ, Terenghi G. (2012). The feeling of healing. Plastic and Reconstructive Surgery, 129, 223e-224e. eScholarID:175668 | DOI:10.1097/PRS.0b013e3182365fda
  • Henderson J, Ferguson MWJ, Terenghi G. (2012). The reinnervation pattern of wounds and scars after treatment with transforming growth factor beta isoform. Journal of Plastic Reconstructive and Aesthetic Surgery, 65, 80e-86e. eScholarID:175670 | DOI:10.1016/j.bjps.2011.12.013
  • Mantovani C, Raimondo S, Haneef MS, Geuna S, Terenghi G, Shawcross SG. (2012). Morphological, molecular and functional differences of adult bone marrow- and adipose-derived stem cells isolated from rats of different ages. Experimental Cell Research, 318, 2034-2048. eScholarID:175690 | DOI:10.1016/j.yexcr.2012.05.008
  • Mantovani C, Terenghi G, Shawcross SG. (2012). Isolation of adult stem cells and their differentiation to Schwann cells. Methods in Molecular Biology, 916, 47-57. eScholarID:175707
  • Ouasti S, Kingham PJ, Terenghi G, Tirelli N. (2012). The CD44/integrin interplay and the significance of receptor binding and re-presentation in the uptake of RGD-functionalised hyluronic acid. Biomaterials, 33, 1120-1134. eScholarID:175669 | DOI:10.1016/j.biomaterials.2011.10.009
  • Tomita K, Madura T, Mantovani C, Terenghi G. (2012). Differentiated adipose-derived stem cells promote myelination and enhance functional recovery in a rat model of chronic denervation. Journal of Neuroscience Research, 90, 1392-1402. eScholarID:175674 | DOI:10.1002/jnr.23002
  • West CA, Hart AM, Terenghi G, Wiberg M. (2012). Sensory neurons of the human brachial plexus: a quantitative study employing optical fractionation and in vivo volumetric magnetic resonance imaging. Neurosurgery, 70, 1183-1194. eScholarID:175679 | DOI:10.1227/NEU.0b013e318241ace1

2011

  • Hart A, Terenghi G, Wiberg M. (2011). Tissue engineering for peripheral nerve regeneration. In Pallua N, Suschek CV (Ed.), Tissue Engineering. (pp. 245-262). Berlin Heidelberg: Springer-Verlag. eScholarID:175710
  • Di Summa PG, Kalbermatten DF, Pralong E, Raffoul W, Kingham PJ, Terenghi G. (2011). Long-term in vivo regeneration of peripheral nerves through bioengineered nerve grafts. Neuroscience, 181, 278-291. eScholarID:126107 | DOI:10.1016/j.neuroscience.2011.02.052
  • Faroni A, Mantovani C, Shawcross SG, Motta M, Terenghi G, Magnaghi V. (2011). Schwann-like adult stem cells derived from bone marrow and adipose tissue express gamma-aminobutyric acid type B receptors. Journal of Neuroscience Research, 89, 1351-1362. eScholarID:140208 | DOI:10.1002/jnr.22652
  • Henderson J, Ferguson MWJ, Terenghi G. (2011). The reinnervation and revascularisation of wounds is temporarily altered after treatment with interleukin 10. Wound Repair and Regeneration, 19, 268-273. eScholarID:128302 | DOI:10.1111/j.1524-475X.2011.00667.x
  • Henderson J, Terenghi G, Ferguson MWJ. (2011). The reinnervation and revascularisation pattern of scarless murine fetal wounds. Journal of Anatomy, 218, 660-667. eScholarID:128301 | DOI:10.1111/j.1469-7580.2011.01366.x
  • Madura T, Tomita K, Terenghi G. (2011). Ibuprofen improves functional outcome after axotomy and immediate repair in the peripheral nervous system. Journal of Plastic Reconstructive and Aesthetic Surgery, 64, 1641-1646. eScholarID:140212 | DOI:10.1016/j.bjps.2011.07.014
  • Ouasti S, Donno R, Cellesi F, Sherratt MJ, Terenghi G, Tirelli N. (2011). Network connectivity, mechanical properties and cell adhesion for hyaluronic acid/PEG hydrogels. Biomaterials, 32, 6456-6470. eScholarID:128304 | DOI:10.1016/j.biomaterials.2011.05.044
  • Ouasti S, Kingham PJ, Terenghi G, Tirelli N. (2011). The CD44-integrin interplay and the significance of receptor binding and re-presenttion in the uptake of RGD-functionalised hyaluronic acid. Biomaterials, 33, 1120-1134. eScholarID:140213
  • Reid AJ, Mantovani C, Shawcross SG, Terenghi G, Wiberg M. (2011). Phenotype of distinct primary sensory afferent subpopulations and caspase-3 expression following axotomy. Histochemistry and Cell Biology, 136, 71-78. eScholarID:128305 | DOI:10.1007/s00418-011-0829-8
  • Reid AJ, Sun M, Wiberg M, Downes S, Terenghi G, Kingham PJ. (2011). Nerve repair with adipose-derived stem cells protects dorsal root ganglia neurons from apoptosis. Neuroscience, 199, 515-522. eScholarID:140210 | DOI:10.1016/j.neuroscience.2011.09.064
  • Terenghi G, Hart A, Wiberg M. (2011). The nerve injury and the dying neurons: diagnosis and prevention. The Journal of Hand Surgery, 36E(9), 730-734. eScholarID:140214
  • Terenghi G, Hart A, Wiberg M. (2011). The nerve injury and the dying neurons: diagnosis and prevention. THe Journal of Hand Surgery, 36E, 730-734. eScholarID:175712
  • Tomita K, Terenghi G, Madura T. (2011). Minimally invasive transplantation of Schwann cells into the peripheral nerve - preliminary results in rats. Journal of Plastic Reconstructive and Aesthetic Surgery, 64, 1546-1548. eScholarID:140215 | DOI:10.1016/j.bjps.2011.05.032

2010

  • Kingham PJ, Mantovani C, Terenghi G. (2010). Stem cell and neuron co-cultures for the study of nerve regeneration. In John W Haycock (Ed.), Methods in Molecular Biology. Humana Press. eScholarID:103201
  • Cristina Mantovani, Daljeet Mahay, Paul J Kingham, Giorgio Terenghi, Susan G Shawcross, Mikael Wiberg. (2010). Bone Marrow- and Adipose-derived Stem Cells Show Expression of Myelin mRNAs and Proteins. Regenerative Medicine, 5(4), 403-410. eScholarID:1d18901 | DOI:10.2217/rme.10.15
  • di Summa PG, Kingham PJ, Raffoul W, Wiberg M, Terenghi G. (2010). Adipose-derived stem cells enhance peripheral nerve regeneration. Journal of Plastic Reconstructive and Aesthetic Surgery, 63, 1544-1552. eScholarID:103180 | DOI:10.1016/j.bjps.2009.09.012
  • Erba P, Mantovani C, Kalbermatten DF, Pierer G, Terenghi G, Kingham PJ. (2010). Regeneration potential and survival of transplanted undifferentiated adipose tissue-derived stem cells in peripheral nerve conduits. Journal of Plastic Reconstructive and Aesthetic Surgery, 63, e811-e817. eScholarID:103208 | DOI:10.1016/j.bjps.2010.08.013
  • Erba P, Terenghi G, Kingham PJ. (2010). Neural differentiation and therapeutic potential of adipose-derived stem cells. Current Stem Cell Research and Therapy, 5, 1-7. eScholarID:103200
  • Herzmann C, Smith C, Johnson M, Byrne P, Terenghi G, Duraisamy Y, Youle M. (2010). A prospective double blind randomised placebo controlled trial evaluating acetyl-L-carnitine (ALCAR) for the prevention of distal symmetric polyneuropathy in HIV infected individuals. Journal of Aids and Clinical Research, 1(3), 1-4. eScholarID:128300
  • Kingham PJ, Mantovani C, Terenghi G. (2010). Notch independent signalling mediates Schwann cell-like differentiation of adipose-derived stem cells. Neuroscience Letters, 467, 164-168. eScholarID:103182
  • Reid AJ, Welin D, Wiberg M, Terenghi G, Novikov LN. (2010). Peripherin and ATF3 genes are differentially regulated in regenerating and non-regenerating primary sensory neurons. Brain Research, 1310, 1-7. eScholarID:103181 | DOI:10.1016/j.brainres.2009.11.011
  • Sun M, Kingham PJ, Reid AJ, Armstrong SJ, Terenghi G, Downes S. (2010). In vitro and in vivo testing of novel ultrathin PCL and PCL-PLA blend film as peripheral nerve conduits. Journal of Biomedical Material Research, Part A, 93, 1470-1481. eScholarID:103171
  • Sun M, McGowan M, Kingham PJ, Terenghi G, Downes S. (2010). Novel thin-walled nerve conduit with microgrooved surface patterns for enhanced peripheral nerve repair. Journal of Material Science - Material Medical, 21, 2765-2774. eScholarID:128299 | DOI:10.1007/s10856-010-4120-7
  • Tse K-H, Sun M, Mantovani C, Terenghi G, Downes S, Kingham P. (2010). In vitro evaluation of polyester-based scaffolds seeded with adipose derived stem cells for peripheral nerve regeneration. Journal of Biomedical Material Research, Part A, 95A, 701-708. eScholarID:128297
  • Wilson DH, Hart A, Terenghi G, Wiberg M. (2010). Acetyl-L-carnitine increases nerve regeneration and target organ reinnervation: a morphological study. Journal of Plastic Reconstructive and Aesthetic Surgery, 63, 1186-1195. eScholarID:103179 | DOI:10.1016/j.bjps.2009.05.039

2009

  • Kingham PJ, Terenghi G. (2009). Autonomic neuroplasticty and regeneration. In George Adelman, Barry H. Smith (Ed.), Encyclopedia of Neuroscience. (pp. 1071-1021). Elsevier B.V.. eScholarID:103197
  • Aberg M, Ljungberg C, Edin E, Millqvist H, Nordh E, Theorin A, Terenghi G, Wiberg M. (2009). Clinical evaluation of a resorbable wrap-around implant as an alternative to nerve repair: A prospective, assessor-blinded, randomised clinical study of sensory, motor and functional recovery after peripheral nerve repair. Journal of Plastic Reconstructive Aesthetic Surgery, 62, 1503-1509. eScholarID:1d18938 | DOI:10.1016/j.bjps.2008.06.041
  • Adam J. Reid, Susan G. Shawcross, Alex E. Hamilton, Mikael Wiberg, Giorgio Terenghi. (2009). N-Acetylcysteine alters apoptotic gene expression in axotomised primary sensory afferent subpopulations. Neuroscience Research, 65, 148-155. eScholarID:1d21208 | DOI:10.1016/j.neures.2009.06.008
  • Brohlin M, Mahay D, Shawcross SG, Novikov LN, Terenghi G, Wiberg M, Novikova LN. (2009). Characterisation of human mesenchymal stem cells following differentiation into Schwann cell-like cells. Neuroscience Research, 64, 41-49. eScholarID:103184 | DOI:10.1016/j.neures.2009.01.010
  • Terenghi G, Wiberg M, Kingham PJ. (2009). Use of stem cells for improving nerve regeneration. International Review of Neurobiology, 87, 393-403. eScholarID:103199 | DOI:10.1016/S0074-7742(09)87021-9
  • Terenghi G, Wiberg M, Kingham PJ. (2009). Use of stem cells for improving nerve regeneration. International Review of Neurobiology, 87, 393-403. eScholarID:175718 | DOI:10.1016/S0074-7742(09)87021-9

2008

  • Armstrong S, Wiberg M, Terenghi G, Kingham P. (2008). Laminin activates NF-kappaB in Schwann cells to enhance neurite outgrowth. Neurosci Lett, 439( 1), 42-6. eScholarID:1d18935 | DOI:10.1016/j.neulet.2008.04.091
  • Hart A, Terenghi G, Wiberg M. (2008). Neuronal death after peripheral nerve injury and experimental strategies for neuroprotection. Neurol Res, 30( 10), 999-1011. eScholarID:1d18936 | DOI:10.1179/174313208X362479
  • Kalbermatten D, Erba P, Mahay D, Wiberg M, Pierer G, Terenghi G. (2008). Schwann cell strip for peripheral nerve repair. J Hand Surg Eur Vol, 33( 5), 587-94. eScholarID:1d18932 | DOI:10.1177/1753193408090755
  • Kalbermatten D, Pettersson J, Kingham P, Pierer G, Wiberg M, Terenghi G. (2008). New fibrin conduit for peripheral nerve repair. Journal of Reconstructive Microsurgery, 25( 1), 27-33. eScholarID:1d18937 | DOI:10.1055/s-0028-1090619
  • Kalbermatten DF, Kingham PJ, Mahay D, Mantovani C, Pettersson J, Raffoul W, Balcin H, Pierer G, Terenghi G. (2008). Fibrin matrix for suspension of regenerative cells in an artificial nerve conduit. Journal of Plastic, Reconstructive and Aesthetic Surgery, 61, 669-675. eScholarID:1d18908 | DOI:10.1016/j.bjps.2007.12.015
  • Kleyn, C, Schneider, L, Saraceno, R, Mantovani, C, Richards, H, Fortune, D, Cumberbatch, M, Dearman, R, Terenghi, G, Kimber, I, Griffiths, C. (2008). The Effects of Acute Social Stress on Epidermal Langerhans' Cell Frequency and Expression of Cutaneous Neuropeptides. J Invest Dermatol, 151, 50-64. eScholarID:1d16842 | DOI:10.1038/sj.jid.5701144
  • Mahay D, Terenghi G, Shawcross SG. (2008). Cellular and molecular characterisation of growth factors in differentiated mesenchymal stem cells. Biotechnology and Applied Biochemistry, 51, 167-176. eScholarID:1d17536 | DOI:10.1042/BA20070212
  • Mahay D, Terenghi G, Shawcross SG. (2008). Schwann cell mediated trophic effects by differentiated mesenchymal stem cells. Exp Cell Res, 314, 2692-2701. eScholarID:1d17535 | DOI:10.1016/j.yexcr.2008.05.013
  • Thornton MR, Shawcross SG, Mantovani C, Kingham PJ, Kingham PJ, Birchall MA, Terenghi G, Terenghi G. (2008). Neurotrophin 3 and neurotrophin 4 differentially regulate NCAM, L1 and N-cadherin expression during peripheral nerve regeneration. Biotechnol Appl Biochem, 49, 165-174. eScholarID:1d16019 | DOI:10.1042/BA20070040

2007

  • Kingham PJ, Terenghi G. (2007). Nerve bioengineering. In Boccaccini AR, Gough JE (Ed.), Tissue engineering using ceramics and polymers. (pp. 466-496). Cambridge: Woodhead Publishing. eScholarID:103195
  • Armstrong S J, Wiberg M, Terenghi G. (2007). ECM Molecules mediate both Schwann cell proliferation and activation to enhance neurite outgrowth. Tissue Engineering, 13(12), 2863-2870. eScholarID:1d16624 | DOI:10.1089/ten.2007.0055
  • Kelly EJ, Jacoby C, Terenghi G, Mennen U, Ljungberg C, Wiberg M. (2007). End-to-side nerve coaptation: a qualitative and quantitative assessment in the primate. J Plast Reconstr Aesthet Surg, 60( 1), 1-12. eScholarID:1d30495
  • Kingham PJ, Kalbermatten DF, Mahay D, Armstrong SJ, Wiberg M, Terenghi G. (2007). Adipose-derived stem cells differentiate into a Schwann cell Phenotype and promote neurite outgrowth in vitro. Experimental Neurology, 207(2), 267-274. eScholarID:1d16623
  • Kingham PJ, Kingham PJ, Hughes A, Mitchard L, Burt R, Murison P, Jones A, Terenghi G, Birchall MA. (2007). Effect of neurotrophin-3 on reinnervation of the larynx using the phrenic nerve transfer technique. Eur J Neurosci, 25( 2), 331-340. eScholarID:1d15343 | DOI:10.1111/j.1460-9568.2007.05310.x
  • West C, Davies KE, Andrew Hart, Mikael Wiberg, Williams SR, Terenghi G. (2007). Volumetric magnetic resonance imaging of dorsal root ganglia for the objective quantitative assessment of neuron death after peripheral nerve injury. Experimental Neurology, 203, 22-33. eScholarID:1d27539 | DOI:10.1016/j.expneurol.2006.07.013
  • West CA, Hart AM, Terenghi G, Wiberg M. (2007). Analysis of the dose-response of N-acetylcysteine in the prevention of sensory neuronal loss after peripheral nerve injury. Acta Neurochirurgica Supplement, 100, 29-31. eScholarID:1d16626 | DOI:10.1007/978-3-211-72958-8_6
  • Wilson A, Hart A, Brännström T, Wiberg M, Terenghi G. (2007). Delayed acetyl-L-carnitine administration and its effect on sensory neuronal rescue after peripheral nerve injury. J Plast Reconstr Aesthet Surg, 60(2), 114-118. eScholarID:1d31274 | DOI:10.1016/j.bjps.2006.04.017

2006

  • Caddick J, Kingham PJ, Gardiner N, Wiberg M, Terenghi G. (2006). Phenotypic and functional characteristics of mesenchymal stem cells differentiated along a Schwann cell lineage. Glia, 54( 8), 840-9. eScholarID:1d14083 | DOI:10.1002/glia.20421
  • Henderson J, Terenghi G, McGrouther D, Ferguson M. (2006). The reinnervation pattern of wounds and scars may explain their sensory symptoms. J Plast Reconstr Aesthet Surg, 59( 9), 942-50. eScholarID:1d13763
  • Kingham PJ, Terenghi G, Birchall M. (2006). Tissue engineering strategies for reinnervation of the larynx. Clin Otolaryngol, 31( 3), eScholarID:1d30389
  • Kingham PJ, Terenghi G. (2006). Bioengineered nerve regeneration and muscle reinnervation. J Anat, 209( 4), 511-526. eScholarID:1d30450
  • Novikova L, Mosahebi A, Wiberg M, Terenghi G, Kellerth J, Novikov L. (2006). Alginate hydrogel and matrigel as potential cell carriers for neurotransplantation. J Biomed Mater Res A, 77( 2), 242-52. eScholarID:1d31511
  • R Saraceno, Kleyn CE, Terenghi G, Griffiths CEM. (2006). The role of neuropeptides in psoriasis. British Journal of Dermatology, 154, 876-882. eScholarID:1d13480 | DOI:10.1111/j.1365-2133.2006.07518.x
  • Saraceno R, Kleyn C, Terenghi G, Griffiths C. (2006). The role of neuropeptides in psoriasis. Br J Dermatol, 155( 5), 876-82. eScholarID:1d30469
  • Zhang C, Terenghi G, Mantovani C, Wiberg M. (2006). Neuronal survival, regeneration and musclemorphology after posterior C7 nerve transfer: an experimental study. J Plast Reconstr Aesthet Surg, 59( 7), 717-25. eScholarID:1d30303

2005

  • Kelly E, Terenghi G, Hazari A, Wiberg M. (2005). Nerve fibre and sensory end organ density in the epidermis and papillary dermis of the human hand. Br J Plast Surg, 58( 6), 774-9. eScholarID:1d30311
  • Kingham PJ, Birchall MA, Burt R, Jones A, Terenghi G. (2005). Reinnervation of laryngeal muscles: A study of changes in myosin heavy chain expression. Muscle Nerve, 32 (6), 761-766. eScholarID:1d12063
  • Mohanna P, Terenghi G, Wiberg M. (2005). Composite PHB-GGF conduit for long nerve gap repair: a long-term evaluation. Scand J Plast Reconstr Surg Hand Surg, 39( 3), 129-37. eScholarID:1d30175
  • Thornton M, Mantovani C, Birchall M, Terenghi G. (2005). Quantification of N-CAM and N-cadherin expression in axotomized and crushed rat sciatic nerve. J Anat, 206( 1), 69-78. eScholarID:1d12931

2004

  • Birchall M, Idowu B, Murison P, Jones A, Burt R, Ayling S, Stokes C, Pope L, Terenghi G. (2004). Laryngeal abductor muscle reinnervation in a pig model. Acta Otolaryngol, 124( 7), 839-46. eScholarID:1d28803
  • McKay Hart A, Terenghi G, Kellerth J, Wiberg M. (2004). Sensory neuroprotection, mitochondrial preservation, and therapeutic potential of N-acetyl-cysteine after nerve injury. Neuroscience, 125( 1), 91-101. eScholarID:1d9565
  • McKay Hart A, Terenghi G. (2004). Frozen-section fluorescence microscopy and stereology in the quantification of neuronal death within dorsal root ganglia. J Mol Histol, 35( 6), 565-80. eScholarID:1d29176
  • McKay Hart A, Wilson A, Montovani C, Smith C, Johnson M, Terenghi G, Youle M. (2004). Acetyl-l-carnitine: a pathogenesis based treatment for HIV-associated antiretroviral toxic neuropathy. AIDS, 18( 11), 1549-60. eScholarID:1d9564 | DOI:10.1097/01.aids.0000131354.14408.fb
  • Tohill MP, Mann D, Mantovani C, Wiberg M, Terenghi G. (2004). Green fluorescent protein is a stable morphological marker for schwann cell transplants in bioengineered nerve conduits. Tissue Eng, 10( 9-10), 1359-67. eScholarID:1d9563
  • Tohill MP, Terenghi G. (2004). Stem cell plasticity and therapy for injuries of the peripheral nervous system. Biotechnol Appl Biochem, eScholarID:1d7813
  • Tohill MP, Terenghi G. (2004). Stem-cell plasticity and therapy for injuries of the peripheral nervous system. Biotechnol Appl Biochem, 40( Pt 1), 17-24. eScholarID:1d29439
  • Tohill MP, Tohill MP, Terenghi G. (2004). Stem cell plasticity and therapy for injuries of the peripheral nervous system. Biotechnol Appl Biochem, eScholarID:1d30656
  • Tympanidis P, Casula M, Yiangou Y, Terenghi G, Dowd P, Anand P. (2004). Increased vanilloid receptor VR1 innervation in vulvodynia. Eur J Pain, 8( 2), 129-33. eScholarID:1d29595
  • Tympanidis P, Casula M. A, Yiangou Y, Terenghi G, Dowd P, Anand P. (2004). Increased vanilloid receptor VR1 innervation in vulvodynia. Eur J Pain, 8, 2, 129-33. eScholarID:1d7814
  • Zhang C, Ma J, Terenghi G, Mantovani C, Wiberg M. (2004). Phrenic nerve transfer in the treatment of brachial plexus avulsion: an experimental study of nerve regeneration and muscle morphology in rats. Microsurgery, 24( 3), 232-40. eScholarID:1d29440
  • Tohill MP, Mantovani C, Wiberg M, Terenghi G. (2004). Rat bone marrow mesenchymal stem cells express glial markers and stimulate nerve regeneration. Neurosci Lett, 362( 3), 200-3. eScholarID:17d419

2003

  • Greig A, James S, McGrouther D, Terenghi G, Burnstock G. (2003). Purinergic receptor expression in the regeneration epidermis in a rat model of normal and delayed wound healing. Exp Dermatol, 12( 6), 860-71. eScholarID:1d29343
  • Greig A, Linge C, Terenghi G, McGrouther D, Burnstock G. (2003). Purinergic receptors are part of a functional signaling system for proliferation and differentiation of human epidermal keratinocytes. J Invest Dermatol, 120( 6), 1007-15. eScholarID:1d29441
  • Greig A. V, James S. E, McGrouther D, Terenghi G, Burnstock G. (2003). Purinergic receptor expression in the regeneration epidermis in a rat model of normal and delayed wound healing. Exp Dermatol, 12, 6, 860-71. eScholarID:1d7613
  • Greig A. V, Linge C, Terenghi G, McGrouther D, Burnstock G. (2003). Purinergic receptors are part of a functional signaling system for proliferation and differentiation of human epidermal keratinocytes. J Invest Dermatol, 120, 6, 1007-15. eScholarID:1d7369
  • McKay Hart A, Wiberg M, Terenghi G. (2003). Exogenous leukaemia inhibitory factor enhances nerve regeneration after late secondary repair using a bioartificial nerve conduit. Br J Plast Surg, 56( 5), 444-50. eScholarID:1d29596
  • McKay Hart A, Wiberg M, Terenghi G. (2003). Exogenous leukaemia inhibitory factor enhances nerve regeneration after late secondary repair using a bioartificial nerve conduit. Br J Plast Surg, 56, 5, 444-50. eScholarID:1d7379
  • Mohanna P, Young R, Wiberg M, Terenghi G. (2003). A composite poly-hydroxybutyrate-glial growth factor conduit for long nerve gap repairs. J Anat, 203( 6), 553-65. eScholarID:1d28752
  • Mohanna P. N, Young R. C, Wiberg M, Terenghi G. (2003). A composite poly-hydroxybutyrate-glial growth factor conduit for long nerve gap repairs. J Anat, 203, 6, 553-65. eScholarID:1d7805
  • Mosahebi A, Wiberg M, Terenghi G. (2003). Addition of fibronectin to alginate matrix improves peripheral nerve regeneration in tissue-engineered conduits. Tissue Eng, 9( 2), 209-18. eScholarID:1d29442
  • Mosahebi A, Wiberg M, Terenghi G. (2003). Addition of fibronectin to alginate matrix improves peripheral nerve regeneration in tissue-engineered conduits. Tissue Eng, 9, 2, 209-18. eScholarID:1d7380
  • Simon M, Porter R, Brown R, Coulton G, Terenghi G. (2003). Effect of NT-4 and BDNF delivery to damaged sciatic nerves on phenotypic recovery of fast and slow muscles fibres. Eur J Neurosci, 18( 9), 2460-6. eScholarID:1d28753
  • Simon M, Porter R, Brown R, Coulton G. R, Terenghi G. (2003). Effect of NT-4 and BDNF delivery to damaged sciatic nerves on phenotypic recovery of fast and slow muscles fibres. Eur J Neurosci, 18, 9, 2460-2466. eScholarID:1d7381
  • Tympanidis P, Terenghi G, Dowd P. (2003). Increased innervation of the vulval vestibule in patients with vulvodynia. Br J Dermatol, 148( 5), 1021-7. eScholarID:1d28804
  • Tympanidis P, Terenghi G, Dowd P. (2003). Increased innervation of the vulval vestibule in patients with vulvodynia. Br J Dermatol, 148, 5, 1021-7. eScholarID:1d7424
  • Walbeehm E, Dudok van Heel E, Kuypers P, Terenghi G, Hovius S. (2003). Nerve compound action current (NCAC) measurements and morphometric analysis in the proximal segment after nerve transection and repair in a rabbit model. J Peripher Nerv Syst, 8( 2), 108-15. eScholarID:1d29488
  • Walbeehm E. T, Dudok van Heel E. B, Kuypers P. D, Terenghi G, Hovius S. E. (2003). Nerve compound action current (NCAC) measurements and morphometric analysis in the proximal segment after nerve transection and repair in a rabbit model. J Peripher Nerv Syst, 8, 2, 108-15. eScholarID:1d7382
  • Wiberg M, Hazari A, Ljungberg C, Pettersson K, Backman C, Nordh E, Kwast-Rabben O, Terenghi G. (2003). Sensory recovery after hand reimplantation: a clinical, morphological, and neurophysiological study in humans. Scand J Plast Reconstr Surg Hand Surg, 37( 3), 163-73. eScholarID:1d30659
  • Wiberg M, Hazari A, Ljungberg C, Pettersson K, Backman C, Nordh E, Kwast-Rabben O, Terenghi G. (2003). Sensory recovery after hand reimplantation: a clinical, morphological, and neurophysiological study in humans. Scand J Plast Reconstr Surg Hand Surg, 37, 3, 163-73. eScholarID:1d7383
  • Wiberg M, Terenghi G. (2003). Will it be possible to produce peripheral nerves? Surg Technol Int, 11, 303-10. eScholarID:1d30658
  • Wiberg M, Terenghi G. (2003). Will it be possible to produce peripheral nerves? Surg Technol Int, 11, 303-10. eScholarID:1d7815
  • Wilson A, Hart A, Brannstrom T, Wiberg M, Terenghi G. (2003). Primary sensory neuronal rescue with systemic acetyl-L-carnitine following peripheral axotomy. A dose-response analysis. Br J Plast Surg, 56( 8), 732-9. eScholarID:1d29344
  • Wilson A. D, Hart A, Brannstrom T, Wiberg M, Terenghi G. (2003). Primary sensory neuronal rescue with systemic acetyl-L-carnitine following peripheral axotomy. A dose-response analysis. Br J Plast Surg, 56, 8, 732-9. eScholarID:1d7384

2002

  • Hart A. M, Wiberg M, Youle M, Terenghi G. (2002). Systemic acetyl-L-carnitine eliminates sensory neuronal loss after peripheral axotomy: a new clinical approach in the management of peripheral nerve trauma. Exp Brain Res, 145, 2, 182-9. eScholarID:1d7801
  • McKay Hart A, Brannstrom T, Wiberg M, Terenghi G. (2002). Primary sensory neurons and satellite cells after peripheral axotomy in the adult rat: timecourse of cell death and elimination. Exp Brain Res, 142, 3, 308-18. eScholarID:1d7804
  • McKay Hart A, Wiberg M, Terenghi G. (2002). Pharmacological enhancement of peripheral nerve regeneration in the rat by systemic acetyl-L-carnitine treatment. Neurosci Lett, 334( 3), 181-5. eScholarID:1d28812
  • McKay Hart A, Wiberg M, Terenghi G. (2002). Pharmacological enhancement of peripheral nerve regeneration in the rat by systemic acetyl-L-carnitine treatment. Neurosci Lett, 334, 3, 181-5. eScholarID:1d7803
  • McKay Hart A, Wiberg M, Youle M, Terenghi G. (2002). Systemic acetyl-L-carnitine eliminates sensory neuronal loss after peripheral axotomy: a new clinical approach in the management of peripheral nerve trauma. Exp Brain Res, 145( 2), 182-9. eScholarID:1d29443
  • Mosahebi A, Fuller P, Wiberg M, Terenghi G. (2002). Effect of allogeneic Schwann cell transplantation on peripheral nerve regeneration. Exp Neurol, 173( 2), 213-23. eScholarID:1d29597
  • Mosahebi A, Fuller P, Wiberg M, Terenghi G. (2002). Effect of allogeneic Schwann cell transplantation on peripheral nerve regeneration. Exp Neurol, 173, 2, 213-23. eScholarID:1d7808
  • Novikov L, Novikova L, Mosahebi A, Wiberg M, Terenghi G, Kellerth J. (2002). A novel biodegradable implant for neuronal rescue and regeneration after spinal cord injury. Biomaterials, 23( 16), 3369-76. eScholarID:1d29182
  • Novikov L. N, Novikova L. N, Mosahebi A, Wiberg M, Terenghi G, Kellerth J. O. (2002). A novel biodegradable implant for neuronal rescue and regeneration after spinal cord injury. Biomaterials, 23, 16, 3369-76. eScholarID:1d7809
  • Simon M, Mann D, Coulton G, Terenghi G. (2002). Differential tyrosine kinase C mRNA distribution in extensor digitorum longus and soleus motoneurons in adult rats: effect of axotomy and neurotrophin-3 treatment. Neurosci Lett, 320( 1-2), 9-12. eScholarID:1d29183
  • Simon M, Mann D, Coulton G, Terenghi G. (2002). Differential tyrosine kinase C mRNA distribution in extensor digitorum longus and soleus motoneurons in adult rats: effect of axotomy and neurotrophin-3 treatment. Neurosci Lett, 320, 1-2, 9-12. eScholarID:1d7811
  • Young R, Wiberg M, Terenghi G. (2002). Poly-3-hydroxybutyrate (PHB): a resorbable conduit for long-gap repair in peripheral nerves. Br J Plast Surg, 55( 3), 235-40. eScholarID:1d29489
  • Young R. C, Wiberg M, Terenghi G. (2002). Poly-3-hydroxybutyrate (PHB): a resorbable conduit for long-gap repair in peripheral nerves. Br J Plast Surg, 55, 3, 235-40. eScholarID:1d7816

2001

  • Coward K, Mosahebi A, Plumpton C, Facer P, Birch R, Tate S, Bountra C, Terenghi G, Anand P. (2001). Immunolocalisation of sodium channel NaG in the intact and injured human peripheral nervous system. J Anat, 198( Pt 2), 175-80. eScholarID:1d29490
  • Coward K, Mosahebi A, Plumpton C, Facer P, Birch R, Tate S, Bountra C, Terenghi G, Anand P. (2001). Immunolocalisation of sodium channel NaG in the intact and injured human peripheral nervous system. J Anat, 198, Pt 2, 175-80. eScholarID:1d7800
  • Mosahebi A, Simon M, Wiberg M, Terenghi G. (2001). A novel use of alginate hydrogel as Schwann cell matrix. Tissue Eng, 7( 5), 525-34. eScholarID:1d29345
  • Mosahebi A, Woodward B, Wiberg M, Martin R, Terenghi G. (2001). Retroviral labeling of Schwann cells: in vitro characterization and in vivo transplantation to improve peripheral nerve regeneration. Glia, 34( 1), 8-17. eScholarID:1d28760
  • Mosahebi A, Woodward B, Wiberg M, Martin R, Terenghi G. (2001). Retroviral labeling of Schwann cells: in vitro characterization and in vivo transplantation to improve peripheral nerve regeneration. Glia, 34, 1, 8-17. eScholarID:1d7807
  • Shembalkar P, Till S, Boettger M, Terenghi G, Tate S, Bountra C, Anand P. (2001). Increased sodium channel SNS/PN3 immunoreactivity in a causalgic finger. Eur J Pain, 5( 3), 319-23. eScholarID:1d28759
  • Shembalkar P. K, Till S, Boettger M. K, Terenghi G, Tate S, Bountra C, Anand P. (2001). Increased sodium channel SNS/PN3 immunoreactivity in a causalgic finger. Eur J Pain, 5, 3, 319-23. eScholarID:1d7810

2000

  • Hobson M. I, Green C. J, Terenghi G. (2000). VEGF enhances intraneural angiogenesis and improves nerve regeneration after axotomy. J Anat, 197 Pt 4, 591-605. eScholarID:1d7802