Professor Ralf Paus

Photograph of Ralf Paus

Professor of Cutaneous Medicine, University of Manchester and Professor of Dermatology and Experimental Dermatology, University of Luebeck


  Professor of Cutaneous Medicine
  Dermatological Sciences Research Group
  School of Translational Medicine
  University of Manchester
  Stopford Building
  Oxford Road
  Manchester M13 9PL
 

Role

Professor Ralf Paus researches into hair disorders, skin neuroendocrinology,  and the science and applications of stem cells residing in the skin.

Research

Ralf researches into the biology and pathology of the hair follicle as a microcosmic miniorgan in which many of the fundamental problems of biology can be studied exemplarily. Currently, he is most intrigued by the astounding neuroendocrine properties of the human hair follicle, their impact on mitochondrial function and hair follicle immune status, and the use ofadult stem cells populations associated with human skin appendages for regenerative medicine pursposes. 

Ralf's particular interest is in:

  • better defining and in manipulating various neuroendocrine pathways established in the human hair follicle (HPA and HPT axis equivalent systems) and in elucidating novel functions of this neuroendocrine activity
  • neuroendocrine controls of mitochondrial activity and biogenesis in human skin
  • understanding the controls and functions of hair follicle immune privilege and its disorders that lead to alopecia areata or scarring alopecia
  • characterizing, selectively labelling, isolating and differentiating various stem cells populations associated with human scalp skin and its appendages
  • role of clock genes in human growth control

Methodologically, Ralf employs mainly human hair follicle and scalp skin organ culture, K15-GFP+ human epithelial hair follicle stem cells, and immunohistology/immunofluorescence, and analyzes the hair and skin phenotype of relevant mouse mutants.

Biography

After his medical studies at the Unversities of Wuerzburg, Berlin and Vienna, MD thesis work at the University of South Florida, Tampa, USA, and an internship at the University Hospitals of Basle and Zurich, Switzerland, Ralf graduated from the Free University of Berlin (1987).

Following post-doctoral research at Yale University (1987-90), Ralf trained as a clinical dermatologist in Berlin, where he became consultant dermatologist and junior faculty at the Charité University Hospital. From 1999-2004 Ralf served as Professor and Vice-Chair of the Dept. of Dermatology, University Hospital Hamburg-Eppendorf, University of Hamburg. He was Visiting Scholar at the University of California, San Diego (1992), Visiting Professor at the Dept. of Molecular Medicine at the Max-Planck-Institute for Biochemistry, Munich-Martinsried (2005), and Honorary Visiting Professor at the University of Bradford until 2010 and again since 2012.


After taking up  his current position as Head of Experimental Dermatology, Dept. of Dermatology, University of Luebeck, Germany (2005), Ralf  joined the University of Manchester in 2008 as Professor of Cutaneous Medicine).

Ralf has been Editor of Experimental Dermatology since 2007.
 

Collaborators and affiliated staff

Professor Enrique Amaya - The Healing Foundation, University of Manchester

Publications

2016

  • Purba, T., Brunken, L., Hawkshaw, N., Hardman, J., & Paus, R. (2016). A Primer for Studying Cell Cycle Dynamics of the Human Hair Follicle. Experimental Dermatology (Online).
    . Publication link: d721a197-734f-4382-9971-837f4856375f

2014

  • Al-Nuaimi, Y., Hardman, J. A., Bíró, T., Haslam, I. S., Philpott, M. P., Tóth, B. I., ... Paus, R. (2014). A meeting of two chronobiological systems: Circadian proteins period1 and bmal1 modulate the human hair cycle clock. Journal of Investigative Dermatology, 134(3), 610-619. DOI:10.1038/jid.2013.366
    . Publication link: 5880be05-8426-4cdf-8db4-c0b9d761b7ce
  • Bertolini, M., Zilio, F., Rossi, A., Kleditzsch, P., Emelianov, V. E., Gilhar, A., ... Paus, R. (2014). Abnormal interactions between perifollicular mast cells and CD8+ T-cells may contribute to the pathogenesis of alopecia areata. PLoS ONE, 9(5), [e94260]. DOI:10.1371/journal.pone.0094260
    . Publication link: 516fa36b-c472-4915-9f46-ffb8fcce8edd
  • Bundy, C., Chiang, Y. Z., Griffiths, C. E. M., Paus, R., Harries, M. J., Z, C. Y., ... J, H. M. (2014). The role of beliefs: Lessons from a pilot study on illness perception, psychological distress, and quality of life in patients with primary cicatricial alopecia. British Journal of Dermatology, 172(1). DOI:10.1111/bjd.13259
    . Publication link: b4f105b8-985a-40ed-96e3-c83823bb4f01 | PubMed:25039441
  • Busse, D., Kudella, P., Grüning, N. M., Gisselmann, G., Ständer, S., Luger, T., ... Benecke, H. (2014). A Synthetic Sandalwood Odorant Induces Wound-Healing Processes in Human Keratinocytes via the Olfactory Receptor OR2AT4. Journal of Investigative Dermatology. DOI:10.1038/jid.2014.273
    . Publication link: aaaf8e3f-9b61-4ca8-b096-4ef5aab3fd1d
  • Dahlhoff, M., Frances, D., Kloepper, J. E., Paus, R., Schäfer, M., Niemann, C., & Schneider, M. R. (2014). Overexpression of epigen during embryonic development induces reversible, epidermal growth factor receptor-dependent sebaceous gland hyperplasia. Molecular and Cellular Biology, 34(16), 3086-3095. DOI:10.1128/MCB.00302-14
    . Publication link: f2464300-f6b9-4b51-b0af-e1345cc22806
  • Haslam, I. S., Hardman, J. A., Tobin, D. J., Farjo, N., Farjo, B., Al-Nuaimi, Y., ... Paus, R. (2014). The Peripheral Clock Regulates Human Pigmentation.The Journal of Investigative Dermatology. DOI:10.1038/jid.2014.442
    . Publication link: 1934bdfd-71a9-4eb7-9310-264f3b82db4d
  • Haslam, I. S., Roubos, E. W., Mangoni, M. L., Yoshizato, K., Vaudry, H., Kloepper, J. E., ... Paus, R. (2014). From frog integument to human skin: Dermatological perspectives from frog skin biology. Biological Reviews, 89(3), 618-655. DOI:10.1111/brv.12072
    . Publication link: 615cb9e7-4a54-4ff7-ac8f-6865e7121a24
  • Haslam, I., Kloepper, J. E., Ernst, N., Krieger, K., Bodó, E., Bíró, T., ... Paus, R. (2014). NF-κB activity is required for anagen maintenance in human hair follicles in vitro. Journal of Investigative Dermatology, 134(7), 2036-2038. DOI:10.1038/jid.2014.82
    . Publication link: db6bd69a-9b90-401d-9d39-ec7277c270a1
  • Oláh, A., Tóth, B. I., Borbíró, I., Sugawara, K., Szöllõsi, A. G., Czifra, G., ... Bíró, T. (2014). Cannabidiol exerts sebostatic and antiinflammatory effects on human sebocytes. Journal of Clinical Investigation, 124(9), 3713-3724. DOI:10.1172/JCI64628
    . Publication link: 65670047-badd-46c4-9d27-f1b5416f8a29
  • Paus, R., & Schneider, M. R. (2014). Deciphering the functions of the hair follicle infundibulum in skin physiology and disease.Unknown Journal.
    . Publication link: 1f90fd12-f7fa-416a-b67e-a27c41b64c1a
  • Paus, R., Böhm, M., Bodó, E., & Funk, W. (2014). α-Melanocyte-stimulating hormone: a protective peptide against chemotherapy-induced hair follicle damage?. British Journal of Dermatology, 170(4), 956-960. DOI:10.1111/bjd.12759
    . Publication link: d05de5f2-cd4e-426e-8867-f21de2bc9d48
  • Paus, R., Chen, J., Laclef, C., Moncayo, A., Snedecor, E. R., Yang, N., ... Clark, R. A. (2014). The Ciliopathy Gene Rpgrip1l Is Essential For Hair Follicle Development. The Journal of Investigative Dermatology. DOI:10.1038/jid.2014.483
    . Publication link: 0e9df54d-a456-45b6-b1f8-dfd5a061d7c2
  • Paus, R., Fischer, T. W., Herczeg-Lisztes, E., Funk, W., Zillikens, D., & Bíró, T. (2014). Differential effects of caffeine on hair shaft elongation, matrix and outer root sheath keratinocyte proliferation, and TGF-β2-/IGF-1-mediated regulation of hair cycle in male and female human hair follicles in vitro.British Journal of Dermatology. DOI:doi: 10.1111/bjd.13114
    . Publication link: cb8f637f-e19c-4796-b108-6f8f993dceb0
  • Paus, R., Geyfman, M., Plikus, M. V., Treffeisen, E., & Andersen, B. (2014). Resting no more: re-defining telogen, the maintenance stage of the hair growth cycle. Biology Bulletin Reviews. DOI:10.1111/brv.12151
    . Publication link: 184aceb0-876b-490f-ab8c-66adedbbc54d
  • Paus, R., Kloepper, J. E., Baris, O. R., Reuter, K., Kobayashi, K., Weiland, D., ... Wiesner, R. J. (2014). Mitochondrial Function in Murine Skin Epithelium is Crucial for Hair Follicle Morphogenesis and Epithelial-Mesenchymal Interactions. The Journal of Investigative Dermatology. DOI:10.1038/jid.2014.475
    . Publication link: 514369d4-3b86-467e-aa3e-df1d70fe8743
  • Paus, R., Langan, E. A., Vidali, S., Ramot, Y., & Andersen, B. (2014). Neuroendocrinology of the hair follicle: principles and clinical perspectives. Trends in Molecular Medicine. DOI:10.1016/j.molmed.2014.06.002
    . Publication link: 7992f16b-ff88-4a8a-a1b2-45b5097908b9
  • Paus, R., Wang, M., Yue, Z., & Ramot, Y. (2014). SIRT2 as a new player in epigenetic programming of keratinocyte differentiation and a candidate tumor suppressor. Experimental Dermatology (Online), 23(9), 636. DOI:10.1111/exd.12434
    . Publication link: cecfb59a-a8d5-4f7c-95a0-3efbb1a404e7
  • Paus, R., Xie, G., Wang, H., Yan, Z., Cai, L., Zhou, G., ... Yue, Z. (2014). Testing Chemotherapeutic Agents in the Feather Follicle Identifies a Selective Blockade of Cell Proliferation and a Key Role for Sonic Hedgehog Signaling in Chemotherapy-Induced Tissue Damage. Unknown Journal. DOI:10.1038/jid.2014.409
    . Publication link: a3c215fa-e2e0-4509-a0e8-6189bb5b9efb
  • Purba, T. S., Haslam, I. S., Poblet, E., Jiménez, F., Gandarillas, A., Izeta, A., & Paus, R. (2014). Human epithelial hair follicle stem cells and their progeny: Current state of knowledge, the widening gap in translational research and future challenges. BioEssays, 36(5), 513-525. DOI:10.1002/bies.201300166
    . Publication link: a82bdfb7-cedd-4f1c-994f-253d61d99dde
  • Ramot, Y., & Paus, R. (2014). Harnessing neuroendocrine controls of keratin expression: A new therapeutic strategy for skin diseases?. BioEssays, 36(7), 672-686. DOI:10.1002/bies.201400006
    . Publication link: a39dac89-0746-4b16-bb9a-fc384aba47a4
  • Ramot, Y., Mastrofrancesco, A., Herczeg-Lisztes, E., Bíró, T., Picardo, M., Kloepper, J. E., & Paus, R. (2014). Advanced inhibition of undesired human hair growth by pparγ modulation?. Journal of Investigative Dermatology, 134(4), 1128-1131. DOI:10.1038/jid.2013.473
    . Publication link: 403f1166-5b3a-49f4-9e56-b2a650f4e665
  • Rendl, M., Sundberg, J., Seykora, J., Luger, T., Paus, R., & Trier-Mork, T. (2014). Launch of the new letter category: 'Mouse Mutants with Absent/Minimal Skin Phenotype'. Experimental Dermatology, 23(10), 691. DOI:10.1111/exd.12307
    . Publication link: 5a577a4f-b4b1-4a1b-9643-221a664e25c7
  • Vidali, S., Knuever, J., Lerchner, J., Giesen, M., Bíró, T., Klinger, M., ... Paus, R. (2014). Hypothalamic-pituitary-thyroid axis hormones stimulate mitochondrial function and biogenesis in human hair follicles. Journal of Investigative Dermatology, 134(1), 33-42. DOI:10.1038/jid.2013.286
    . Publication link: d08ad642-f2d5-44bb-be87-3ab9e802cfa2

2013

  • Bertolini, M., Meyer, K. C., Slominski, R., Kobayashi, K., Ludwig, R. J., & Paus, R. (2013). The immune system of mouse vibrissae follicles: Cellular composition and indications of immune privilege. Experimental Dermatology, 22(9), 593-598. DOI:10.1111/exd.12205
    . Publication link: 1f2f016c-6547-46ea-917f-1b0952f4ba72
  • Duque-Estrada, B., Tosti, A., Mcelwee, K. J., Gilhar, A., Keren, A., Bertolini, M., ... Itami, S. (2013). What causes alopecia areata?: Section Editors: Ralf Paus, Manchester/Lübeck and Raymond Cho, San Francisco Controversies in Experimental Dermatology: What causes alopecia areata?. Experimental Dermatology, 22(9), 609-626. DOI:10.1111/exd.12209
    . Publication link: bd79182d-ffe5-4517-8e89-f9328e338239
  • Ernst, N., Yay, A., Bíró, T., Tiede, S., Humphries, M., Paus, R., & Kloepper, J. E. (2013). β1 integrin signaling maintains human epithelial progenitor cell survival in situ and controls proliferation, apoptosis and migration of their progeny. PLoS ONE, 8(12), [e84356]. DOI:10.1371/journal.pone.0084356
    . Publication link: 2bf0a17c-7f28-49c7-a363-5ddd30f0dfc1
  • Gilhar, A., Keren, A., & Paus, R. (2013). A new humanized mouse model for alopecia areata.The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research, 16(1), S37-38. DOI:10.1038/jidsymp.2013.11
    . Publication link: 5bcd3481-ad2d-409d-a222-d9d4d467bc64
  • Gilhar, A., Keren, A., Shemer, A., D'Ovidio, R., Ullmann, Y., & Paus, R. (2013). Autoimmune disease induction in a healthy human organ: A humanized mouse model of alopecia areata. Journal of Investigative Dermatology, 133(3), 844-847. DOI:10.1038/jid.2012.365
    . Publication link: da756b57-d5c2-4d5f-b0d8-0bf133e7301a
  • Gilhar, A., Keren, A., Shemer, A., Ullmann, Y., & Paus, R. (2013). Blocking potassium channels (Kv1.3): A new treatment option for alopecia areata?. Journal of Investigative Dermatology, 133(8), 2088-2091. DOI:10.1038/jid.2013.141
    . Publication link: cc2ed203-c5bb-4e13-80ef-7a2fa9702312
  • Harries, M. J., Meyer, K., Chaudhry, I., E Kloepper, J., Poblet, E., Griffiths, C. E. M., & Paus, R. (2013). Lichen planopilaris is characterized by immune privilege collapse of the hair follicle's epithelial stem cell niche. Journal of Pathology, 231(2), 236-247. DOI:10.1002/path.4233
    . Publication link: 3490f078-b943-4aa4-85b4-75bafcc92c8d | PubMed:23788005
  • Haslam, I. S., Pitre, A., Schuetz, J. D., & Paus, R. (2013). Protection against chemotherapy-induced alopecia: Targeting ATP-binding cassette transporters in the hair follicle?. Trends in Pharmacological Sciences, 34(11), 599-604. DOI:10.1016/j.tips.2013.09.001
    . Publication link: 1759efbf-6095-4495-828c-a7de18dae5ca
  • Hinde, E., Haslam, I. S., Schneider, M. R., Langan, E. A., Kloepper, J. E., Schramm, C., ... Paus, R. (2013). A practical guide for the study of human and murine sebaceous glands in situ. Experimental Dermatology (Online), 22(10), 631-637. DOI:10.1111/exd.12207
    . Publication link: c031fa9a-900a-4045-9af8-afea38e679f3
  • Ito, T., Bertolini, M., Funakoshi, A., Ito, N., Takayama, T., Biro, T., ... Tokura, Y. (2013). Birth, life, and death of the MAGE3 hypothesis of alopecia areata pathobiology. Journal of Dermatological Science, 72(3), 327-330. DOI:10.1016/j.jdermsci.2013.07.014
    . Publication link: 2c3a7fff-f180-41ec-a9f3-dba96da13f2f
  • Kloepper, J. E., Kawai, K., Bertolini, M., Kanekura, T., & Paus, R. (2013). Loss of γδ t cells results in hair cycling defects. Journal of Investigative Dermatology, 133(6), 1666-1669. DOI:10.1038/jid.2013.17
    . Publication link: a3c9f011-eb84-4ee2-ae19-e9ca9fc84405 | PubMed:23334345
  • Langan, E. A., Lisztes, E., Bíro, T., Funk, W., Kloepper, J. E., Griffiths, C. E. M., & Paus, R. (2013). Dopamine is a novel, direct inducer of catagen in human scalp hair follicles in vitro. British Journal of Dermatology, 168(3), 520-525. DOI:10.1111/bjd.12113
    . Publication link: a5cd7f75-fae6-408e-8715-36056771216b | PubMed:23176199
  • Langan, E. A., Vidali, S., Pigat, N., Funk, W., Lisztes, E., Bíró, T., ... Paus, R. (2013). Tumour Necrosis Factor Alpha, Interferon Gamma and Substance P Are Novel Modulators of Extrapituitary Prolactin Expression in Human Skin. PLoS ONE, 8(4), [e60819]. DOI:10.1371/journal.pone.0060819
    . Publication link: 4a1ccc0f-7879-43f4-912e-3992a75f859a | PubMed:23626671
  • Meier, N. T., Haslam, I. S., Pattwell, D. M., Zhang, G. Y., Emelianov, V., Paredes, R., ... Paus, R. (2013). Thyrotropin-releasing hormone (TRH) promotes wound re-epithelialisation in frog and human skin.PLoS ONE, 8(9), [e73596]. DOI:10.1371/journal.pone.0073596
    . Publication link: 594e6cfe-74ab-4886-b6c4-d0df4e87aeb5 | PubMed:24023889
  • Nakamura, M., Schneider, M. R., Schmidt-Ullrich, R., & Paus, R. (2013). Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and/or structure: An update. Journal of Dermatological Science, 69(1), 6-29. DOI:10.1016/j.jdermsci.2012.10.001
    . Publication link: 7551b52d-2fc1-4f38-8d60-ca7f7ea60164 | PubMed:23165165
  • Paus, R. (2013). Migrating melanocyte stem cells: Masters of disaster?. Nature Medicine, 19(7), 818-819. DOI:10.1038/nm.3264
    . Publication link: af23d7ce-dd12-4c6b-ab13-7f5d8c512c52
  • Paus, R., & Bertolini, M. (2013). The role of hair follicle immune privilege collapse in alopecia areata: status and perspectives.The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research, 16(1), S25-27. DOI:10.1038/jidsymp.2013.7
    . Publication link: 850b0e27-753f-47a8-b62d-92ebdf741af6
  • Paus, R., De Paus, R. A., Geilenkirchen, M. A., Van Riet, S., Van Dissel, J. T., & Van De Vosse, E. (2013). Differential expression and function of human IL-12Rβ2 polymorphic variants. Molecular Immunology, 56(4), 380-389. DOI:10.1016/j.molimm.2013.07.002
    . Publication link: 94b25899-5f38-4016-8dce-7a058b627e83
  • Paus, R., De Paus, R. A., Van Crevel, R., Van Beek, R., Sahiratmadja, E., Alisjahbana, B., ... Van De Vosse, E. (2013). The influence of influenza virus infections on the development of tuberculosis. Tuberculosis, 93(3), 338-342. DOI:10.1016/j.tube.2013.02.006
    . Publication link: 95b2b1d2-5dfa-41d5-908d-adf0a9e2757e
  • Paus, R., de Paus, R. A., van Wengen, A., Schmidt, I., Visser, M., Verdegaal, E. M. E., ... van de Vosse, E. (2013). Inhibition of the type I immune responses of human monocytes by IFN-α and IFN-β. Cytokine, 61(2), 645-655. DOI:10.1016/j.cyto.2012.12.005
    . Publication link: 4f68c5ea-d59b-4542-b958-206345687ad5
  • Paus, R., Haslam, I. S., Sharov, A. A., & Botchkarev, V. A. (2013). Pathobiology of chemotherapy-induced hair loss. Lancet Oncology, 14(2), e50-e59. DOI:10.1016/S1470-2045(12)70553-3
    . Publication link: f3822393-14c4-4f6c-a63d-74ae2d987bb7 | PubMed:23369683
  • Paus, R., van de Vosse, E., Haverkamp, M. H., Ramirez-Alejo, N., Martinez-Gallo, M., Blancas-Galicia, L., ... Bustamante, J. (2013). IL-12Rβ1 deficiency: Mutation update and description of the IL12RB1 variation database. Human Mutation, 34(10), 1329-1339. DOI:10.1002/humu.22380
    . Publication link: ffb2a48c-68c0-45db-98d9-8f6320cabc42
  • Rakers, S., Niklasson, L., Steinhagen, D., Kruse, C., Schauber, J., Sundell, K., & Paus, R. (2013). Antimicrobial peptides (AMPs) from fish epidermis: Perspectives for investigative dermatology. Journal of Investigative Dermatology, 133(5), 1140-1149. DOI:10.1038/jid.2012.503
    . Publication link: bbfc1b66-e34f-47dc-af29-d88898cfd00b | PubMed:23407389
  • Ramot, Y., Sugawara, K., Zákány, N., Tóth, B. I., Bíró, T., & Paus, R. (2013). A novel control of human keratin expression: Cannabinoid receptor 1-mediated signaling down-regulates the expression of keratins K6 and K16 in human keratinocytes in vitro and in situ. PeerJ, 2013(1), [e40]. DOI:10.7717/peerj.40
    . Publication link: 47f58b08-0573-496c-9bc2-3d15e9922611
  • Ramot, Y., Zhang, G., Bírõ, T., Langbein, L., & Paus, R. (2013). Is thyrotropin-releasing hormone a novel neuroendocrine modulator of keratin expression in human skin?. British Journal of Dermatology, 169(1), 146-151. DOI:10.1111/bjd.12264
    . Publication link: c8971ccc-01d1-46c5-8f8d-a4cfd7e640ef | PubMed:23373458
  • Samuelov, L., Sprecher, E., Sugawara, K., Singh, S. K., Tobin, D. J., Tsuruta, D., ... Paus, R. (2013). Topobiology of human pigmentation: P-cadherin selectively stimulates hair follicle melanogenesis. Journal of Investigative Dermatology, 133(6), 1591-1600. DOI:10.1038/jid.2013.18
    . Publication link: eb37c9bd-1e1d-4396-b9a5-241387d9ef87 | PubMed:23334344
  • Sugawara, K., Zákány, N., Hundt, T., Emelianov, V., Tsuruta, D., Schäfer, C., ... Paus, R. (2013). Cannabinoid receptor 1 controls human mucosal-type mast cell degranulation and maturation in situ. Journal of Allergy and Clinical Immunology, 132(1), 182-e8. DOI:10.1016/j.jaci.2013.01.002
    . Publication link: ef7639e2-195e-4bf4-a573-b02fd1768650 | PubMed:23453134
  • Syed, F., Bagabir, R. A., Paus, R., & Bayat, A. (2013). Ex vivo evaluation of antifibrotic compounds in skin scarring: EGCG and silencing of PAI-1 independently inhibit growth and induce keloid shrinkage. Laboratory Investigation, 93(8), 946-960. DOI:10.1038/labinvest.2013.82
    . Publication link: 3f942f4e-d018-4dcc-bbba-ac3c39d7f26f

2012

2011

  • Al-Nuaimi, Y., Kloepper, J., Watson, R. E. B., & Paus, R. (2011). Towards deciphering a gene signature of anagen vs catagen in human hair follicles. British Journal of Dermatology, 164(4), 930-930.
    . Publication link: 48dc68a7-3933-412a-a502-19fe6c02a253
  • Al-Nuaimi, Y., Paus, R., & Baier, G. (2011). Controlled switching between states of epithelial proliferation and apoptosis in a mathematical model of the human hair cycle. British Journal of Dermatology, 164(4), 915-915.
    . Publication link: b7bad1c5-a574-4ad5-b79a-c602a5555755
  • Ansell, D. M., Kloepper, J. E., Thomason, H. A., Paus, R., & Hardman, M. J. (2011). Exploring the hair growth-wound healing connection: Anagen phase promotes wound re-Epithelialization. Journal of Investigative Dermatology, 131(2), 518-528. DOI:10.1038/jid.2010.291
    . Publication link: 789f05ef-c298-4c8a-80a9-14f468706470 | PubMed:20927125
  • Bagabir, R. A., Syed, F., Paus, R., & Bayat, A. (2011). A NOVEL LONG-TERM HUMAN ORGAN CULTURE MODEL IN KELOID DISEASE DEMONSTRATES IN-SITU FUNCTIONAL ANALYSIS AND EVALUATES POTENTIAL THERAPEUTIC COMPOUNDS. Wound Repair and Regeneration, 19(2), A11-A11.
    . Publication link: c0931e9a-2422-4d16-be20-6f84e709ee4c
  • Bagabir, R. A., Syed, F., Rautemaa, R., McGrouther, D. A., Paus, R., & Bayat, A. (2011). UP-REGULATION OF TOLL-LIKE RECEPTORS (TLR) 6, 7 AND 8 IN KELOID SCARS: DOES KELOID DISEASE REFLECT AN ABNORMAL INNATE IMMUNE RESPONSE TO VIRAL INFECTION?. Wound Repair and Regeneration, 19(2), A11-A11.
    . Publication link: b42ce2a3-bedd-45ed-affd-49214168ab37
  • Baris, O. R., Klose, A., Kloepper, J. E., Weiland, D., Neuhaus, J. F. G., Schauen, M., ... Wiesner, R. J. (2011). The mitochondrial electron transport chain is dispensable for proliferation and differentiation of epidermal progenitor cells. Stem Cells, 29(9), 1459-1468. DOI:10.1002/stem.695
    . Publication link: 12f8e19b-3cec-4558-8fe7-54327bce6141 | PubMed:21780252
  • Borbíró, I., Lisztes, E., Tóth, B. I., Czifra, G., Oláh, A., Szöllsi, A. G., ... Bíró, T. (2011). Activation of transient receptor potential vanilloid-3 inhibits human hair growth. Journal of Investigative Dermatology, 131(8), 1605-1614. DOI:10.1038/jid.2011.122
    . Publication link: 3f2c8fa4-891a-4ad6-bf01-79a9ee95810c | PubMed:21593771
  • De Schellenberger, A. A., Horland, R., Rosowski, M., Paus, R., Lauster, R., & Lindner, G. (2011). Cartilage oligomeric matrix protein (COMP) forms part of the connective tissue of normal human hair follicles. Experimental Dermatology, 20(4), 361-366. DOI:10.1111/j.1600-0625.2010.01217.x
    . Publication link: 27a3aac5-5d43-45a6-ab8c-215ba99c6308 | PubMed:21355885
  • Duheron, V., Amoasii, L., Decossas, M., Paus, R., & Mueller, C. G. (2011). HAIR FOLLICLE RANK-LIGAND REGULATES EPITHELIAL GROWTH VIA BCL-3. ADVANCES IN TNF FAMILY RESEARCH, 691, 644-645.
    . Publication link: bbf05d91-c275-4306-9cff-1403799a9663
  • Duheron, V., Hess, E., Duval, M., Decossas, M., Castaned, B., Klöpper, J. E., ... Mueller, C. G. (2011). Receptor activator of NF-κB (RANK) stimulates the proliferation of epithelial cells of the epidermo-pilosebaceous unit. Proceedings of the National Academy of Sciences of the United States of America, 108(13), 5342-5347. DOI:10.1073/pnas.1013054108
    . Publication link: 2460bb75-3f24-4e2e-9bca-7e9983cbadfa | PubMed:21402940
  • Ernst, N., Tiede, S., Humphries, M., Paus, R., & Klopper, J. E. (2011). The impact of beta1 integrin signalling on adult human hair follicle epithelial progenitor cell viability. EXPERIMENTAL DERMATOLOGY, 20(2), 208-208.
    . Publication link: 95903638-ad71-40c5-8438-32f703fddd88
  • Flori, E., Mastrofrancesco, A., Kovacs, D., Ramot, Y., Briganti, S., Bellei, B., ... Picardo, M. (2011). 2,4,6-Octatrienoic acid is a novel promoter of melanogenesis and antioxidant defence in normal human melanocytes via PPAR-γ activation. Pigment Cell and Melanoma Research, 24(4), 618-630. DOI:10.1111/j.1755-148X.2011.00887.x
    . Publication link: 6c92a9d1-f7df-4398-b784-b6b6a3560463 | PubMed:21762468
  • Gáspár, E., Nguyen-Thi, K. T., Hardenbicker, C., Tiede, S., Plate, C., Bodó, E., ... Paus, R. (2011). Thyrotropin-releasing hormone selectively stimulates human hair follicle pigmentation. Journal of Investigative Dermatology, 131(12), 2368-2377. DOI:10.1038/jid.2011.221
    . Publication link: 87af4587-7f29-47ae-a373-510b60530028 | PubMed:21956127
  • Hindocha, S., Iqbal, S. A., Farhatullah, S., Paus, R., & Bayat, A. (2011). Characterization of stem cells in Dupuytren's disease. British Journal of Surgery, 98(2), 308-315. DOI:10.1002/bjs.7307
    . Publication link: a4d64dda-2fbc-4eb2-bc56-2eef00362882 | PubMed:21104823
  • Kinori, M., Kloepper, J. E., & Paus, R. (2011). Can the hair follicle become a model for studying selected aspects of human ocular immune privilege?. Investigative Ophthalmology and Visual Science, 52(7), 4447-4458. DOI:10.1167/iovs.10-7154
    . Publication link: 00b500dc-4d6c-4df7-b2f3-81657688971b | PubMed:21700717
  • Knuver, J., Vidali, S., Poeggeler, B., Gspr, E., Br, T., Tth, B. I., ... Paus, R. (2011). Neuroendocrine control of mitochondrial function in human epidermis and hair follicles. EXPERIMENTAL DERMATOLOGY, 20(2), 169-169.
    . Publication link: cc1466df-4a01-459b-8e85-516c629cb249
  • Langan, E. A., Griffiths, C. E. M., & Paus, R. (2011). In search of the source of hyperprolactinaemia in systemic lupus erythematosus. Clinical and Experimental Rheumatology, 29(6), 1060.
    . Publication link: 36aecaa4-e5b1-45cb-9ab7-886ac796f56e | PubMed:22032729
  • Lau, K., Hedegaard, M. A. B., Kloepper, J. E., Paus, R., Wood, B. R., & Deckert, V. (2011). Visualization and characterisation of defined hair follicle compartments by Fourier transform infrared (FTIR) imaging without labelling. Journal of Dermatological Science, 63(3), 191-198. DOI:10.1016/j.jdermsci.2011.05.002
    . Publication link: 50188914-f65e-424e-8272-b12718af90db | PubMed:21752602
  • Mardaryev, A. N., Meier, N., Poterlowicz, K., Sharov, A. A., Sharova, T. Y., Ahmed, M. I., ... Botchkarev, V. A. (2011). Lhx2 differentially regulates Sox9, Tcf4 and Lgr5 in hair follicle stem cells to promote epidermal regeneration after injury. Development, 138(22), 4843-4852. DOI:10.1242/dev.070284
    . Publication link: 7751e8c4-422d-4bff-8b24-3dbee1be074d | PubMed:22028024
  • Meier, N. T., Zhang, G., Schafer, T., Geissen, M., Emelianov, V., Kleinspehn, E., ... Paus, R. (2011). An in vitro test system to study human epidermal wound healing in situ. EXPERIMENTAL DERMATOLOGY, 20(2), 168-168.
    . Publication link: bac954d1-5ddb-4e78-a4ed-6c8d4e10737b
  • Paus, R. (2011). A neuroendocrinological perspective on human hair follicle pigmentation. Pigment Cell and Melanoma Research, 24(1), 89-106. DOI:10.1111/j.1755-148X.2010.00808.x
    . Publication link: f67173d9-26b2-421e-b054-4a225749d7dd | PubMed:21108769
  • Ramot, Y., Tiede, S., Bíró, T., Bakar, M. H. A., Sugawara, K., Philpott, M. P., ... Paus, R. (2011). Spermidine promotes human hair growth and is a novel modulator of human epithelial stem cell functions. PLoS ONE, 6(7), [e22564]. DOI:10.1371/journal.pone.0022564
    . Publication link: 2541fcba-90c1-4cb7-ac39-91cd8e2ffb94 | PubMed:21818338
  • Sebastian, A., Syed, F., McGrouther, D. A., Colthurst, J., Paus, R., & Bayat, A. (2011). A novel in vitro assay for electrophysiological research on human skin fibroblasts: Degenerate electrical waves downregulate collagen I expression in keloid fibroblasts. Experimental Dermatology, 20(1), 64-68. DOI:10.1111/j.1600-0625.2010.01150.x
    . Publication link: d5065bdd-986d-4a28-9c03-102d544e5fdc | PubMed:20707813
  • Sugawara, K., Br, T., Kromminga, A., Tsuruta, D., Tth, B. I., Zimmer, A., ... Paus, R. (2011). Tonic inhibitory effects of endocannabinoids on human skin mast cellfunctions in situ by cannabinoid receptor 1 (CB1)-mediated signalling. EXPERIMENTAL DERMATOLOGY, 20(2), 168-168.
    . Publication link: 7d263e2d-b17b-4436-ba78-141620dde82e
  • Sugawara, K., Dahlhoff, M., Paus, R., & Schneider, M. R. (2011). Increased EGFR activity induces epidermal thickening and retards the initiation of hair follicle cycling in Dsk5 mice. EXPERIMENTAL DERMATOLOGY, 20(2), 205-205.
    . Publication link: d0be6bbd-37aa-4adc-b091-4ab684015c15
  • Tiede, S., Keckeis, P., Petschnik, A., Kruse, C., & Paus, R. (2011). Functional importance and hormonal regulation of nestin expression in multi potent adult human skin progenitor cells in situ and in vitro. EXPERIMENTAL DERMATOLOGY, 20(2), 205-205.
    . Publication link: cea570e9-883c-45d9-867f-88b650e03531
  • Tóth, B. I., Dobrosi, N., Dajnoki, A., Czifra, G., Oláh, A., Szöllsi, A. G., ... Bíró, T. (2011). Endocannabinoids modulate human epidermal keratinocyte proliferation and survival via the sequential engagement of cannabinoid receptor-1 and transient receptor potential vanilloid-1. Journal of Investigative Dermatology, 131(5), 1095-1104. DOI:10.1038/jid.2010.421
    . Publication link: 9c08c483-b11c-476d-b8b5-b59184247569 | PubMed:21248768

2010

  • Anderson, J. R., Zorbas, J. S., Phillips, J. K., Harrison, J. L., Dawson, L. F., Bolt, S. E., ... Fear, M. W. (2010). Systemic decreases in cutaneous innervation after burn injury. Journal of Investigative Dermatology, 130(7), 1948-1951. DOI:10.1038/jid.2010.47
    . Publication link: 3a1374da-200a-49fc-af1f-a419005e7706 | PubMed:20336082
  • Arck, P., Handjiski, B., Hagen, E., Pincus, M., Bruenahl, C., Bienenstock, J., & Paus, R. (2010). Is there a 'gut-brain-skin axis'?. Experimental Dermatology, 19(5), 401-405. DOI:10.1111/j.1600-0625.2009.01060.x
    . Publication link: e3c292de-6ad2-425b-bf70-9ea74917c2db | PubMed:20113345
  • Bodó, E., Kany, B., Gáspár, E., Knüver, J., Kromminga, A., Ramot, Y., ... Paus, R. (2010). Thyroid-stimulating hormone, a novel, locally produced modulator of human epidermal functions, is regulated by thyrotropin-releasing hormone and thyroid hormones. Endocrinology, 151(4), 1633-1642. DOI:10.1210/en.2009-0306
    . Publication link: 1e556be1-261f-40d6-a321-ce4be3c2b792 | PubMed:20176727
  • Bodó, E., Wiersma, F., Funk, W., Kromminga, A., Jelkmann, W., & Paus, R. (2010). Does erythropoietin modulate human hair follicle melanocyte activities in situ?. Experimental Dermatology, 19(1), 65-67. DOI:10.1111/j.1600-0625.2009.00938.x
    . Publication link: 90ab4c36-fae4-47cf-91c0-c4569d2a29c7 | PubMed:19645852
  • Brosh, R., Sarig, R., Natan, E. B., Molchadsky, A., Madar, S., Bornstein, C., ... Rotter, V. (2010). P53-dependent transcriptional regulation of EDA2R and its involvement in chemotherapy-induced hair loss. FEBS Letters, 584(11), 2473-2477. DOI:10.1016/j.febslet.2010.04.058
    . Publication link: 46bbe642-b5c8-4e16-bfdb-225852849a96 | PubMed:20434500
  • Bundy, C., Griffiths, C., Paus, R., & Harries, M. (2010). Illness perception, psychological distress and quality of life in patients with cicatricial alopecias. Journal of Investigative dermatology, 130, S67-S67.
    . Publication link: 6a17bef1-b426-451f-b579-82b2bcc43182
  • Ernst, N., Tiede, S., Tronnier, V., Kruse, C., Zechel, C., & Paus, R. (2010). An improved, standardised protocol for the isolation, enrichment and targeted neural differentiation of Nestin+ progenitors from adult human dermis. Experimental Dermatology, 19(6), 549-555. DOI:10.1111/j.1600-0625.2009.01041.x
    . Publication link: f116bcb2-94b5-4fcb-a228-d3a45e4d695c
  • Farman, N., Maubec, E., Poeggeler, B., Klatte, J. E., Jaisser, F., & Paus, R. (2010). The mineralocorticoid receptor as a novel player in skin biology: Beyond the renal horizon?. Experimental Dermatology, 19(2), 100-107. DOI:10.1111/j.1600-0625.2009.01011.x
    . Publication link: 8717739b-9309-429c-b837-ad2b2fff7de1 | PubMed:19925636
  • Fleger-Weckmann, A., Kloepper, J. E., Bechtel, M., Chen, Z. L., Langbein, L., Bloch, W., ... Nischt, R. (2010). The role of gamma l chain containing laminins for the formation and function of the dermo-epidermal basement membrane. Journal of Investigative dermatology, 130, S90-S90.
    . Publication link: 4d072e8d-86d2-4448-9d11-7e33e682e0b7
  • Gáspár, E., Hardenbicker, C., Bodó, E., Wenzel, B., Ramot, Y., Funk, W., ... Paus, R. (2010). Thyrotropin releasing hormone (TRH): A new player in human hair-growth control. FASEB Journal, 24(2), 393-403. DOI:10.1096/fj.08-126417
    . Publication link: b671ba58-8576-4eee-8734-bb81420f164c
  • Harries, M. J., & Paus, R. (2010). The pathogenesis of primary cicatricial alopecias. American Journal of Pathology, 177(5), 2152-2162. DOI:10.2353/ajpath.2010.100454
    . Publication link: 10e9359c-e93c-41d4-80e9-e6193a385142 | PubMed:20889564
  • Harries, M. J., Chaudhry, I. H., Paus, R., & Griffiths, C. E. M. (2010). Cicatricial alopecias: a retrospective analysis of 92 cases from one U.K. centre. British Journal of Dermatology, 163, 43-44.
    . Publication link: 17d2afd9-a69e-4f82-993a-899756afc0a5
  • Harries, M. J., Sun, J., Paus, R., & King, L. E. (2010). Management of alopecia areata. BMJ, 341(7766), 242-246. [c3671]. DOI:10.1136/bmj.c3671
    . Publication link: 7cdae5e3-6cab-4cbe-9213-381e9d39ed0a | PubMed:20656774
  • Harries, M., Griffiths, C., & Paus, R. (2010). Immunopathology of "neutrophilic" primary cicatricial alopecias. Journal of Investigative dermatology, 130, S15-S15.
    . Publication link: 917fde17-b19b-4c0e-a16d-14efd6b2737e
  • Hoi, C. S. L., Lee, S. E., Lu, S. Y., McDermitt, D. J., Osorio, K. M., Piskun, C. M., ... Tumbar, T. (2010). Runx1 directly promotes proliferation of hair follicle stem cells and epithelial tumor formation in mouse skin. Molecular and Cellular Biology, 30(10), 2518-2536. DOI:10.1128/MCB.01308-09
    . Publication link: 5b09f0c6-9280-4c54-b101-74aa0720d32d | PubMed:20308320
  • Holub, B. S., Kloepper, J. E., Rauch, I., Kofler, B., & Paus, R. (2010). GALANIN INHIBITS HAIR FOLLICLE GROWTH. NEUROPEPTIDES, 44(6), 541-541.
    . Publication link: 88f87ffc-7084-4130-8cc1-248641e7a546
  • Imanishi, H., Tsuruta, D., Tateishi, C., Sugawara, K., Paus, R., Tsuji, T., ... Kobayashi, H. (2010). Erratum to Laminin-511, inducer of hair growth, is down-regulated and its suppressor in hair growth, laminin-332 up-regulated in chemotherapy-induced alopecia. Journal of Dermatological Science, 60(1), 58. DOI:10.1016/j.jdermsci.2010.08.001
    . Publication link: 597f7f2c-b2b7-49d2-8cb3-89341cba227e
  • Imanishi, H., Tsuruta, D., Tateishi, C., Sugawara, K., Paus, R., Tsuji, T., ... Kobayashi, H. (2010). Laminin-511, inducer of hair growth, is down-regulated and its suppressor in hair growth, laminin-332 up-regulated in chemotherapy-induced alopecia. Journal of Dermatological Science, 58(1), 43-54. DOI:10.1016/j.jdermsci.2010.02.005
    . Publication link: fc964374-e1f2-4693-b7ad-fc3cd7740048 | PubMed:20211547
  • Iqbal, S. A., Syed, F., McGrouther, D. A., Paus, R., & Bayat, A. (2010). Differential distribution of haematopoietic and nonhaematopoietic progenitor cells in intralesional and extralesional keloid: Do keloid scars provide a niche for nonhaematopoietic mesenchymal stem cells?. British Journal of Dermatology, 162(6), 1377-1383. DOI:10.1111/j.1365-2133.2010.09738.x
    . Publication link: cee2ff89-b1a8-4ad5-8646-33b72ce2d0d2 | PubMed:20192956
  • Ito, N., Sugawara, K., Bodó, E., Takigawa, M., Van Beek, N., Ito, T., & Paus, R. (2010). Corticotropin-releasing hormone stimulates the in situ generation of mast cells from precursors in the human hair follicle mesenchyme. Journal of Investigative Dermatology, 130(4), 995-1004. DOI:10.1038/jid.2009.387
    . Publication link: d2c3cc7e-01c3-48ad-b3f2-d61b4e71088b | PubMed:20043013
  • Kaufman, G., d'Ovidio, R., Kaldawy, A., Assy, B., Ullmann, Y., Etzioni, A., ... Gilhar, A. (2010). An unexpected twist in alopecia areata pathogenesis: Are NK cells protective and CD49b+ T cells pathogenic?. Experimental Dermatology, 19(8), e347-e349. DOI:10.1111/j.1600-0625.2010.01106.x
    . Publication link: 6571e93a-4f46-41e4-abeb-dd8225a78e5c
  • Kloepper, J. E., Bíró, T., Paus, R., & Cseresnyés, Z. (2010). Point scanning confocal microscopy facilitates 3D human hair follicle imaging in tissue sections. Experimental Dermatology, 19(7), 691-694. DOI:10.1111/j.1600-0625.2010.01110.x
    . Publication link: 5e50b9e7-143f-4550-9bcd-c9f268db6158 | PubMed:20545762
  • Kloepper, J. E., Sugawara, K., Al-Nuaimi, Y., Gáspár, E., van Beek, N., & Paus, R. (2010). Methods in hair research: how to objectively distinguish between anagen and catagen in human hair follicle organ culture. Experimental Dermatology, 19(3), 305-312. DOI:10.1111/j.1600-0625.2009.00939.x
    . Publication link: dbda9030-adc5-47d3-bc66-776bc0bef8c4 | PubMed:19725870
  • Knuever, J., Poeggeler, B., Gaspar, E., Biro, T., Toth, B., Hellwig-Buergel, T., ... Paus, R. (2010). Thyrotropin-releasing hormone (TRH) controls mitochondrial function and biogenesis in human keratinocytes in situ. Journal of Investigative dermatology, 130, S20-S20.
    . Publication link: da582cc4-b69e-4f97-bb23-8f9d289567e7
  • Langan, E. A., & Paus, R. (2010). Female pattern hair loss: Beyond an androgenic aetiology?. British Journal of Dermatology, 163(5), 1140-1141. DOI:10.1111/j.1365-2133.2010.09955.x
    . Publication link: 96fa8b48-4a4f-4aed-a5e1-4a087dcc1548
  • Langan, E. A., Foitzik-Lau, K., Goffin, V., Ramot, Y., & Paus, R. (2010). Prolactin: An emerging force along the cutaneous-endocrine axis. Trends in Endocrinology and Metabolism, 21(9), 569-577. DOI:10.1016/j.tem.2010.06.001
    . Publication link: e199c242-2a01-4705-ba8e-6a5d8b68c114 | PubMed:20598901
  • Langan, E. A., Ramot, Y., Goffin, V., Griffiths, C. E. M., Foitzik, K., & Paus, R. (2010). Mind the (Gender) Gap: Does prolactin exert gender and/or site-specific effects on the human hair follicle. Journal of Investigative Dermatology, 130(3), 886-891. DOI:10.1038/jid.2009.340
    . Publication link: 62b82856-78d0-47e3-8b8e-df0d250dfc85
  • Langan, E. A., Ramot, Y., Hanning, A., Poeggeler, B., Bíró, T., Gaspar, E., ... Paus, R. (2010). Thyrotropin-releasing hormone and oestrogen differentially regulate prolactin and prolactin receptor expression in female human skin and hair follicles in vitro. British Journal of Dermatology, 162(5), 1127-1131. DOI:10.1111/j.1365-2133.2010.09676.x
    . Publication link: 2367930e-6ca2-412b-82a4-7ce290911d1b | PubMed:20302576
  • Lau, K., Matthaeus, C., Popp, J., Wood, B. R., Kloepper, J. E., Paus, R., & Deckert, V. (2010). Label-free non-destructive identification of stem cells in the hair follicle with confocal Raman spectrocopy. AIP Conference Proceedings, 1267, 360-361. DOI:10.1063/1.3482558
    . Publication link: bfdcac13-c862-473f-aadf-a3f142062585
  • Lefever, T., Pedersen, E., Basse, A., Paus, R., Quondamatteo, F., Stanley, A. C., ... Brakebusch, C. (2010). N-WASP is a novel regulator of hair-follicle cycling that controls antiproliferative TGFβ pathways. Journal of Cell Science, 123(1), 128-140. DOI:10.1242/jcs.053835
    . Publication link: 402cedc9-7aca-4d44-9784-6202042ee92e | PubMed:20016073
  • Lyne, L., Harries, M. J., Chaudhry, I. H., Farjo, B., Farjo, N., de Farias, D. C., ... Paus, R. (2010). Lichen planopilaris following hair transplantation and facelift surgery. British Journal of Dermatology, 163, 31-31.
    . Publication link: 3661d235-8d8a-49ff-9bce-2f665c20dfbc
  • Meier, N., Pattwell, D., Zhang, G. Y., Loconto, J., Geissen, M., Schafer, T., ... Paus, R. (2010). Novel neuroendocrine controls of amphibian and human skin reepithelialisation through thyrotropin-releasing hormone (TRH) and bombesin and its mammalian homologues. Journal of Investigative dermatology, 130, S88-S88.
    . Publication link: ea04d524-885b-4b73-853b-d0a4e0d06456
  • Meyer, K. C., Tiede, S., Harries, M. J., Kloepper, J. E., & Paus, R. (2010). IFN-gamma induces bulge immunoprivilege collapse and may cause epithelial stem cell exhaust. Journal of Investigative dermatology, 130, S42-S42.
    . Publication link: 6dd1ae61-ee9c-4f40-82ca-f2b2a6bbf575
  • Ohyama, M., Zheng, Y., Paus, R., & Stenn, K. S. (2010). The mesenchymal component of hair follicle neogenesis: Background, methods and molecular characterization. Experimental Dermatology, 19(2), 89-99. DOI:10.1111/j.1600-0625.2009.00935.x
    . Publication link: bc57b1c0-cd9e-4387-8a1b-11cf19652556 | PubMed:19650868
  • Paus, R. (2010). Exploring the thyroid-skin connection: Concepts, questions, and clinical relevance. Journal of Investigative Dermatology, 130(1), 7-10. DOI:10.1038/jid.2009.359
    . Publication link: 06d40021-ba2d-45d8-a9d9-c35dd27f6cef | PubMed:20010860
  • Paus, R. (2010). Neuroendocrinology of the hair follicle: A hitchhiker's guide through the skin galaxy. EXPERIMENTAL DERMATOLOGY, 19(6), 557-557.
    . Publication link: 2ef19370-cbbd-4ef3-97f8-8c5f8d4b46e6
  • Paus, R., Harries, M. J., Meyer, K. C., Chaudhry, I. H., & Griffiths, C. E. (2010). Does collapse of immune privilege in the hair follicle bulge play a role in the pathegenesis of primary cicatricial alopecia?. Clin Exp Dermatol., 35(6), 637-44.
    . Publication link: c2d86d30-befe-460a-96aa-18ae9e8735f3
  • Paus, R., Van De Vosse, E., Ottenhoff, T. H. M., De Paus, R. A., Verhard, E. M., De Boer, T., ... Kuijpers, T. W. (2010). Mycobacterium bovis BCG-itis and cervical lymphadenitis due to salmonella enteritidis in a patient with complete interleukin-12/-23 receptor β1 deficiency. Infection, 38(2), 128-130. DOI:10.1007/s15010-009-9222-0
    . Publication link: fa1edd6b-949c-4aef-b5d4-8a509e713c82 | PubMed:20213287
  • Petschnik, A. E., Klatte, J. E., Evers, L. H., Kruse, C., Paus, R., & Danner, S. (2010). Phenotypic indications that human sweat glands are a rich source of nestin-positive stem cell populations. British Journal of Dermatology, 162(2), 380-383. DOI:10.1111/j.1365-2133.2009.09512.x
    . Publication link: 72703504-a980-48d3-82d1-e04b0aca1bec | PubMed:19772523
  • Petukhova, L., Duvic, M., Hordinsky, M., Norris, D., Price, V., Shimomura, Y., ... Christiano, A. M. (2010). Genome-wide association study in alopecia areata implicates both innate and adaptive immunity. Nature, 466(7302), 113-117. DOI:10.1038/nature09114
    . Publication link: d12727d8-49f4-4dbb-9d0d-ecedb6d24a29 | PubMed:20596022
  • Poeggeler, B., Bodó, E., Nadrowitz, R., Dunst, J., & Paus, R. (2010). A simple assay for the study of human hair follicle damage induced by ionizing irradiation. Experimental Dermatology, 19(8), e306-e309. DOI:10.1111/j.1600-0625.2009.01009.x
    . Publication link: 40ab1d8d-53a2-4a4a-ac62-d4f32f35aabc | PubMed:19925637
  • Poeggeler, B., Knuever, J., Gáspár, E., Bíró, T., Klinger, M., Bodó, E., ... Paus, R. (2010). Thyrotropin powers human mitochondria. FASEB Journal, 24(5), 1525-1531. DOI:10.1096/fj.09-147728
    . Publication link: a5d0106d-b45d-4bdc-aad1-91799a2f59ab | PubMed:20075194
  • Poeggeler, B., Schulz, C., Pappolla, M. A., Bodó, E., Tiede, S., Lehnert, H., & Paus, R. (2010). Leptin and the skin: A new frontier. Experimental Dermatology, 19(1), 12-18. DOI:10.1111/j.1600-0625.2009.00930.x
    . Publication link: df82036b-56bc-4f80-8787-9766bc3c20f9 | PubMed:19601981
  • Rakers, S., Gebert, M., Uppalapati, S., Meyer, W., Maderson, P., Sell, A. F., ... Paus, R. (2010). 'Fish matters': The relevance of fish skin biology to investigative dermatology. Experimental Dermatology, 19(4), 313-324. DOI:10.1111/j.1600-0625.2009.01059.x
    . Publication link: d2800768-a641-4385-bf11-908432660e0a | PubMed:20158518
  • Ramot, Y., Bíró, T., Tiede, S., Tóth, B. I., Langan, E. A., Sugawara, K., ... Paus, R. (2010). Prolactin - A novel neuroendocrine regulator of human keratin expression in situ. FASEB Journal, 24(6), 1768-1779. DOI:10.1096/fj.09-146415
    . Publication link: eae4c451-5400-4a59-a5de-c7957377dc48 | PubMed:20103718
  • Ramot, Y., Pietilä, M., Giuliani, G., Rinaldi, F., Alhonen, L., & Paus, R. (2010). Polyamines and hair: a couple in search of perfection. Experimental Dermatology, 19(9), 784-790. DOI:10.1111/j.1600-0625.2010.01111.x
    . Publication link: 3e1b1a6e-82a6-4e96-832b-a0432a2a6d59 | PubMed:20629736
  • Sayama, K., Kajiya, K., Sugawara, K., Sato, S., Hirakawa, S., Shirakata, Y., ... Hashimoto, K. (2010). Inflammatory Mediator TAK1 Regulates Hair Follicle Morphogenesis And Anagen Induction Shown By Using Keratinocyte-Specific TAK1-Deficient Mice. PLoS ONE, 5(6), [e11275]. DOI:10.1371/journal.pone.0011275
    . Publication link: 6a039890-2400-400a-9dbb-cd3b3bf12fb1 | PubMed:20585657
  • Schneider, M. R., & Paus, R. (2010). Sebocytes, multifaceted epithelial cells: Lipid production and holocrine secretion. International Journal of Biochemistry and Cell Biology, 42(2), 181-185. DOI:10.1016/j.biocel.2009.11.017
    . Publication link: 43da403e-0049-4227-8c8f-2d5eb6f9b88f | PubMed:19944183
  • Seeliger, S., Buddenkotte, J., Schmidt-Choudhury, A., Rosignoli, C., Shpacovitch, V., Von Arnim, U., ... Steinhoff, M. (2010). Pituitary adenylate cyclase activating polypeptide: An important vascular regulator in human skin in vivo. American Journal of Pathology, 177(5), 2563-2575. DOI:10.2353/ajpath.2010.090941
    . Publication link: 53a9d659-afcd-488c-b5e1-51480a063ff0 | PubMed:20889562
  • Sugawara, K., Hundt, T., Emelianov, V., Koennecke, M., Wollenberg, B., & Paus, R. (2010). Human skin and hair follicle versus nasal polyp organ culture as clinically and physiologically relevant model systems for studying normal human connective tissue-type and mucosal-type mast cell biology in situ. Journal of Investigative dermatology, 130, S43-S43.
    . Publication link: 10a542f2-ab38-4755-b5ae-e3888fc1f691
  • Sugawara, K., Schneider, M. R., Dahlhoff, M., Kloepper, J. E., & Paus, R. (2010). Cutaneous consequences of inhibiting EGF receptor signaling in vivo: Normal hair follicle development, but retarded hair cycle induction and inhibition of adipocyte growth in EgfrWa5 mice. Journal of Dermatological Science, 57(3), 155-161. DOI:10.1016/j.jdermsci.2009.12.004
    . Publication link: 8ca6e335-a385-4b00-8881-b080061f4f24 | PubMed:20060271
  • Tauchi, M., Fuchs, T. A., Kellenberger, A. J., Woodward, D. F., Paus, R., & Lütjen-Drecoll, E. (2010). Characterization of an in vivo model for the study of eyelash biology and trichomegaly: Mouse eyelash morphology, development, growth cycle, and anagen prolongation by bimatoprost. British Journal of Dermatology, 162(6), 1186-1197. DOI:10.1111/j.1365-2133.2010.09685.x
    . Publication link: 607702f5-0a12-4f4c-b31b-b12c5cbdccdf | PubMed:20346040
  • Thiryayi, S. A., Harries, M. J., White, E., Griffiths, C. E. M., Paus, R., & Chaudhry, I. H. (2010). Histopathological review of 78 cases of cicatricial alopecia at one U. K. centre. British Journal of Dermatology, 163, 93-94.
    . Publication link: 563033db-0305-4953-927a-0944c8c2bdb8
  • Tiede, S., Bohm, K., Meier, N., Funk, W., & Paus, R. (2010). Endocrine controls of primary adult human stem cell biology: Thyroid hormones stimulate keratin 15 expression, apoptosis, and differentiation in human hair follicle epithelial stem cells in situ and in vitro. European Journal of Cell Biology, 89(10), 769-777. DOI:10.1016/j.ejcb.2010.06.002
    . Publication link: a9972f90-adec-4444-b22e-8c71692d7abb | PubMed:20656376
  • Tiede, S., Plate, C., Meier, N., Abu Bakar, M. H., & Paus, R. (2010). Vitamin-D3 modulates human hair follicle epithelial progenitor cells in situ and in vitro. Journal of Investigative dermatology, 130, S89-S89.
    . Publication link: 410e9142-e0b6-461e-9ae3-29d347b6b742
  • Pattwell, D. M., Lynaugh, K. J., Watson, R. E. B., & Paus, R. (2010). HaCaT keratinocytes express functional receptors for thyroid-stimulating hormone. Journal of Dermatological Science, 59(1), 52-55. DOI:10.1016/j.jdermsci.2010.04.007
    . Publication link: a1896c3f-c289-4fb8-b8d5-8176e75f42d6
  • Pincus, M., Keil, T., Rücke, M., Bruenahl, C., Magdorf, K., Klapp, B. F., ... Arck, P. (2010). Fetal origin of atopic dermatitis. Journal of Allergy and Clinical Immunology, 125(1-3), 273-e4. DOI:10.1016/j.jaci.2009.10.057
    . Publication link: 97300b1b-e770-480f-9b4d-06315eccd775

2009

  • Antsiferova, M., Klatte, J. E., Bodó, E., Paus, R., Jorcano, J. L., Matzuk, M. M., ... Kögel, H. (2009). Keratinocyte-derived follistatin regulates epidermal homeostasis and wound repair. Laboratory Investigation, 89(2), 131-141. DOI:10.1038/labinvest.2008.120
    . Publication link: a686862d-b911-409e-b57f-c3fd68e5b9e9
  • Bíró, T., Tóth, B. I., Haskó, G., Paus, R., & Pacher, P. (2009). The endocannabinoid system of the skin in health and disease: novel perspectives and therapeutic opportunities. Trends in Pharmacological Sciences, 30(8), 411-420. DOI:10.1016/j.tips.2009.05.004
    . Publication link: 53bce729-d1fb-468f-b9a9-7d5fe85e24e4 | PubMed:19608284
  • Bodó, E., Kromminga, A., Bíró, T., Borbíró, I., Gáspár, E., Zmijewski, M. A., ... Paus, R. (2009). Human female hair follicles are a direct, nonclassical target for thyroid-stimulating hormone. Journal of Investigative Dermatology, 129(5), 1126-1139. DOI:10.1038/jid.2008.361
    . Publication link: 2990896b-f89d-407d-8230-7023b18af841
  • Bodó, E., Van Beek, N., Naumann, V., Ohnemus, U., Brzoska, T., Abels, C., & Paus, R. (2009). Modulation of chemotherapy-induced human hair follicle damage by 17-β estradiol and prednisolone: Potential stimulators of normal hair regrowth by "dystrophic catagen" promotion?. Journal of Investigative Dermatology, 129(2), 506-509. DOI:10.1038/jid.2008.228
    . Publication link: 9b6e4684-231e-4785-8d94-3bd4c7cc14ff
  • Foitzik, K., Langan, E. A., & Paus, R. (2009). Prolactin and the skin: A dermatological perspective on an ancient pleiotropic peptide hormone. Journal of Investigative Dermatology, 129(5), 1071-1087. DOI:10.1038/jid.2008.348
    . Publication link: dbbd879f-6520-47df-850e-81adc5f15126
  • Harries, M. J., Meyer, K. C., & Paus, R. (2009). Hair loss as a result of cutaneous autoimmunity: Frontiers in the immunopathogenesis of primary cicatricial alopecia. Autoimmunity Reviews, 8(6), 478-483. DOI:10.1016/j.autrev.2008.09.003
    . Publication link: ca4fa614-201c-46ea-8e73-53f5cffdbacb
  • Harries, M. J., Trueb, R. M., Tosti, A., Messenger, A. G., Chaudhry, I., Whiting, D. A., ... Paus, R. (2009). How not to get scar(r)ed: Pointers to the correct diagnosis in patients with suspected primary cicatricial alopecia. British Journal of Dermatology, 160(3), 482-501. DOI:10.1111/j.1365-2133.2008.09008.x
    . Publication link: db8d0f37-4820-421a-8c47-af9a9762b233 | PubMed:19183169
  • Havlickova, B., Bíró, T., Mescalchin, A., Tschirschmann, M., Mollenkopf, H., Bettermann, A., ... Paus, R. (2009). A human folliculoid microsphere assay for exploring epithelial- mesenchymal interactions in the human hair follicle. Journal of Investigative Dermatology, 129(4), 972-983. DOI:10.1038/jid.2008.315
    . Publication link: c59d5d48-6ccc-4223-9517-ae8b33ffc904
  • Lau, K., Paus, R., Tiede, S., Day, P., & Bayat, A. (2009). Exploring the role of stem cells in cutaneous wound healing. Experimental Dermatology, 18(11), 921-933. DOI:10.1111/j.1600-0625.2009.00942.x
    . Publication link: 87c0e302-3d51-4535-8e93-6ec16509afc7 | PubMed:19719838
  • Lin, K. K., Kumar, V., Geyfman, M., Chudova, D., Ihler, A. T., Smyth, P., ... Andersen, B. (2009). Circadian clock genes contribute to the regulation of hair follicle cycling. PLoS Genetics, 5(7), [e1000573]. DOI:10.1371/journal.pgen.1000573
    . Publication link: 61dd15be-1499-4ec0-81e9-2b65f8d23b2c | PubMed:19629164
  • Lu, Z., Fischer, T. W., Hasse, S., Sugawara, K., Kamenisch, Y., Krengel, S., ... Paus, R. (2009). Profiling the response of human hair follicles to ultraviolet radiation. Journal of Investigative Dermatology, 129(7), 1790-1804. DOI:10.1038/jid.2008.418
    . Publication link: 7c2607b6-4db1-4cf3-9bf2-59b8eda5df69
  • Meyer, K. C., Brzoska, T., Abels, C., & Paus, R. (2009). The α-melanocyte stimulating hormone-related tripeptide K(D)PT stimulates human hair follicle pigmentation in situ under proinflammatory conditions. British Journal of Dermatology, 160(2), 433-437. DOI:10.1111/j.1365-2133.2008.08872.x
    . Publication link: 4590be72-c80f-4b6c-849b-531a8ee3e52f
  • Paus, R., & Arck, P. (2009). Neuroendocrine perspectives in alopecia areata: Does stress play a role. Journal of Investigative Dermatology, 129(6), 1324-1326. DOI:10.1038/jid.2009.111
    . Publication link: f22473f1-594b-490d-bae3-e6ac76a22106 | PubMed:19434088
  • Paus, R., Bodó, E., Kromminga, A., & Jelkmann, W. (2009). Erythropoietin and the skin: A role for epidermal oxygen sensing?. BioEssays, 31(3), 344-348. DOI:10.1002/bies.200800192
    . Publication link: aafbdd13-582c-4fd9-bde6-0503f425b96f
  • Plonka, P. M., Passeron, T., Brenner, M., Tobin, D. J., Shibahara, S., Thomas, A., ... Schallreuter, K. U. (2009). What are melanocytes really doing all day long...?. Experimental Dermatology, 18(9), 799-819. DOI:10.1111/j.1600-0625.2009.00912.x
    . Publication link: 0b270b08-2cb4-4067-8f50-38416c4bf85b | PubMed:19659579
  • Ramot, Y., Gáspár, E., Dendorfer, A., Langbein, L., & Paus, R. (2009). The 'melanocyte-keratin' mystery revisited: Neither normal human epidermal nor hair follicle melanocytes express keratin 16 or keratin 6 in situ. British Journal of Dermatology, 161(4), 933-938. DOI:10.1111/j.1365-2133.2009.09294.x
    . Publication link: 5a23a9fd-643b-4dba-af63-b36d1a98588f
  • Ramot, Y., Paus, R., Tiede, S., & Zlotogorski, A. (2009). Endocrine controls of keratin expression. BioEssays, 31(4), 389-399. DOI:10.1002/bies.200800121
    . Publication link: 8d2d470e-48b1-4360-b701-6bce07b11412 | PubMed:19274655
  • Reithmayer, K., Meyer, K. C., Kleditzsch, P., Tiede, S., Uppalapati, S. K., Gläser, R., ... Paus, R. (2009). Human hair follicle epithelium has an antimicrobial defence system that includes the inducible antimicrobial peptide psoriasin (S100A7) and RNase 7. British Journal of Dermatology, 161(1), 78-89. DOI:10.1111/j.1365-2133.2009.09154.x
    . Publication link: be5ad7a2-1464-4647-9ed4-eb00f51a1ec9 | PubMed:19416233
  • Rückert, R., Brandt, K., Ernst, M., Marienfeld, K., Csernok, E., Metzler, C., ... Bulfone-Paus, S. (2009). Interleukin-15 stimulates macrophages to activate CD4+ T cells: A role in the pathogenesis of rheumatoid arthritis?. Immunology, 126(1), 63-73. DOI:10.1111/j.1365-2567.2008.02878.x
    . Publication link: 03d5112e-0567-427b-b714-42ad5f87043d | PubMed:18557790
  • Schneider, M. R., Schmidt-Ullrich, R., & Paus, R. (2009). The Hair Follicle as a Dynamic Miniorgan. Current Biology, 19(3), R132-R142. DOI:10.1016/j.cub.2008.12.005
    . Publication link: 5b00ce79-4949-42b9-9d37-ee86807bd8fd
  • Stelekati, E., Bahri, R., D'Orlando, O., Orinska, Z., Mittrücker, H. W., Langenhaun, R., ... Bulfone-Paus, S. (2009). Mast Cell-Mediated Antigen Presentation Regulates CD8+ T Cell Effector Functions. Immunity, 31(4), 665-676. DOI:10.1016/j.immuni.2009.08.022
    . Publication link: 62d978c5-d5a0-4f99-aa44-173f1db3d7f2 | PubMed:19818652
  • Tiede, S., Ernst, N., Bayat, A., Paus, R., Tronnier, V., & Zechel, C. (2009). Basic fibroblast growth factor: A potential new therapeutic tool for the treatment of hypertrophic and keloid scars. Annals of Anatomy, 191(1), 33-44. DOI:10.1016/j.aanat.2008.10.001
    . Publication link: 40f5ae20-ba30-4a85-8f1a-b1962c493f16 | PubMed:19071002
  • Tiede, S., Kloepper, J. E., Ernst, N., Poeggeler, B., Kruse, C., & Paus, R. (2009). Nestin in human skin: Exclusive expression in intramesenchymal skin compartments and regulation by leptin. Journal of Investigative Dermatology, 129(11), 2711-2720. DOI:10.1038/jid.2009.148
    . Publication link: 9ec40c90-c4e7-4061-8d5c-db16fea8102e
  • Tiede, S., Koop, N., Kloepper, J. E., Fässler, R., & Paus, R. (2009). Nonviral in situ green fluorescent protein labeling and culture of primary, adult human hair follicle epithelial progenitor cells. Stem Cells, 27(11), 2793-2803. DOI:10.1002/stem.213
    . Publication link: 0e0e1e06-d0a3-4613-8c8d-2b3ce228b7a4 | PubMed:19750535
  • Tóth, B. I., Géczy, T., Griger, Z., Dózsa, A., Seltmann, H., Kovács, L., ... Bíró, T. (2009). Transient receptor potential vanilloid-1 signaling as a regulator of human sebocyte biology. Journal of Investigative Dermatology, 129(2), 329-339. DOI:10.1038/jid.2008.258
    . Publication link: ca076044-fb2c-4c14-91b5-8a42765156a6
  • Wood, J. M., Decker, H., Hartmann, H., Chavan, B., Rokos, H., Spencer, J. D., ... Schallreuter, K. U. (2009). Senile hair graying: H2O2-mediated oxidative stress affects human hair color by blunting methionine sulfoxide repair. FASEB Journal, 23(7), 2065-2075. DOI:10.1096/fj.08-125435
    . Publication link: a1641d71-386c-482f-9efa-dc5d32529f2e
  • Wu, Z., Meyer-Hoffert, U., Reithmayer, K., Paus, R., Hansmann, B., He, Y., ... Schröder, J. M. (2009). Highly complex peptide aggregates of the S100 fused-type protein hornerin are present in human skin. Journal of Investigative Dermatology, 129(6), 1446-1458. DOI:10.1038/jid.2008.370
    . Publication link: 801f1016-22fb-45ea-8596-6d99bc92e220
  • Zhang, Y., Tomann, P., Andl, T., Gallant, N. M., Huelsken, J., Jerchow, B., ... Schmidt-Ullrich, R. (2009). Reciprocal Requirements for EDA/EDAR/NF-κB and Wnt/β-Catenin Signaling Pathways in Hair Follicle Induction. Developmental Cell, 17(1), 49-61. DOI:10.1016/j.devcel.2009.05.011
    . Publication link: 13bf7564-8cd7-4329-a6df-4e5872aeec2e | PubMed:19619491

2008

  • Adly, M. A., Assaf, H. A., Pertile, P., Hussein, M. R., & Paus, R. (2008). Expression patterns of the glial cell line-derived neurotrophic factor, neurturin, their cognate receptors GFRα-1, GFRα-2, and a common signal transduction element c-Ret in the human skin hair follicles. Journal of the American Academy of Dermatology, 58(2), 238-250. DOI:10.1016/j.jaad.2007.10.014
    . Publication link: 260566b7-6cdf-47ad-86ee-1fb87e6e38d5
  • Arck, P. C., Gilhar, A., Bienenstock, J., & Paus, R. (2008). The alchemy of immune privilege explored from a neuroimmunological perspective. Current Opinion in Pharmacology, 8(4), 480-489. DOI:10.1016/j.coph.2008.06.003
    . Publication link: fc3132c1-f53b-43b8-b853-cf22c8125471
  • Bulfone-Paus, S., & Paus, R. (2008). Osteopontin as a new player in mast cell biology. European Journal of Immunology, 38(2), 338-341. DOI:10.1002/eji.200738131
    . Publication link: 9d573b5b-2d87-4d60-af58-45291984bc03 | PubMed:18228246
  • Dobrosi, N., Tóth, B. I., Nagy, G., Dózsa, A., Géczy, T., Nagy, L., ... Bíró, T. (2008). Endocannabinoids enhance lipid synthesis and apoptosis of human sebocytes via cannabinoid receptor-2-mediated signaling. FASEB Journal, 22(10), 3685-3695. DOI:10.1096/fj.07-104877
    . Publication link: 8b336b18-c8b4-4b37-b1cc-3c57929cb249
  • Duitman, E. H., Orinska, Z., Bulanova, E., Paus, R., & Bulfone-Paus, S. (2008). How a cytokine is chaperoned through the secretory pathway by complexing with its own receptor: Lessons from interleukin-15 (IL-15)/IL-15 receptor. Molecular and Cellular Biology, 28(15), 4851-4861. DOI:10.1128/MCB.02178-07
    . Publication link: 7030627d-2efe-4c89-b3c5-d4e7996422e6 | PubMed:18505820
  • Fischer, T. W., Slominski, A., Tobin, D. J., & Paus, R. (2008). Melatonin and the hair follicle. Journal of Pineal Research, 44(1), 1-15. DOI:10.1111/j.1600-079X.2007.00512.x
    . Publication link: 8b5881e7-efe6-497b-b783-19c9ecbbf680 | PubMed:18078443
  • Fischer, T. W., Slominski, A., Zmijewski, M. A., Reiter, R. J., & Paus, R. (2008). Melatonin as a major skin protectant: From free radical scavenging to DNA damage repair. Experimental Dermatology, 17(9), 713-730. DOI:10.1111/j.1600-0625.2008.00767.x
    . Publication link: fe2b2083-072d-469a-b3a8-9b12042d0d33
  • Hadshiew, I., Barre, K., Bódó, E., Funk, W., & Paus, R. (2008). T-oligos as differential modulators of human scalp hair growth and pigmentation: A new "time lapse system" for studying human skin and hair follicle biology in vitro?. Archives of Dermatological Research, 300(4), 155-159. DOI:10.1007/s00403-008-0833-6
    . Publication link: 5f049df7-8847-4ae6-b823-2b2c7bfe410a
  • Harries, M. J., Sinclair, R. D., MacDonald-Hull, S., Whiting, D. A., Griffiths, C. E. M., & Paus, R. (2008). Management of primary cicatricial alopecias: Options for treatment. British Journal of Dermatology, 159(1), 1-22. DOI:10.1111/j.1365-2133.2008.08591.x
    . Publication link: c1c3d8e2-92fb-49e7-9c9a-8d5cded12139
  • Ito, T., Ito, N., Saatoff, M., Hashizume, H., Fukamizu, H., Nickoloff, B. J., ... Paus, R. (2008). Maintenance of hair follicle immune privilege is linked to prevention of NK cell attack. Journal of Investigative Dermatology, 128(5), 1196-1206. DOI:10.1038/sj.jid.5701183
    . Publication link: d12427ee-b90e-4dd7-9798-f2c5c8d8fe6b | PubMed:18160967
  • Ito, T., Meyer, K., Ito, N., & Paus, R. (2008). Immune privilege and the skin. Current directions in autoimmunity, 10, 27-52. DOI:10.1159/000131412
    . Publication link: f3231f87-d3b7-4eeb-996d-651847ea42c3
  • Joachim, R. A., Handjiski, B., Blois, S. M., Hagen, E., Paus, R., & Arck, P. C. (2008). Stress-induced neurogenic inflammation in murine skin skews dendritic cells towards maturation and migration: Key role of intercellular adhesion molecule-1/leukocyte function-associated antigen interactions. American Journal of Pathology, 173(5), 1379-1388. DOI:10.2353/ajpath.2008.080105
    . Publication link: 1f63e322-ba58-40a3-9a38-b0ab507bf407
  • Kajahn, J., Gorjup, E., Tiede, S., von Briesen, H., Paus, R., Kruse, C., & Danner, S. (2008). Skin-derived human adult stem cells surprisingly share many features with human pancreatic stem cells. European Journal of Cell Biology, 87(1), 39-46. DOI:10.1016/j.ejcb.2007.07.004
    . Publication link: 01c01f93-6375-4fff-98ed-b98424b09d1e
  • Kloepper, J. E., Hendrix, S., Bodó, E., Tiede, S., Humphries, M. J., Philpott, M. P., ... Paus, R. (2008). Functional role of β1 integrin-mediated signalling in the human hair follicle. Experimental Cell Research, 314(3), 498-508. DOI:10.1016/j.yexcr.2007.10.030
    . Publication link: 3f76eb33-38d4-4987-9dff-9871e6e14c51 | PubMed:18155697
  • Kloepper, J. E., Tiede, S., Brinckmann, J., Reinhardt, D. P., Meyer, W., Faessler, R., & Paus, R. (2008). Immunophenotyping of the human bulge region: The quest to define useful in situ markers for human epithelial hair follicle stem cells and their niche. Experimental Dermatology, 17(7), 592-609. DOI:10.1111/j.1600-0625.2008.00720.x
    . Publication link: 1dd5c648-8f54-438f-a8d5-ff46028657f0
  • Meyer, K. C., Klatte, J. E., Dinh, H. V., Harries, M. J., Reithmayer, K., Meyer, W., ... Paus, R. (2008). Evidence that the bulge region is a site of relative immune privilege in human hair follicles. British Journal of Dermatology, 159(5), 1077-1085. DOI:10.1111/j.1365-2133.2008.08818.x
    . Publication link: 2b9c6322-3d75-41b4-992f-abea91119602
  • Paus, R., Arck, P., & Tiede, S. (2008). (Neuro-)endocrinology of epithelial hair follicle stem cells. Molecular and Cellular Endocrinology, 288(1-2), 38-51. DOI:10.1016/j.mce.2008.02.023
    . Publication link: f305c327-edd0-4376-9d69-9c2c78bce763
  • Plonka, P. M., Michalczyk, D., Popik, M., Handjiski, B., & Paus, R. (2008). Electron paramagnetic resonance (EPR) spectroscopy for investigating murine telogen skin after spontaneous or depilation-induced hair growth. Journal of Dermatological Science, 49(3), 227-240. DOI:10.1016/j.jdermsci.2007.09.010
    . Publication link: 63e3a26e-c3f6-458c-a3f0-8555abddcb11 | PubMed:18061408
  • Schallreuter, K. U., Bahadoran, P., Picardo, M., Slominski, A., Elassiuty, Y. E., Kemp, E. H., ... Westerof, W. (2008). Vitiligo pathogenesis: Autoimmune disease, genetic defect, excessive reactive oxygen species, calcium imbalance, or what else?. Experimental Dermatology, 17(2), 139-140. DOI:10.1111/j.1600-0625.2007.00666_1.x
    . Publication link: 64342bf2-2ae4-4e1e-b89e-8e95236e4651
  • Schneider, M. R., Antsiferova, M., Feldmeyer, L., Dahlhoff, M., Bugnon, P., Hasse, S., ... Werner, S. (2008). Betacellulin regulates hair follicle development and hair cycle induction and enhances angiogenesis in wounded skin. Journal of Investigative Dermatology, 128(5), 1256-1265. DOI:10.1038/sj.jid.5701135
    . Publication link: 48b9a8fe-845e-4560-af65-c4a9424cb35f
  • Schneider, M. R., Werner, S., Paus, R., & Wolf, E. (2008). Beyond wavy hairs: The epidermal growth factor receptor and its ligands in skin biology and pathology. American Journal of Pathology, 173(1), 14-24. DOI:10.2353/ajpath.2008.070942
    . Publication link: 7234a036-aa46-4f52-83a9-39693937acd3
  • Semenova, E., Koegel, H., Hasse, S., Klatte, J. E., Slonimsky, E., Bilbao, D., ... Rosenthal, N. (2008). Overexpression of mIGF-1 in keratinocytes improves wound healing and accelerates hair follicle formation and cycling in mice. American Journal of Pathology, 173(5), 1295-1310. DOI:10.2353/ajpath.2008.071177
    . Publication link: b9bf741a-6edb-4c87-b8ce-fd4ba36fb5ec
  • Slominski, A., Tobin, D. J., Zmijewski, M. A., Wortsman, J., & Paus, R. (2008). Melatonin in the skin: synthesis, metabolism and functions.Trends in Endocrinology and Metabolism, 19(1), 17-24. DOI:10.1016/j.tem.2007.10.007
    . Publication link: bce9e6b9-e255-44bd-a69d-01ed5a34154f | PubMed:18155917
  • Slominski, A., Wortsman, J., Paus, R., Elias, P. M., Tobin, D. J., & Feingold, K. R. (2008). Skin as an endocrine organ: implications for its function. Drug Discovery Today: Disease Mechanisms, 5(2), e137-e144. DOI:10.1016/j.ddmec.2008.04.004
    . Publication link: 0d22b42f-8484-40d3-9f95-4f7ce559fcc0 | PubMed:19492070
  • Van Beek, N., Bodó, E., Kromminga, A., Gáspár, E., Meyer, K., Zmijewski, M. A., ... Paus, R. (2008). Thyroid hormones directly alter human hair follicle functions: Anagen prolongation and stimulation of both hair matrix keratinocyte proliferation and hair pigmentation. Journal of Clinical Endocrinology and Metabolism, 93(11), 4381-4388. DOI:10.1210/jc.2008-0283
    . Publication link: e4e6db5f-5686-4e5c-b9a0-5811ba85551e

2007

2006

  • Adly, M. A., Assaf, H. A., Hussein, M. R., & Paus, R. (2006). Analysis of the expression pattern of glial cell line-derived neurotrophic factor, neurturin, their cognate receptors GFRα-1 and GFRα-2, and a common signal transduction element c-Ret in the human scalp skin. Journal of cutaneous pathology, 33(12), 799-808. DOI:10.1111/j.1600-0560.2006.00561.x
    . Publication link: aaab5f73-d6f7-4b22-a982-947dffca5062 | PubMed:17177940
  • Botchkarev, V. A., Yaar, M., Peters, E. M. J., Raychaudhuri, S. P., Botchkareva, N. V., Marconi, A., ... Pincelli, C. (2006). Neurotrophins in skin biology and pathology. Journal of Investigative Dermatology, 126(8), 1719-1727. DOI:10.1038/sj.jid.5700270
    . Publication link: 3aafaade-f9d4-4b53-9a2e-0eeb284df659 | PubMed:16845411
  • Braun, S., Krampert, M., Bodó, E., Kümin, A., Born-Berclaz, C., Paus, R., & Werner, S. (2006). Keratinocyte growth factor protects epedermis and hair follicles from cell death induced by UV irradiation, chemotherapeutic or cytotoxic agents. Journal of Cell Science, 119(23), 4841-4849. DOI:10.1242/jcs.03259
    . Publication link: b590fe81-bd4a-4300-ba70-5dfe0687b4c1 | PubMed:17090603
  • Budagian, V., Bulanova, E., Paus, R., & Bulfone-Paus, S. (2006). IL-15/IL-15 receptor biology: A guided tour through an expanding universe. Cytokine and Growth Factor Reviews, 17(4), 259-280. DOI:10.1016/j.cytogfr.2006.05.001
    . Publication link: f325a8da-2892-4c78-afbd-43da8ca041dd | PubMed:16815076
  • Foitzik, K., Krause, K., Conrad, F., Nakamura, M., Funk, W., & Paus, R. (2006). Human scalp hair follicles are both a target and a source of prolactin, which serves as an autocrine and/or paracrine promoter of apoptosis-driven hair follicle regression. American Journal of Pathology, 168(3), 748-756. DOI:10.2353/ajpath.2006.050468
    . Publication link: 40e8600e-6000-48d2-9306-1958f77425bb | PubMed:16507890
  • Hiroi, A., Ito, T., Seo, N., Uede, K., Yoshimasu, T., Ito, M., ... Furukawa, F. (2006). Male New Zealand Black/KN mice: A novel model for autoimmune-induced permanent alopecia?. British Journal of Dermatology, 155(2), 437-445. DOI:10.1111/j.1365-2133.2006.07204.x
    . Publication link: 3750bbf6-fe23-42d2-9fc7-794a0e653c26 | PubMed:16882186
  • Kruse, C., Bodó, E., Petschnik, A. E., Danner, S., Tiede, S., & Paus, R. (2006). Towards the development of a pragmatic technique for isolating and differentiating nestin-positive cells from human scalp skin into neuronal and glial cell populations: Generating neurons from human skin?. Experimental Dermatology, 15(10), 794-800. DOI:10.1111/j.1600-0625.2006.00471.x
    . Publication link: 7503d479-77b6-42b5-8284-518e7917ea1a | PubMed:16984261
  • Ohnemus, U., Uenalan, M., Inzunza, J., Gustafsson, J. Å., & Paus, R. (2006). The hair follicle as an estrogen target and source. Endocrine Reviews, 27(6), 677-706. DOI:10.1210/er.2006-0020
    . Publication link: 95911e95-e025-414c-ac2a-be02143f43e6 | PubMed:16877675
  • Paus, R., Schmelz, M., Bíró, T., & Steinhoff, M. (2006). Frontiers in pruritus research: Scratching the brain for more effective itch therapy. Journal of Clinical Investigation, 116(5), 1174-1185. DOI:10.1172/JCI28553
    . Publication link: 1a432978-2cad-4579-af55-66da284fa1b8 | PubMed:16670758
  • Peters, E. M. J., Ericson, M. E., Hosoi, J., Seiffert, K., Hordinsky, M. K., Ansel, J. C., ... Scholzen, T. E. (2006). Neuropeptide control mechanisms in cutaneous biology: Physiological and clinical significance. Journal of Investigative Dermatology, 126(9), 1937-1947. DOI:10.1038/sj.jid.5700429
    . Publication link: f259ceab-07e6-4363-bfb8-d197fca66e60 | PubMed:16912691
  • Peters, E. M. J., Stieglitz, M. G., Liezman, C., Overall, R. W., Nakamura, M., Hagen, E., ... Paus, R. (2006). p75 neurotrophin receptor-mediated signaling promotes human hair follicle regression (catagen). American Journal of Pathology, 168(1), 221-234. DOI:10.2353/ajpath.2006.050163
    . Publication link: 33742c5c-f403-4bd9-b56a-bb75cedbd219 | PubMed:16400025
  • Plonka, P. M., Handjiski, B., Michalczyk, D., Popik, M., & Paus, R. (2006). Oral zinc sulphate causes murine hair hypopigmentation and is a potent inhibitor of eumelanogenesis in vivo. British Journal of Dermatology, 155(1), 39-49. DOI:10.1111/j.1365-2133.2006.07376.x
    . Publication link: 8caac287-25e9-4dce-8551-b48e9b7441fd | PubMed:16792750
  • Schmidt-Ullrich, R., Tobin, D. J., Lenhard, D., Schneider, P., Paus, R., & Scheidereit, C. (2006). NF-κB transmits Eda A1/EdaR signalling to activate Shh and cyclin D1 expression, and controls post-initiation hair placode down growth. Development, 133(6), 1045-1057. DOI:10.1242/dev.02278
    . Publication link: 5189192a-80a1-4fdd-8ed2-5df36335d3be | PubMed:16481354
  • Tiede, S., & Paus, R. (2006). Lhx2 - Decisive role in epithelial stem cell maintenance, or just the "tip of the iceberg"?. BioEssays, 28(12), 1157-1160. DOI:10.1002/bies.20506
    . Publication link: 1f7868cc-1a17-4b6b-88a5-0eacbe55e024 | PubMed:17117482
  • Weller, K., Foitzik, K., Paus, R., Syska, W., & Maurer, M. (2006). Mast cells are required for normal healing of skin wounds in mice.The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 20(13). DOI:10.1096/fj.06-5837fje
    . Publication link: 4713eb51-bb0c-48cb-9585-45cf677fdc3d | PubMed:16966487
  • Widelitz, R. B., Baker, R. E., Plikus, M., Lin, C. M., Maini, P. K., Paus, R., & Chuong, C. M. (2006). Distinct mechanisms underlie pattern formation in the skin and skin appendages. Birth Defects Research Part C - Embryo Today: Reviews, 78(3), 280-291. DOI:10.1002/bdrc.20075
    . Publication link: 6cb1fd1a-b4a6-4861-9a7b-f607ea5183b6 | PubMed:17061271
  • Wu, X., Quondamatteo, F., Lefever, T., Czuchra, A., Meyer, H., Chrostek, A., ... Brakebusch, C. (2006). Cdc42 controls progenitor cell differentiation and β-catenin turnover in skin. Genes and Development, 20(5), 571-585. DOI:10.1101/gad.361406
    . Publication link: bdf5ad93-5d23-4e44-9310-bdf586ea045d | PubMed:16510873