Professor Ralf Paus

Photograph of Ralf Paus

Professor of Cutaneous Medicine, University of Manchester and Professor of Dermatology and Experimental Dermatology, University of Luebeck


  Professor of Cutaneous Medicine
  Dermatological Sciences Research Group
  School of Translational Medicine
  University of Manchester
  Stopford Building
  Oxford Road
  Manchester M13 9PL
 

Role

Professor Ralf Paus researches into hair disorders, skin neuroendocrinology,  and the science and applications of stem cells residing in the skin.

Research

Ralf researches into the biology and pathology of the hair follicle as a microcosmic miniorgan in which many of the fundamental problems of biology can be studied exemplarily. Currently, he is most intrigued by the astounding neuroendocrine properties of the human hair follicle, their impact on mitochondrial function and hair follicle immune status, and the use ofadult stem cells populations associated with human skin appendages for regenerative medicine pursposes. 

Ralf's particular interest is in:

  • better defining and in manipulating various neuroendocrine pathways established in the human hair follicle (HPA and HPT axis equivalent systems) and in elucidating novel functions of this neuroendocrine activity
  • neuroendocrine controls of mitochondrial activity and biogenesis in human skin
  • understanding the controls and functions of hair follicle immune privilege and its disorders that lead to alopecia areata or scarring alopecia
  • characterizing, selectively labelling, isolating and differentiating various stem cells populations associated with human scalp skin and its appendages
  • role of clock genes in human growth control

Methodologically, Ralf employs mainly human hair follicle and scalp skin organ culture, K15-GFP+ human epithelial hair follicle stem cells, and immunohistology/immunofluorescence, and analyzes the hair and skin phenotype of relevant mouse mutants.

Biography

After his medical studies at the Unversities of Wuerzburg, Berlin and Vienna, MD thesis work at the University of South Florida, Tampa, USA, and an internship at the University Hospitals of Basle and Zurich, Switzerland, Ralf graduated from the Free University of Berlin (1987).

Following post-doctoral research at Yale University (1987-90), Ralf trained as a clinical dermatologist in Berlin, where he became consultant dermatologist and junior faculty at the Charité University Hospital. From 1999-2004 Ralf served as Professor and Vice-Chair of the Dept. of Dermatology, University Hospital Hamburg-Eppendorf, University of Hamburg. He was Visiting Scholar at the University of California, San Diego (1992), Visiting Professor at the Dept. of Molecular Medicine at the Max-Planck-Institute for Biochemistry, Munich-Martinsried (2005), and Honorary Visiting Professor at the University of Bradford until 2010 and again since 2012.


After taking up  his current position as Head of Experimental Dermatology, Dept. of Dermatology, University of Luebeck, Germany (2005), Ralf  joined the University of Manchester in 2008 as Professor of Cutaneous Medicine).

Ralf has been Editor of Experimental Dermatology since 2007.
 

Collaborators and affiliated staff

Professor Enrique Amaya - The Healing Foundation, University of Manchester

Publications

2014

  • Yusur Al-Nuaimi, Jonathan A Hardman, Tamás Bíró, Iain S Haslam, Michael P Philpott, Balázs.I.Tóth, Nilofer Farjo, Bessam Farjo, Gerold Baier, Rachel E B Watson, Benedetto Grimaldi, Jennifer E Kloepper and Ralf Paus. (2014). A Meeting of Two Chronobiological Systems: Circadian Proteins Period1 and BMAL1 Modulate the Human Hair Cycle Clock. J I D, 134(3), 610-619. eScholarID:222342 | DOI:10.1038/jid.2013.366

2013

  • Kloepper, J., Kawai, K., Bertolini, M., Kanekura, T. & Paus, R (2013). Loss of γδ T Cells Results in Hair Cycling Defects. J Invest Dermatol, eScholarID:190925 | PMID:23334345 | DOI:10.1038/jid.2013.17
  • Langan, E., Lisztes, E., Bíró, T., Funk, W., Kloepper, J., Griffiths, C. & Paus, R (2013). Dopamine is a novel, direct inducer of catagen in human scalp hair follicles in vitro. Br J Dermatol, 168(3), 520-5. eScholarID:190931 | PMID:23176199 | DOI:10.1111/bjd.12113
  • Nakamura, M., Schneider, M., Schmidt-Ullrich, R. & Paus, R (2013). Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and/or structure: an update. J Dermatol Sci, 69(1), 6-29. eScholarID:190932 | PMID:23165165 | DOI:10.1016/j.jdermsci.2012.10.001
  • Paus, R., Haslam, I., Sharov, A. & Botchkarev, V (2013). Pathobiology of chemotherapy-induced hair loss. Lancet Oncol, 14(2), e50-9. eScholarID:190926 | PMID:23369683 | DOI:10.1016/S1470-2045(12)70553-3
  • Rakers, S., Niklasson, L., Steinhagen, D., Kruse, C., Schauber, J., Sundell, K. & Paus, R (2013). Antimicrobial Peptides (AMPs) from Fish Epidermis: Perspectives for Investigative Dermatology. J Invest Dermatol, eScholarID:190930 | PMID:23407389 | DOI:10.1038/jid.2012.503
  • Ramot, Y., Zhang, G., Bíró, T., Langbein, L. & Paus, R (2013). Is thyrotropin-releasing hormone (TRH) a novel neuroendocrine modulator of keratin expression in human skin? Br J Dermatol, eScholarID:190928 | PMID:23373458 | DOI:10.1111/bjd.12264
  • Samuelov, L., Sprecher, E., Sugawara, K., Singh, S., Tobin, D., Tsuruta, D., Bíró, T., Kloepper, J. & Paus, R (2013). Topobiology of Human Pigmentation: P-Cadherin Selectively Stimulates Hair Follicle Melanogenesis. J Invest Dermatol, eScholarID:190927 | PMID:23334344 | DOI:10.1038/jid.2013.18
  • Sugawara, K., Zákány, N., Hundt, T., Emelianov, V., Tsuruta, D., Schäfer, C., Kloepper, J., Bíró, T. & Paus, R (2013). Cannabinoid receptor 1 controls human mucosal-type mast cell degranulation and maturation in situ. J Allergy Clin Immunol, 132(1), 182-193.e8. eScholarID:190929 | PMID:23453134 | DOI:10.1016/j.jaci.2013.01.002

2012

  • Al-Nuaimi, Y., Goodfellow, M., Paus, R. & Baier, G (2012). A prototypic mathematical model of the human hair cycle. J Theor Biol, 310, 143-59. eScholarID:169039 | PMID:22677396 | DOI:10.1016/j.jtbi.2012.05.027
  • Bagabir, R., Byers, R., Chaudhry, I., Müller, W., Paus, R. & Bayat, A (2012). Site-specific immunophenotyping of keloid disease demonstrates immune upregulation and the presence of lymphoid aggregates. Br J Dermatol, 167(5), 1053-66. eScholarID:190933 | PMID:23106354 | DOI:10.1111/j.1365-2133.2012.11190.x
  • Bagabir, R., Syed, F., Paus, R. & Bayat, A (2012). Long-term organ culture of keloid disease tissue. Exp Dermatol, 21(5), 376-81. eScholarID:161166 | PMID:22509836 | DOI:10.1111/j.1600-0625.2012.01476.x
  • Bagabir, R., Syed, F., Paus, R. & Bayat, A (2012). Long-term organ culture of keloid disease tissue. Exp Dermatol, 21(5), 376-81. eScholarID:169050 | PMID:22509836 | DOI:10.1111/j.1600-0625.2012.01476.x
  • Behrendt, K., Klatte, J., Pofahl, R., Bloch, W., Smyth, N., Tscharntke, M., Krieg, T., Paus, R., Niessen, C., Niemann, C., Brakebusch, C. & Haase, I (2012). A function for Rac1 in the terminal differentiation and pigmentation of hair. J Cell Sci, 125(Pt 4), 896-905. eScholarID:169036 | PMID:22275433 | DOI:10.1242/jcs.091868
  • Bertolini, M., Gilhar, A. & Paus, R (2012). Alopecia areata as a model for T cell-dependent autoimmune diseases. Exp Dermatol, 21(6), 477-9. eScholarID:169041 | PMID:22621196 | DOI:10.1111/j.1600-0625.2011.01427.x
  • Böhm, M., Apel, M., Sugawara, K., Brehler, R., Jurk, K., Luger, T., Haas, H., Paus, R., Eiz-Vesper, B., Walls, A., Ponimaskin, E., Gehring, M., Kapp, A. & Raap, U (2012). Modulation of basophil activity: a novel function of the neuropeptide α-melanocyte-stimulating hormone. J Allergy Clin Immunol, 129(4), 1085-93. eScholarID:161164 | PMID:22178636 | DOI:10.1016/j.jaci.2011.11.012
  • Böhm, M., Apel, M., Sugawara, K., Brehler, R., Jurk, K., Luger, T., Haas, H., Paus, R., Eiz-Vesper, B., Walls, A., Ponimaskin, E., Gehring, M., Kapp, A. & Raap, U (2012). Modulation of basophil activity: a novel function of the neuropeptide α-melanocyte-stimulating hormone. J Allergy Clin Immunol, 129(4), 1085-93. eScholarID:169049 | PMID:22178636 | DOI:10.1016/j.jaci.2011.11.012
  • Chiang, Y., Tosti, A., Chaudhry, I., Lyne, L., Farjo, B., Farjo, N., Cadore de Farias, D., Griffiths, C., Paus, R. & Harries, M (2012). Lichen planopilaris following hair transplantation and face-lift surgery. Br J Dermatol, 166(3), 666-370. eScholarID:161161 | PMID:21985326 | DOI:10.1111/j.1365-2133.2011.10692.x
  • Chiang, Y., Tosti, A., Chaudhry, I., Lyne, L., Farjo, B., Farjo, N., Cadore de Farias, D., Griffiths, C., Paus, R. & Harries, M (2012). Lichen planopilaris following hair transplantation and face-lift surgery. Br J Dermatol, 166(3), 666-370. eScholarID:169047 | PMID:21985326 | DOI:10.1111/j.1365-2133.2011.10692.x
  • Emelianov, V., Bechara, F., Gläser, R., Langan, E., Taungjaruwinai, W., Schröder, J., Meyer, K. & Paus, R (2012). Immunohistological pointers to a possible role for excessive cathelicidin (LL-37) expression by apocrine sweat glands in the pathogenesis of hidradenitis suppurativa/acne inversa. Br J Dermatol, 166(5), 1023-34. eScholarID:161168 | PMID:22136668 | DOI:10.1111/j.1365-2133.2011.10765.x
  • Emelianov, V., Bechara, F., Gläser, R., Langan, E., Taungjaruwinai, W., Schröder, J., Meyer, K. & Paus, R (2012). Immunohistological pointers to a possible role for excessive cathelicidin (LL-37) expression by apocrine sweat glands in the pathogenesis of hidradenitis suppurativa/acne inversa. Br J Dermatol, 166(5), 1023-34. eScholarID:169073 | PMID:22136668 | DOI:10.1111/j.1365-2133.2011.10765.x
  • Géczy, T., Oláh, A., Tóth, B., Czifra, G., Szöllősi, A., Szabó, T., Zouboulis, C., Paus, R. & Bíró, T (2012). Protein Kinase C Isoforms Have Differential Roles in the Regulation of Human Sebocyte Biology. J Invest Dermatol, eScholarID:161173 | PMID:22475757 | DOI:10.1038/jid.2012.94
  • Géczy, T., Oláh, A., Tóth, B., Czifra, G., Szöllősi, A., Szabó, T., Zouboulis, C., Paus, R. & Bíró, T (2012). Protein kinase C isoforms have differential roles in the regulation of human sebocyte biology. J Invest Dermatol, 132(8), 1988-97. eScholarID:169058 | PMID:22475757 | DOI:10.1038/jid.2012.94
  • Gilhar, A., Etzioni, A. & Paus, R (2012). Alopecia areata. N Engl J Med, 366(16), 1515-25. eScholarID:169044 | PMID:22512484 | DOI:10.1056/NEJMra1103442
  • Holub, B., Kloepper, J., Tóth, B., Bíro, T., Kofler, B. & Paus, R (2012). The neuropeptide galanin is a novel inhibitor of human hair growth. Br J Dermatol, 167(1), 10-6. eScholarID:169060 | PMID:22329353 | DOI:10.1111/j.1365-2133.2012.10890.x
  • Knuever, J., Poeggeler, B., Gáspár, E., Klinger, M., Hellwig-Burgel, T., Hardenbicker, C., Tóth, B., Bíró, T. & Paus, R (2012). Thyrotropin-releasing hormone controls mitochondrial biology in human epidermis. J Clin Endocrinol Metab, 97(3), 978-86. eScholarID:169067 | PMID:22259067 | DOI:10.1210/jc.2011-1096
  • Knuever, J., Poeggeler, B., Gáspár, E., Klinger, M., Hellwig-Burgel, T., Hardenbicker, C., Tóth, B., Bíró, T. & Paus, R (2012). Thyrotropin-releasing hormone controls mitochondrial biology in human epidermis. J Clin Endocrinol Metab, 97(3), 978-86. eScholarID:169115 | PMID:22259067 | DOI:10.1210/jc.2011-1096
  • Langan, E., Griffiths, C. & Paus, R (2012). Exploring the role of prolactin in psoriasis. Arch Dermatol Res, 304(2), 115-8. eScholarID:161156 | PMID:22249743 | DOI:10.1007/s00403-012-1208-6
  • Langan, E., Griffiths, C. & Paus, R (2012). Exploring the role of prolactin in psoriasis. Arch Dermatol Res, 304(2), 115-8. eScholarID:169071 | PMID:22249743 | DOI:10.1007/s00403-012-1208-6
  • Luger, T. & Paus, R (2012). Expression of concern. Exp Dermatol, 21(3), 240. eScholarID:161172 | PMID:22379976 | DOI:10.1111/j.1600-0625.2012.01444.x
  • Luger, T. & Paus, R (2012). Expression of concern. Exp Dermatol, 21(3), 240. eScholarID:169072 | PMID:22379976 | DOI:10.1111/j.1600-0625.2012.01444.x
  • Mul, D., Wu, S., de Paus, R., Oostdijk, W., Lankester, A., Duyvenvoorde, H., Ruivenkamp, C., Losekoot, M., Tol, M., De Luca, F., van de Vosse, E. & Wit, J (2012). A mosaic de novo duplication of 17q21-25 is associated with GH insensitivity, disturbed in vitro CD28-mediated signaling, and decreased STAT5B, PI3K, and NF-κB activation. Eur J Endocrinol, 166(4), 743-52. eScholarID:169040 | PMID:22214923 | DOI:10.1530/EJE-11-0774
  • Potjewijd, J., de Paus, R., van Wengen, A., Damoiseaux, J., Verbon, A. & de Vosse, E (2012). Disseminated Mycobacterium genavense infection in a patient with a novel partial interleukin-12/23 receptor β1 deficiency. Clin Immunol, 144(2), 83-6. eScholarID:169056 | PMID:22695533 | DOI:10.1016/j.clim.2012.05.007
  • Samuelov, L., Sprecher, E., Tsuruta, D., Bíró, T., Kloepper, J. & Paus, R (2012). P-Cadherin Regulates Human Hair Growth and Cycling via Canonical Wnt Signaling and Transforming Growth Factor-β2. J Invest Dermatol, eScholarID:169048 | PMID:22696062 | DOI:10.1038/jid.2012.171
  • Samuelov, L., Sprecher, E., Tsuruta, D., Bíró, T., Kloepper, J. & Paus, R (2012). P-cadherin regulates human hair growth and cycling via canonical Wnt signaling and transforming growth factor-β2. J Invest Dermatol, 132(10), 2332-41. eScholarID:190935 | PMID:22696062 | DOI:10.1038/jid.2012.171
  • Sugawara, K., Bíró, T., Tsuruta, D., Tóth, B., Kromminga, A., Zákány, N., Zimmer, A., Funk, W., Gibbs, B., Zimmer, A. & Paus, R (2012). Endocannabinoids limit excessive mast cell maturation and activation in human skin. J Allergy Clin Immunol, 129(3), 726-738.e8. eScholarID:169053 | PMID:22226549 | DOI:10.1016/j.jaci.2011.11.009
  • Sugawara, K., Bíró, T., Tsuruta, D., Tóth, B., Kromminga, A., Zákány, N., Zimmer, A., Funk, W., Gibbs, B., Zimmer, A. & Paus, R (2012). Endocannabinoids limit excessive mast cell maturation and activation in human skin. The Journal of allergy and clinical immunology, 129(3), 726. eScholarID:161154 | PMID:22226549 | DOI:10.1016/j.jaci.2011.11.009
  • Syed, F., Sherris, D., Paus, R., Varmeh, S., Pandolfi, P. & Bayat, A (2012). Keloid disease can be inhibited by antagonizing excessive mTOR signaling with a novel dual TORC1/2 inhibitor. Am J Pathol, 181(5), 1642-58. eScholarID:190934 | PMID:22982188 | DOI:10.1016/j.ajpath.2012.08.006

2011

  • Al-Nuaimi, Y., Kloepper, J., Watson, R. & Paus, R (2011). Towards deciphering a gene signature of anagen vs catagen in human hair follicles. BRITISH JOURNAL OF DERMATOLOGY, 164(4), 930-930. eScholarID:126909
  • Al-Nuaimi, Y., Paus, R. & Baier, G (2011). Controlled switching between states of epithelial proliferation and apoptosis in a mathematical model of the human hair cycle. BRITISH JOURNAL OF DERMATOLOGY, 164(4), 915-915. eScholarID:126910
  • Ansell, D., Kloepper, J., Thomason, H., Paus, R. & Hardman, M (2011). Exploring the "hair growth-wound healing connection": anagen phase promotes wound re-epithelialization. J Invest Dermatol, 131(2), 518-28. eScholarID:161157 | PMID:20927125 | DOI:10.1038/jid.2010.291
  • Ansell, D., Kloepper, J., Thomason, H., Paus, R. & Hardman, M (2011). Exploring the "hair growth-wound healing connection": anagen phase promotes wound re-epithelialization. J Invest Dermatol, 131(2), 518-28. eScholarID:169069 | PMID:20927125 | DOI:10.1038/jid.2010.291
  • Ariza de Schellenberger, A., Horland, R., Rosowski, M., Paus, R., Lauster, R. & Lindner, G (2011). Cartilage oligomeric matrix protein (COMP) forms part of the connective tissue of normal human hair follicles. Exp Dermatol, 20(4), 361-6. eScholarID:161167 | PMID:21355885 | DOI:10.1111/j.1600-0625.2010.01217.x
  • Ariza de Schellenberger, A., Horland, R., Rosowski, M., Paus, R., Lauster, R. & Lindner, G (2011). Cartilage oligomeric matrix protein (COMP) forms part of the connective tissue of normal human hair follicles. Exp Dermatol, 20(4), 361-6. eScholarID:169042 | PMID:21355885 | DOI:10.1111/j.1600-0625.2010.01217.x
  • Bagabir, R., Syed, F., Paus, R. & Bayat, A (2011). A NOVEL LONG-TERM HUMAN ORGAN CULTURE MODEL IN KELOID DISEASE DEMONSTRATES IN-SITU FUNCTIONAL ANALYSIS AND EVALUATES POTENTIAL THERAPEUTIC COMPOUNDS. WOUND REPAIR AND REGENERATION, 19(2), A11-A11. eScholarID:126905
  • Bagabir, R., Syed, F., Rautemaa, R., McGrouther, D., Paus, R. & Bayat, A (2011). UP-REGULATION OF TOLL-LIKE RECEPTORS (TLR) 6, 7 AND 8 IN KELOID SCARS: DOES KELOID DISEASE REFLECT AN ABNORMAL INNATE IMMUNE RESPONSE TO VIRAL INFECTION? WOUND REPAIR AND REGENERATION, 19(2), A11-A11. eScholarID:126904
  • Baris, O., Klose, A., Kloepper, J., Weiland, D., Neuhaus, J., Schauen, M., Wille, A., Müller, A., Merkwirth, C., Langer, T., Larsson, N., Krieg, T., Tobin, D., Paus, R. & Wiesner, R (2011). The mitochondrial electron transport chain is dispensable for proliferation and differentiation of epidermal progenitor cells. Stem Cells, 29(9), 1459-68. eScholarID:145539 | PMID:21780252 | DOI:10.1002/stem.695
  • Baris, O., Klose, A., Kloepper, J., Weiland, D., Neuhaus, J., Schauen, M., Wille, A., Müller, A., Merkwirth, C., Langer, T., Larsson, N., Krieg, T., Tobin, D., Paus, R. & Wiesner, R (2011). The mitochondrial electron transport chain is dispensable for proliferation and differentiation of epidermal progenitor cells. Stem Cells, 29(9), 1459-68. eScholarID:169059 | PMID:21780252 | DOI:10.1002/stem.695
  • Böhm, M., Apel, M., Sugawara, K., Brehler, R., Jurk, K., Luger, T., Haas, H., Paus, R., Eiz-Vesper, B., Walls, A., Ponimaskin, E., Gehring, M., Kapp, A. & Raap, U (2011). Modulation of basophil activity: A novel function of the neuropeptide α-melanocyte-stimulating hormone. J Allergy Clin Immunol, eScholarID:145535 | PMID:22178636 | DOI:10.1016/j.jaci.2011.11.012
  • Borbíró, I., Lisztes, E., Tóth, B., Czifra, G., Oláh, A., Szöllosi, A., Szentandrássy, N., Nánási, P., Péter, Z., Paus, R., Kovács, L. & Bíró, T (2011). Activation of transient receptor potential vanilloid-3 inhibits human hair growth. J Invest Dermatol, 131(8), 1605-14. eScholarID:161149 | PMID:21593771 | DOI:10.1038/jid.2011.122
  • Borbíró, I., Lisztes, E., Tóth, B., Czifra, G., Oláh, A., Szöllosi, A., Szentandrássy, N., Nánási, P., Péter, Z., Paus, R., Kovács, L. & Bíró, T (2011). Activation of transient receptor potential vanilloid-3 inhibits human hair growth. J Invest Dermatol, 131(8), 1605-14. eScholarID:169045 | PMID:21593771 | DOI:10.1038/jid.2011.122
  • Chiang, Y., Tosti, A., Chaudhry, I., Lyne, L., Farjo, B., Farjo, N., Cadore de Farias, D., Griffiths, C., Paus, R. & Harries, M (2011). Lichen Planopilaris following Hair Transplantation and Face-lift Surgery. Br J Dermatol, eScholarID:145532 | PMID:21985326 | DOI:10.1111/j.1365-2133.2011.10692.x
  • Duheron, V., Amoasii, L., Decossas, M., Paus, R. & Mueller, C (2011). HAIR FOLLICLE RANK-LIGAND REGULATES EPITHELIAL GROWTH VIA BCL-3. ADVANCES IN TNF FAMILY RESEARCH, 691, 644-645. eScholarID:126912
  • Duheron, V., Hess, E., Duval, M., Decossas, M., Castaneda, B., Klöpper, J., Amoasii, L., Barbaroux, J., Williams, I., Yagita, H., Penninger, J., Choi, Y., Lézot, F., Groves, R., Paus, R. & Mueller, C (2011). Receptor activator of NF-kappaB (RANK) stimulates the proliferation of epithelial cells of the epidermo-pilosebaceous unit. Proc Natl Acad Sci U S A, 108(13), 5342-7. eScholarID:161165 | PMID:21402940 | DOI:10.1073/pnas.1013054108
  • Duheron, V., Hess, E., Duval, M., Decossas, M., Castaneda, B., Klöpper, J., Amoasii, L., Barbaroux, J., Williams, I., Yagita, H., Penninger, J., Choi, Y., Lézot, F., Groves, R., Paus, R. & Mueller, C (2011). Receptor activator of NF-κB (RANK) stimulates the proliferation of epithelial cells of the epidermo-pilosebaceous unit. Proc Natl Acad Sci U S A, 108(13), 5342-5347. eScholarID:169062 | PMID:21402940 | DOI:10.1073/pnas.1013054108
  • Ernst, N., Tiede, S., Humphries, M., Paus, R. & Klopper, J (2011). The impact of beta1 integrin signalling on adult human hair follicle epithelial progenitor cell viability. EXPERIMENTAL DERMATOLOGY, 20(2), 208-208. eScholarID:126893
  • Flori, E., Mastrofrancesco, A., Kovacs, D., Ramot, Y., Briganti, S., Bellei, B., Paus, R. & Picardo, M (2011). 2,4,6-Octatrienoic acid is a novel promoter of melanogenesis and antioxidant defence in normal human melanocytes via PPAR-γ activation. Pigment Cell Melanoma Res, 24(4), 618-30. eScholarID:161146 | PMID:21762468 | DOI:10.1111/j.1755-148X.2011.00887.x
  • Flori, E., Mastrofrancesco, A., Kovacs, D., Ramot, Y., Briganti, S., Bellei, B., Paus, R. & Picardo, M (2011). 2,4,6-Octatrienoic acid is a novel promoter of melanogenesis and antioxidant defence in normal human melanocytes via PPAR-γ activation. Pigment Cell Melanoma Res, 24(4), 618-30. eScholarID:169037 | PMID:21762468 | DOI:10.1111/j.1755-148X.2011.00887.x
  • Gáspár, E., Nguyen-Thi, K., Hardenbicker, C., Tiede, S., Plate, C., Bodó, E., Knuever, J., Funk, W., Bíró, T. & Paus, R (2011). Thyrotropin-releasing hormone selectively stimulates human hair follicle pigmentation. J Invest Dermatol, 131(12), 2368-77. eScholarID:145546 | PMID:21956127 | DOI:10.1038/jid.2011.221
  • Gáspár, E., Nguyen-Thi, K., Hardenbicker, C., Tiede, S., Plate, C., Bodó, E., Knuever, J., Funk, W., Bíró, T. & Paus, R (2011). Thyrotropin-releasing hormone selectively stimulates human hair follicle pigmentation. J Invest Dermatol, 131(12), 2368-77. eScholarID:169068 | PMID:21956127 | DOI:10.1038/jid.2011.221
  • Geyfman, M., Gordon, W., Paus, R. & Andersen, B (2011). Identification of Telogen Markers Underscores that Telogen Is Far from a Quiescent Hair Cycle Phase. J Invest Dermatol, eScholarID:145525 | PMID:22089832 | DOI:10.1038/jid.2011.367
  • Hindocha, S., Iqbal, S., Farhatullah, S., Paus, R. & Bayat, A (2011). Characterization of stem cells in Dupuytren's disease. Br J Surg, 98(2), 308-15. eScholarID:161150 | PMID:21104823 | DOI:10.1002/bjs.7307
  • Hindocha, S., Iqbal, S., Farhatullah, S., Paus, R. & Bayat, A (2011). Characterization of stem cells in Dupuytren's disease. Br J Surg, 98(2), 308-15. eScholarID:169054 | PMID:21104823 | DOI:10.1002/bjs.7307
  • Kinori, M., Kloepper, J. & Paus, R (2011). Can the hair follicle become a model for studying selected aspects of human ocular immune privilege? Invest Ophthalmol Vis Sci, 52(7), 4447-58. eScholarID:161151 | PMID:21700717 | DOI:10.1167/iovs.10-7154
  • Kinori, M., Kloepper, J. & Paus, R (2011). Can the hair follicle become a model for studying selected aspects of human ocular immune privilege? Invest Ophthalmol Vis Sci, 52(7), 4447-58. eScholarID:169043 | PMID:21700717 | DOI:10.1167/iovs.10-7154
  • Knuver, J., Vidali, S., Poeggeler, B., Gspr, E., Br, T., Tth, B., Hellwig-Burgel, T., Klinger, M. & Paus, R (2011). Neuroendocrine control of mitochondrial function in human epidermis and hair follicles. EXPERIMENTAL DERMATOLOGY, 20(2), 169-169. eScholarID:126895
  • Langan, E., Griffiths, C. & Paus, R (2011). In search of the source of hyperprolactinaemia in systemic lupus erythematosus. Clin Exp Rheumatol, 29(6), 1060. eScholarID:145551 | PMID:22032729
  • Lau, K., Hedegaard, M., Kloepper, J., Paus, R., Wood, B. & Deckert, V (2011). Visualization and characterisation of defined hair follicle compartments by Fourier transform infrared (FTIR) imaging without labelling. J Dermatol Sci, 63(3), 191-8. eScholarID:145547 | PMID:21752602 | DOI:10.1016/j.jdermsci.2011.05.002
  • Lau, K., Hedegaard, M., Kloepper, J., Paus, R., Wood, B. & Deckert, V (2011). Visualization and characterisation of defined hair follicle compartments by Fourier transform infrared (FTIR) imaging without labelling. J Dermatol Sci, 63(3), 191-8. eScholarID:169052 | PMID:21752602 | DOI:10.1016/j.jdermsci.2011.05.002
  • Mardaryev, A., Meier, N., Poterlowicz, K., Sharov, A., Sharova, T., Ahmed, M., Rapisarda, V., Lewis, C., Fessing, M., Ruenger, T., Bhawan, J., Werner, S., Paus, R. & Botchkarev, V (2011). Lhx2 differentially regulates Sox9, Tcf4 and Lgr5 in hair follicle stem cells to promote epidermal regeneration after injury. Development, 138(22), 4843-52. eScholarID:145531 | PMID:22028024 | DOI:10.1242/dev.070284
  • Mardaryev, A., Meier, N., Poterlowicz, K., Sharov, A., Sharova, T., Ahmed, M., Rapisarda, V., Lewis, C., Fessing, M., Ruenger, T., Bhawan, J., Werner, S., Paus, R. & Botchkarev, V (2011). Lhx2 differentially regulates Sox9, Tcf4 and Lgr5 in hair follicle stem cells to promote epidermal regeneration after injury. Development, 138(22), 4843-52. eScholarID:161159 | PMID:22028024 | DOI:10.1242/dev.070284
  • Mardaryev, A., Meier, N., Poterlowicz, K., Sharov, A., Sharova, T., Ahmed, M., Rapisarda, V., Lewis, C., Fessing, M., Ruenger, T., Bhawan, J., Werner, S., Paus, R. & Botchkarev, V (2011). Lhx2 differentially regulates Sox9, Tcf4 and Lgr5 in hair follicle stem cells to promote epidermal regeneration after injury. Development, 138(22), 4843-52. eScholarID:169046 | PMID:22028024 | DOI:10.1242/dev.070284
  • Meier, N., Zhang, G., Schafer, T., Geissen, M., Emelianov, V., Kleinspehn, E., Augustin, M., Debus, S. & Paus, R (2011). An in vitro test system to study human epidermal wound healing in situ. EXPERIMENTAL DERMATOLOGY, 20(2), 168-168. eScholarID:126896
  • Paus, R (2011). A neuroendocrinological perspective on human hair follicle pigmentation. Pigment Cell Melanoma Res, 24(1), 89-106. eScholarID:161147 | PMID:21108769 | DOI:10.1111/j.1755-148X.2010.00808.x
  • Paus, R (2011). A neuroendocrinological perspective on human hair follicle pigmentation. Pigment Cell Melanoma Res, 24(1), 89-106. eScholarID:169035 | PMID:21108769 | DOI:10.1111/j.1755-148X.2010.00808.x
  • Ramot, Y., Tiede, S., Bíró, T., Abu Bakar, M., Sugawara, K., Philpott, M., Harrison, W., Pietilä, M. & Paus, R (2011). Spermidine promotes human hair growth and is a novel modulator of human epithelial stem cell functions. PLoS One, 6(7), e22564. eScholarID:145536 | PMID:21818338 | DOI:10.1371/journal.pone.0022564
  • Ramot, Y., Tiede, S., Bíró, T., Abu Bakar, M., Sugawara, K., Philpott, M., Harrison, W., Pietilä, M. & Paus, R (2011). Spermidine promotes human hair growth and is a novel modulator of human epithelial stem cell functions. PLoS One, 6(7), e22564. eScholarID:169061 | PMID:21818338 | DOI:10.1371/journal.pone.0022564
  • Sebastian, A., Syed, F., McGrouther, D., Colthurst, J., Paus, R. & Bayat, A (2011). A novel in vitro assay for electrophysiological research on human skin fibroblasts: degenerate electrical waves downregulate collagen I expression in keloid fibroblasts. Exp Dermatol, 20(1), 64-8. eScholarID:161144 | PMID:20707813 | DOI:10.1111/j.1600-0625.2010.01150.x
  • Sebastian, A., Syed, F., McGrouther, D., Colthurst, J., Paus, R. & Bayat, A (2011). A novel in vitro assay for electrophysiological research on human skin fibroblasts: degenerate electrical waves downregulate collagen I expression in keloid fibroblasts. Exp Dermatol, 20(1), 64-8. eScholarID:169038 | PMID:20707813 | DOI:10.1111/j.1600-0625.2010.01150.x
  • Sugawara, K., Br, T., Kromminga, A., Tsuruta, D., Tth, B., Zimmer, A., Gibbs, B. & Paus, R (2011). Tonic inhibitory effects of endocannabinoids on human skin mast cellfunctions in situ by cannabinoid receptor 1 (CB1)-mediated signalling. EXPERIMENTAL DERMATOLOGY, 20(2), 168-168. eScholarID:126897
  • Sugawara, K., Dahlhoff, M., Paus, R. & Schneider, M (2011). Increased EGFR activity induces epidermal thickening and retards the initiation of hair follicle cycling in Dsk5 mice. EXPERIMENTAL DERMATOLOGY, 20(2), 205-205. eScholarID:126894
  • Tiede, S., Keckeis, P., Petschnik, A., Kruse, C. & Paus, R (2011). Functional importance and hormonal regulation of nestin expression in multi potent adult human skin progenitor cells in situ and in vitro. EXPERIMENTAL DERMATOLOGY, 20(2), 205-205. eScholarID:126892
  • Tóth, B., Dobrosi, N., Dajnoki, A., Czifra, G., Oláh, A., Szöllosi, A., Juhász, I., Sugawara, K., Paus, R. & Bíró, T (2011). Endocannabinoids modulate human epidermal keratinocyte proliferation and survival via the sequential engagement of cannabinoid receptor-1 and transient receptor potential vanilloid-1. J Invest Dermatol, 131(5), 1095-104. eScholarID:161155 | PMID:21248768 | DOI:10.1038/jid.2010.421
  • Tóth, B., Dobrosi, N., Dajnoki, A., Czifra, G., Oláh, A., Szöllosi, A., Juhász, I., Sugawara, K., Paus, R. & Bíró, T (2011). Endocannabinoids modulate human epidermal keratinocyte proliferation and survival via the sequential engagement of cannabinoid receptor-1 and transient receptor potential vanilloid-1. J Invest Dermatol, 131(5), 1095-104. eScholarID:169070 | PMID:21248768 | DOI:10.1038/jid.2010.421

2010

  • Al-Nuaimi, Y., Baier, G., Watson, R., Chuong, C. & Paus, R (2010). The cycling hair follicle as an ideal systems biology research model. Exp Dermatol, 19(8), 707-13. eScholarID:145537 | PMID:20590819 | DOI:10.1111/j.1600-0625.2010.01114.x
  • Anderson, J., Zorbas, J., Phillips, J., Harrison, J., Dawson, L., Bolt, S., Rea, S., Klatte, J., Paus, R., Zhu, B., Giles, N., Drummond, P., Wood, F. & Fear, M (2010). Systemic Decreases in Cutaneous Innervation after Burn Injury. J Invest Dermatol, eScholarID:79830 | PMID:20336082 | DOI:10.1038/jid.2010.47
  • Arck, P., Handjiski, B., Hagen, E., Pincus, M., Bruenahl, C., Bienenstock, J. & Paus, R (2010). Is there a 'gut-brain-skin axis'? Exp Dermatol, eScholarID:78036 | PMID:20113345 | DOI:10.1111/j.1600-0625.2009.01060.x
  • Arck, P., Handjiski, B., Hagen, E., Pincus, M., Bruenahl, C., Bienenstock, J. & Paus, R (2010). Is there a 'gut-brain-skin axis'? Exp Dermatol, 19(5), 401-5. eScholarID:145528 | PMID:20113345 | DOI:10.1111/j.1600-0625.2009.01060.x
  • Bodó, E., Kany, B., Gáspár, E., Knüver, J., Kromminga, A., Ramot, Y., Bíró, T., Tiede, S., van Beek, N., Poeggeler, B., Meyer, K., Wenzel, B. & Paus, R (2010). Thyroid-stimulating hormone, a novel, locally produced modulator of human epidermal functions, is regulated by thyrotropin-releasing hormone and thyroid hormones. Endocrinology, 151(4), 1633-42. eScholarID:145540 | PMID:20176727 | DOI:10.1210/en.2009-0306
  • Brosh, R., Sarig, R., Natan, E., Molchadsky, A., Madar, S., Bornstein, C., Buganim, Y., Shapira, T., Goldfinger, N., Paus, R. & Rotter, V (2010). p53-dependent transcriptional regulation of EDA2R and its involvement in chemotherapy-induced hair loss. FEBS Lett, 584(11), 2473-7. eScholarID:105316 | PMID:20434500 | DOI:10.1016/j.febslet.2010.04.058
  • Brosh, R., Sarig, R., Natan, E., Molchadsky, A., Madar, S., Bornstein, C., Buganim, Y., Shapira, T., Goldfinger, N., Paus, R. & Rotter, V (2010). p53-dependent transcriptional regulation of EDA2R and its involvement in chemotherapy-induced hair loss. FEBS Lett, 584(11), 2473-7. eScholarID:145548 | PMID:20434500 | DOI:10.1016/j.febslet.2010.04.058
  • Bundy, C., Griffiths, C., Paus, R. & Harries, M (2010). Illness perception, psychological distress and quality of life in patients with cicatricial alopecias. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 130, S67-S67. eScholarID:126925
  • Ernst, N., Tiede, S., Tronnier, V., Kruse, C., Zechel, C. & Paus, R (2010). An improved, standardised protocol for the isolation, enrichment and targeted neural differentiation of Nestin plus progenitors from adult human dermis. EXPERIMENTAL DERMATOLOGY, 19(6), 549-555. eScholarID:126914 | DOI:10.1111/j.1600-0625.2009.01041.x
  • Farman, N., Maubec, E., Poeggeler, B., Klatte, J., Jaisser, F. & Paus, R (2010). The mineralocorticoid receptor as a novel player in skin biology: beyond the renal horizon? Exp Dermatol, 19(2), 100-7. eScholarID:78046 | PMID:19925636 | DOI:10.1111/j.1600-0625.2009.01011.x
  • Fleger-Weckmann, A., Kloepper, J., Bechtel, M., Chen, Z., Langbein, L., Bloch, W., Paus, R. & Nischt, R (2010). The role of gamma l chain containing laminins for the formation and function of the dermo-epidermal basement membrane. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 130, S90-S90. eScholarID:126922
  • Gaspar E, Hardenbicker C, Bodo E, Wenzel B, Ramot Y, Funk W, Kromminga A, Paus R. (2010). Thyrotopin releasing hormone (TRH): a new player in human hair growth control. FASEB J, 24(2), 393-403. eScholarID:107411 | DOI:10.1096/fj.08-126417
  • Gilhar, A., d'Ovidio, R. & Paus, R (2010). An unexpected twist in alopecia areata pathogenesis:Are NK cells protective, and CD49b+T cells pathogenic? JOURNAL OF INVESTIGATIVE DERMATOLOGY, 130, S39-S39. eScholarID:126930
  • Harries MJ, Meyer KC, Chaudhry IH, Griffiths CE, Paus R. (2010). Does collapse of immune privilege in the hair follicle bulge play a role in the pathegenesis of primary cicatricial alopecia? Clin Exp Dermatol, 35(6), 637-44. eScholarID:107385
  • Harries, M. & Paus, R (2010). The pathogenesis of primary cicatricial alopecias. Am J Pathol, 177(5), 2152-62. eScholarID:105320 | PMID:20889564 | DOI:10.2353/ajpath.2010.100454
  • Harries, M. & Paus, R (2010). The pathogenesis of primary cicatricial alopecias. Am J Pathol, 177(5), 2152-62. eScholarID:145538 | PMID:20889564 | DOI:10.2353/ajpath.2010.100454
  • Harries, M. & Paus, R (2010). The pathogenesis of primary cicatricial alopecias. Am J Pathol, 177(5), 2152-62. eScholarID:169064 | PMID:20889564 | DOI:10.2353/ajpath.2010.100454
  • Harries, M. & Paus, R (2010). The Pathogenesis of Primary Cicatricial Alopecias. AMERICAN JOURNAL OF PATHOLOGY, 177(5), 2152-2162. eScholarID:126935 | DOI:10.2353/ajpath.2010.100454
  • Harries, M., Chaudhry, I., Paus, R. & Griffiths, C (2010). Cicatricial alopecias: a retrospective analysis of 92 cases from one U.K. centre. BRITISH JOURNAL OF DERMATOLOGY, 163, 43-44. eScholarID:126918
  • Harries, M., Griffiths, C. & Paus, R (2010). Immunopathology of "neutrophilic" primary cicatricial alopecias. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 130, S15-S15. eScholarID:126931
  • Harries, M., Sun, J., Paus, R. & King, L (2010). Management of alopecia areata. BMJ, 341, c3671. eScholarID:169051 | PMID:20656774 | DOI:10.1136/bmj.c3671
  • Hoi, C., Lee, S., Lu, S., McDermitt, D., Osorio, K., Piskun, C., Peters, R., Paus, R. & Tumbar, T (2010). Runx1 directly promotes proliferation of hair follicle stem cells and epithelial tumor formation in mouse skin. Mol Cell Biol, 30(10), 2518-36. eScholarID:145533 | PMID:20308320 | DOI:10.1128/MCB.01308-09
  • Holub, B., Kloepper, J., Rauch, I., Kofler, B. & Paus, R (2010). GALANIN INHIBITS HAIR FOLLICLE GROWTH. NEUROPEPTIDES, 44(6), 541-541. eScholarID:126937
  • Imanishi, H., Tsuruta, D., Tateishi, C., Sugawara, K., Paus, R., Tsuji, T., Ishii, M., Ikeda, K., Kunimoto, H., Nakajima, K., Jones, J. & Kobayashi, H (2010). Laminin-511, inducer of hair growth, is down-regulated and its suppressor in hair growth, laminin-332 up-regulated in chemotherapy-induced alopecia (vol 58, pg 43, 2010). JOURNAL OF DERMATOLOGICAL SCIENCE, 60(1), 58-58. eScholarID:126934 | DOI:10.1016/j.jdermsci.2010.08.001
  • Imanishi, H., Tsuruta, D., Tateishi, C., Sugawara, K., Paus, R., Tsuji, T., Ishii, M., Ikeda, K., Kunimoto, H., Nakajima, K., Jones, J. & Kobayashi, H (2010). Laminin-511, inducer of hair growth, is down-regulated and its suppressor in hair growth, laminin-332 up-regulated in chemotherapy-induced alopecia. J Dermatol Sci, 58(1), 43-54. eScholarID:145530 | PMID:20211547 | DOI:10.1016/j.jdermsci.2010.02.005
  • Iqbal, S., Syed, F., McGrouther, D., Paus, R. & Bayat, A (2010). Differential distribution of haematopoietic and nonhaematopoietic progenitor cells in intralesional and extralesional keloid: do keloid scars provide a niche for nonhaematopoietic mesenchymal stem cells? Br J Dermatol, eScholarID:84795 | PMID:20192956 | DOI:10.1111/j.1365-2133.2010.09738.x
  • Iqbal, S., Syed, F., McGrouther, D., Paus, R. & Bayat, A (2010). Differential distribution of haematopoietic and nonhaematopoietic progenitor cells in intralesional and extralesional keloid: do keloid scars provide a niche for nonhaematopoietic mesenchymal stem cells? Br J Dermatol, 162(6), 1377-83. eScholarID:145522 | PMID:20192956 | DOI:10.1111/j.1365-2133.2010.09738.x
  • Ito, N., Sugawara, K., Bodó, E., Takigawa, M., van Beek, N., Ito, T. & Paus, R (2010). Corticotropin-releasing hormone stimulates the in situ generation of mast cells from precursors in the human hair follicle mesenchyme. J Invest Dermatol, 130(4), 995-1004. eScholarID:78041 | PMID:20043013 | DOI:10.1038/jid.2009.387
  • Kloepper, J., Bíró, T., Paus, R. & Cseresnyés, Z (2010). Point scanning confocal microscopy facilitates 3D human hair follicle imaging in tissue sections. Exp Dermatol, eScholarID:84784 | PMID:20545762 | DOI:10.1111/j.1600-0625.2010.01110.x
  • Knuever, J., Poeggeler, B., Gaspar, E., Biro, T., Toth, B., Hellwig-Buergel, T., Klinger, M. & Paus, R (2010). Thyrotropin-releasing hormone (TRH) controls mitochondrial function and biogenesis in human keratinocytes in situ. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 130, S20-S20. eScholarID:126929
  • Langan EA, Ramot Y, Goffin V, Griffiths CE, Foitzik K, Paus R. (2010). Mind the (gender) gap: does prolactin exert gender and/or site-specific effects on the human hair follicle? J Invest Dermatol, 130(3), 886-91. eScholarID:107364 | DOI:10.1038/jid.2009.340
  • Langan, E. & Paus, R (2010). Female pattern hair loss: beyond an androgenic aetiology? BRITISH JOURNAL OF DERMATOLOGY, 163(5), 1140-1141. eScholarID:126933 | DOI:10.1111/j.1365-2133.2010.09955.x
  • Langan, E., Foitzik-Lau, K., Goffin, V., Ramot, Y. & Paus, R (2010). Prolactin: an emerging force along the cutaneous-endocrine axis. Trends Endocrinol Metab, 21(9), 569-77. eScholarID:161171 | PMID:20598901 | DOI:10.1016/j.tem.2010.06.001
  • Langan, E., Ramot, Y., Hanning, A., Poeggeler, B., Bíró, T., Gaspar, E., Funk, W., Griffiths, C. & Paus, R (2010). Thyrotropin-releasing hormone and oestrogen differentially regulate prolactin and prolactin receptor expression in female human skin and hair follicles in vitro. Br J Dermatol, 162(5), 1127-31. eScholarID:145541 | PMID:20302576 | DOI:10.1111/j.1365-2133.2010.09676.x
  • Lau, K., Matthaeus, C., Popp, J., Wood, B., Kloepper, J., Paus, R. & Deckert, V (2010). Label-Free Non-Destructive Identification of Stem Cells in the Hair Follicle with Confocal Raman Spectrocopy. XXII INTERNATIONAL CONFERENCE ON RAMAN SPECTROSCOPY, 1267, 360-361. eScholarID:126916 | DOI:10.1063/1.3482558
  • Lefever, T., Pedersen, E., Basse, A., Paus, R., Quondamatteo, F., Stanley, A., Langbein, L., Wu, X., Wehland, J., Lommel, S. & Brakebusch, C (2010). N-WASP is a novel regulator of hair-follicle cycling that controls antiproliferative TGF{beta} pathways. J Cell Sci, 123(Pt 1), 128-40. eScholarID:78042 | PMID:20016073 | DOI:10.1242/jcs.053835
  • Lyne, L., Harries, M., Chaudhry, I., Farjo, B., Farjo, N., de Farias, D., Tosti, A., Griffiths, C. & Paus, R (2010). Lichen planopilaris following hair transplantation and facelift surgery. BRITISH JOURNAL OF DERMATOLOGY, 163, 31-31. eScholarID:126919
  • Meier, N., Pattwell, D., Zhang, G., Loconto, J., Geissen, M., Schafer, T., Emelianov, V., Klopper, J., Paredes, R., Augustin, M., Debus, S., Amaya, E. & Paus, R (2010). Novel neuroendocrine controls of amphibian and human skin reepithelialisation through thyrotropin-releasing hormone (TRH) and bombesin and its mammalian homologues. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 130, S88-S88. eScholarID:126926
  • Meyer, K., Tiede, S., Harries, M., Kloepper, J. & Paus, R (2010). IFN-gamma induces bulge immunoprivilege collapse and may cause epithelial stem cell exhaust. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 130, S42-S42. eScholarID:126928
  • Paus, R (2010). Exploring the "thyroid-skin connection": concepts, questions, and clinical relevance. J Invest Dermatol, 130(1), 7-10. eScholarID:78043 | PMID:20010860 | DOI:10.1038/jid.2009.359
  • Paus, R (2010). Neuroendocrinology of the hair follicle: A hitchhiker's guide through the skin galaxy. EXPERIMENTAL DERMATOLOGY, 19(6), 557-557. eScholarID:126913
  • Petukhova, L., Duvic, M., Hordinsky, M., Norris, D., Price, V., Shimomura, Y., Kim, H., Singh, P., Lee, A., Chen, W., Meyer, K., Paus, R., Jahoda, C., Amos, C., Gregersen, P. & Christiano, A (2010). Genome-wide association study in alopecia areata implicates both innate and adaptive immunity. Nature, 466(7302), 113-7. eScholarID:161169 | PMID:20596022 | DOI:10.1038/nature09114
  • Poeggeler, B., Knuever, J., Gáspár, E., Bíró, T., Klinger, M., Bodó, E., Wiesner, R., Wenzel, B. & Paus, R (2010). Thyrotropin powers human mitochondria. FASEB J, eScholarID:78039 | PMID:20075194 | DOI:10.1096/fj.09-147728
  • Rakers, S., Gebert, M., Uppalapati, S., Meyer, W., Maderson, P., Sell, A., Kruse, C. & Paus, R (2010). 'Fish matters': the relevance of fish skin biology to investigative dermatology. Exp Dermatol, eScholarID:78035 | PMID:20158518 | DOI:10.1111/j.1600-0625.2009.01059.x
  • Ramot, Y., Bíró, T., Tiede, S., Tóth, B., Langan, E., Sugawara, K., Foitzik, K., Ingber, A., Goffin, V., Langbein, L. & Paus, R (2010). Prolactin--a novel neuroendocrine regulator of human keratin expression in situ. The FASEB journal, 24(6), 1768. eScholarID:78037 | PMID:20103718 | DOI:10.1096/fj.09-146415
  • Ramot, Y., Pietilä, M., Giuliani, G., Rinaldi, F., Alhonen, L. & Paus, R (2010). Polyamines and hair: a couple in search of perfection. Exp Dermatol, 19(9), 784-90. eScholarID:161170 | PMID:20629736 | DOI:10.1111/j.1600-0625.2010.01111.x
  • Sayama, K., Kajiya, K., Sugawara, K., Sato, S., Hirakawa, S., Shirakata, Y., Hanakawa, Y., Dai, X., Ishimatsu-Tsuji, Y., Metzger, D., Chambon, P., Akira, S., Paus, R., Kishimoto, J. & Hashimoto, K (2010). Inflammatory mediator TAK1 regulates hair follicle morphogenesis and anagen induction shown by using keratinocyte-specific TAK1-deficient mice. PLoS One, 5(6), e11275. eScholarID:161158 | PMID:20585657 | DOI:10.1371/journal.pone.0011275
  • Schneider, M. & Paus, R (2010). Sebocytes, multifaceted epithelial cells: lipid production and holocrine secretion. Int J Biochem Cell Biol, 42(2), 181-5. eScholarID:78044 | PMID:19944183 | DOI:10.1016/j.biocel.2009.11.017
  • Seeliger, S., Buddenkotte, J., Schmidt-Choudhury, A., Rosignoli, C., Shpacovitch, V., von Arnim, U., Metze, D., Rukwied, R., Schmelz, M., Paus, R., Voegel, J., Schmidt, W. & Steinhoff, M (2010). Pituitary adenylate cyclase activating polypeptide: an important vascular regulator in human skin in vivo. Am J Pathol, 177(5), 2563-75. eScholarID:161162 | PMID:20889562 | DOI:10.2353/ajpath.2010.090941
  • Seeliger, S., Buddenkotte, J., Schmidt-Choudhury, A., Rosignoli, C., Shpacovitch, V., von Arnim, U., Metze, D., Rukwied, R., Schmelz, M., Paus, R., Voegel, J., Schmidt, W. & Steinhoff, M (2010). Pituitary adenylate cyclase activating polypeptide: an important vascular regulator in human skin in vivo. Am J Pathol, 177(5), 2563-75. eScholarID:169057 | PMID:20889562 | DOI:10.2353/ajpath.2010.090941
  • Sugawara, K., Hundt, T., Emelianov, V., Koennecke, M., Wollenberg, B. & Paus, R (2010). Human skin and hair follicle versus nasal polyp organ culture as clinically and physiologically relevant model systems for studying normal human connective tissue-type and mucosal-type mast cell biology in situ. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 130, S43-S43. eScholarID:126927
  • Sugawara, K., Schneider, M., Dahlhoff, M., Kloepper, J. & Paus, R (2010). Cutaneous consequences of inhibiting EGF receptor signaling in vivo: normal hair follicle development, but retarded hair cycle induction and inhibition of adipocyte growth in Egfr(Wa5) mice. J Dermatol Sci, 57(3), 155-61. eScholarID:78040 | PMID:20060271 | DOI:10.1016/j.jdermsci.2009.12.004
  • Tauchi, M., Fuchs, T., Kellenberger, A., Woodward, D., Paus, R. & Lütjen-Drecoll, E (2010). Characterization of an in vivo model for the study of eyelash biology and trichomegaly: mouse eyelash morphology, development, growth cycle, and anagen prolongation by bimatoprost. Br J Dermatol, 162(6), 1186-97. eScholarID:145520 | PMID:20346040 | DOI:10.1111/j.1365-2133.2010.09685.x
  • Thiryayi, S., Harries, M., White, E., Griffiths, C., Paus, R. & Chaudhry, I (2010). Histopathological review of 78 cases of cicatricial alopecia at one U. K. centre. BRITISH JOURNAL OF DERMATOLOGY, 163, 93-94. eScholarID:126917
  • Tiede, S., Bohm, K., Meier, N., Funk, W. & Paus, R (2010). Endocrine controls of primary adult human stem cell biology: thyroid hormones stimulate keratin 15 expression, apoptosis, and differentiation in human hair follicle epithelial stem cells in situ and in vitro. Eur J Cell Biol, 89(10), 769-77. eScholarID:161160 | PMID:20656376 | DOI:10.1016/j.ejcb.2010.06.002
  • Tiede, S., Plate, C., Meier, N., Abu Bakar, M. & Paus, R (2010). Vitamin-D3 modulates human hair follicle epithelial progenitor cells in situ and in vitro. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 130, S89-S89. eScholarID:126921
  • van de Vosse, E., Ottenhoff, T., de Paus, R., Verhard, E., de Boer, T., van Dissel, J. & Kuijpers, T (2010). Mycobacterium bovis BCG-itis and cervical lymphadenitis due to Salmonella enteritidis in a patient with complete interleukin-12/-23 receptor beta1 deficiency. Infection, 38(2), 128-30. eScholarID:145545 | PMID:20213287 | DOI:10.1007/s15010-009-9222-0
  • Pattwell DM, Lynaugh KJ, Watson RE, Paus R. (2010). HaCaT keratinocytes express functional receptors for thyroid-stimulating hormone. J Dermatol Sci, 59(1), 52-55. eScholarID:84793
  • Pincus M, Keil T, Rücke M, Bruenahl C, Magdorf K, Klapp BF, Douglas AJ, Paus R, Wahn U, Arck P. (2010). Fetal origin of atopic dermatitis. J Allergy Clin Immunol, 125(1), 3. eScholarID:84798

2009

  • Antsiferova M, Klatte J, Bodó E, Paus RR, Jorcano J, Matzuk M, Werner S, Kögel H. (2009). Keratinocyte-derived follistatin regulates epidermal homeostasis and wound repair. Lab Invest, 89( 2), 131-41. eScholarID:1d18507 | DOI:10.1038/labinvest.2008.120
  • Bíró, T., Tóth, B., Haskó, G., Paus, R. & Pacher, P (2009). The endocannabinoid system of the skin in health and disease: novel perspectives and therapeutic opportunities. Trends Pharmacol Sci, 30(8), 411-20. eScholarID:39245 | PMID:19608284 | DOI:10.1016/j.tips.2009.05.004
  • Bodó E, van Beek N, Naumann V, Ohnemus U, Brzoska T, Abels C, Paus RR. (2009). Modulation of chemotherapy-induced human hair follicle damage by 17-beta estradiol and prednisolone: potential stimulators of normal hair regrowth by "dystrophic catagen" promotion? J Invest Dermatol, 129( 2), 506-9. eScholarID:1d18518 | DOI:10.1038/jid.2008.228
  • Bodó, E., Wiersma, F., Funk, W., Kromminga, A., Jelkmann, W. & Paus, R (2009). Does erythropoietin modulate human hair follicle melanocyte activities in situ? Exp Dermatol, eScholarID:39241 | PMID:19645852 | DOI:10.1111/j.1600-0625.2009.00938.x
  • Harries MJ, Trueb RM, Tosti A, Messenger AG, Chaudhry I, Whiting DA, Sinclair R, Griffiths CEM, Paus RR. (2009). How not to get scar(r)ed: pointers to the correct diagnosis in patients with suspected primary cicatricial alopecia. Br J Dermatol, eScholarID:1d18484 | DOI:10.1111/j.1365-2133.2008.09008.x
  • Harries, M. & Paus, R (2009). Scarring alopecia and the PPAR-gamma connection. J Invest Dermatol, 129(5), 1066-70. eScholarID:39258 | PMID:19369934 | DOI:10.1038/jid.2008.425
  • Kloepper, J., Sugawara, K., Al-Nuaimi, Y., Gáspár, E., van Beek, N. & Paus, R (2009). Methods in hair research: how to objectively distinguish between anagen and catagen in human hair follicle organ culture. Exp Dermatol, eScholarID:39235 | PMID:19725870 | DOI:10.1111/j.1600-0625.2009.00939.x
  • Lau, K., Paus, R., Tiede, S., Day, P. & Bayat, A (2009). Exploring the role of stem cells in cutaneous wound healing. Exp Dermatol, eScholarID:39236 | PMID:19719838 | DOI:10.1111/j.1600-0625.2009.00942.x
  • Lin, K., Kumar, V., Geyfman, M., Chudova, D., Ihler, A., Smyth, P., Paus, R., Takahashi, J. & Andersen, B (2009). Circadian clock genes contribute to the regulation of hair follicle cycling. PLoS Genet, 5(7), e1000573. eScholarID:39242 | PMID:19629164 | DOI:10.1371/journal.pgen.1000573
  • Lu Z, Fischer TW, Hasse S, Sugawara K, Kamenisch Y, Krengel S, Funk W, Berneburg M, Paus RR. (2009). Profiling the Response of Human Hair Follicles to Ultraviolet Radiation. J Invest Dermatol, eScholarID:1d18505 | DOI:10.1038/jid.2008.418
  • Meyer K, Brzoska T, Abels C, Paus RR. (2009). The alpha-melanocyte stimulating hormone-related tripeptide K(D)PT stimulates human hair follicle pigmentation in situ under proinflammatory conditions. Br J Dermatol, 160( 2), 433-7. eScholarID:1d18510 | DOI:10.1111/j.1365-2133.2008.08872.x
  • Ohyama, M., Zheng, Y., Paus, R. & Stenn, K (2009). The mesenchymal component of hair follicle neogenesis: background, methods and molecular characterization. Exp Dermatol, eScholarID:39239 | PMID:19650868 | DOI:10.1111/j.1600-0625.2009.00935.x
  • Paus RR, Bodó E, Kromminga A, Jelkmann W. (2009). Erythropoietin and the skin: a role for epidermal oxygen sensing? Bioessays, 31( 3), eScholarID:1d19891 | DOI:10.1002/bies.200800192
  • Paus, R. & Arck, P (2009). Neuroendocrine perspectives in alopecia areata: does stress play a role? J Invest Dermatol, 129(6), 1324-6. eScholarID:39255 | PMID:19434088 | DOI:10.1038/jid.2009.111
  • Petschnik, A., Klatte, J., Evers, L., Kruse, C., Paus, R. & Danner, S (2009). Phenotypic indications that human sweat glands are a rich source of nestin positive stem cell populations. Br J Dermatol, eScholarID:39233 | PMID:19772523 | DOI:10.1111/j.1365-2133.2009.09512.x
  • Plonka, P., Passeron, T., Brenner, M., Tobin, D., Shibahara, S., Thomas, A., Slominski, A., Kadekaro, A., Hershkovitz, D., Peters, E., Nordlund, J., Abdel-Malek, Z., Takeda, K., Paus, R., Ortonne, J., Hearing, V. & Schallreuter, K (2009). What are melanocytes really doing all day long...? Exp Dermatol, 18(9), 799-819. eScholarID:39237 | PMID:19659579 | DOI:10.1111/j.1600-0625.2009.00912.x
  • Poeggeler, B., Bodó, E., Nadrowitz, R., Dunst, J. & Paus, R (2009). A simple assay for the study of human hair follicle damage induced by ionizing irradiation. Exp Dermatol, eScholarID:78045 | PMID:19925637 | DOI:10.1111/j.1600-0625.2009.01009.x
  • Poeggeler, B., Schulz, C., Pappolla, M., Bodó, E., Tiede, S., Lehnert, H. & Paus, R (2009). Leptin and the skin: a new frontier. Exp Dermatol, eScholarID:39249 | PMID:19601981 | DOI:10.1111/j.1600-0625.2009.00930.x
  • Ramot Y, Gáspár E, Dendorfer A, Langbein L, Paus RR. (2009). The 'melanocyte-keratin' mystery revisited: neither normal human epidermal nor hair follicle melanocytes express keratin 16 or keratin 6 in situ. Br J Dermatol, eScholarID:1d19885 | DOI:10.1111/j.1365-2133.2009.09294.x
  • Ramot, Y., Paus, R., Tiede, S. & Zlotogorski, A (2009). Endocrine controls of keratin expression. Bioessays, 31(4), 389-99. eScholarID:39263 | PMID:19274655 | DOI:10.1002/bies.200800121
  • Reithmayer, K., Meyer, K., Kleditzsch, P., Tiede, S., Uppalapati, S., Gläser, R., Harder, J., Schröder, J. & Paus, R (2009). Human hair follicle epithelium has an antimicrobial defence system that includes the inducible antimicrobial peptide psoriasin (S100A7) and RNase 7. Br J Dermatol, 161(1), 78-89. eScholarID:39256 | PMID:19416233 | DOI:10.1111/j.1365-2133.2009.09154.x
  • Rückert, R, Brandt, K, Ernst, M, Marienfeld, K, Csernok, E, Metzler, C, Budagian, V, Bulanova, E, Paus, RR, Bulfone-Paus, S. (2009). Interleukin-15 stimulates macrophages to activate CD4+ T cells: a role in the pathogenesis of rheumatoid arthritis? Immunology, 126( 1), 63-73. eScholarID:1d18523 | DOI:10.1111/j.1365-2567.2008.02878.x
  • Schneider M, Schmidt-Ullrich R, Paus RR. (2009). The hair follicle as a dynamic miniorgan. Curr Biol, 19( 3), R132-42. eScholarID:1d18504 | DOI:10.1016/j.cub.2008.12.005
  • Stelekati, E., Bahri, R., D'Orlando, O., Orinska, Z., Mittrücker, H., Langenhaun, R., Glatzel, M., Bollinger, A., Paus, R. & Bulfone-Paus, S (2009). Mast cell-mediated antigen presentation regulates CD8+ T cell effector functions. Immunity, 31(4), 665-76. eScholarID:85386 | PMID:19818652 | DOI:10.1016/j.immuni.2009.08.022
  • Tiede S, Ernst N, Bayat A, Paus RR, Tronnier V, Zechel C. (2009). Basic fibroblast growth factor: a potential new therapeutic tool for the treatment of hypertrophic and keloid scars. Ann Anat, 191( 1), 33-44. eScholarID:1d18493 | DOI:10.1016/j.aanat.2008.10.001
  • Tiede S, Kloepper JE, Ernst N, Poeggeler B, Kruse C, Paus RR. (2009). Nestin in Human Skin: Exclusive Expression in Intramesenchymal Skin Compartments and Regulation by Leptin. J Invest Dermatol, eScholarID:1d19884 | DOI:10.1038/jid.2009.148
  • Tiede, S., Koop, N., Kloepper, J., Fässler, R. & Paus, R (2009). Non-Viral in Situ GFP-Labelling and Culture of Primary, Adult Human Hair Follicle Epithelial Progenitor Cells. Stem Cells, eScholarID:39234 | PMID:19750535 | DOI:10.1002/stem.213
  • Tóth, B, Géczy, T, Griger, Z, Dózsa, A, Seltmann, H, Kovács, L, Nagy, L, Zouboulis, C, Paus, RR, Bíró, T. (2009). Transient receptor potential vanilloid-1 signaling as a regulator of human sebocyte biology. J Invest Dermatol, 129( 2), 329-39. eScholarID:1d18516 | DOI:10.1038/jid.2008.258
  • Wood, JJ.M.., Decker, H, Hartmann, H, Chavan, BB, Rokos, H, Spencer, J, Hasse, S, Thornton, MR, Shalbaf, M, Paus, RR, Schallreuter, K. (2009). Senile hair graying: H2O2-mediated oxidative stress affects human hair color by blunting methionine sulfoxide repair. FASEB J, 23( 7), eScholarID:1d19892 | DOI:10.1096/fj.08-125435
  • Zhang, Y., Tomann, P., Andl, T., Gallant, N., Huelsken, J., Jerchow, B., Birchmeier, W., Paus, R., Piccolo, S., Mikkola, M., Morrisey, E., Overbeek, P., Scheidereit, C., Millar, S. & Schmidt-Ullrich, R (2009). Reciprocal requirements for EDA/EDAR/NF-kappaB and Wnt/beta-catenin signaling pathways in hair follicle induction. Dev Cell, 17(1), 49-61. eScholarID:39243 | PMID:19619491 | DOI:10.1016/j.devcel.2009.05.011

2008

  • Adly MA, Assaf HA, Pertile P, Hussein MR, Paus R. (2008). Expression patterns of the glial cell line-derived neurotrophic factor, neurturin, their cognate receptors GFRalpha-1, GFRalpha-2, and a common signal transduction element c-Ret in the human skin hair follicles. Journal of the American Academy of Dermatology, 58(2), 238-250. eScholarID:38506 | DOI:10.1016/j.jaad.2007.10.014
  • Arck P, Gilhar A, Bienenstock J, Paus RR. (2008). The alchemy of immune privilege explored from a neuroimmunological perspective. Curr Opin Pharmacol, 8( 4), 480-9. eScholarID:1d18520 | DOI:10.1016/j.coph.2008.06.003
  • Bodó, E, Kromminga, A, Bíró, T, Borbíró, I, Gáspár, E, Zmijewski, M, van Beek, N, Langbein, L, Slominski, A, Paus, RR. (2008). Human Female Hair Follicles Are a Direct, Nonclassical Target for Thyroid-Stimulating Hormone. J Invest Dermatol, eScholarID:1d18508 | DOI:10.1038/jid.2008.361
  • Bulfone-Paus, S. & Paus, R (2008). Osteopontin as a new player in mast cell biology. Eur J Immunol, 38(2), 338-41. eScholarID:38215 | PMID:18228246 | DOI:10.1002/eji.200738131
  • Dobrosi, N, Tóth, B, Nagy, G, Dózsa, A, Géczy, T, Nagy, L, Zouboulis, C, Paus, RR, Kovács, L, Bíró, T. (2008). Endocannabinoids enhance lipid synthesis and apoptosis of human sebocytes via cannabinoid receptor-2-mediated signaling. FASEB J, 22( 10), 3685-95. eScholarID:1d18521 | DOI:10.1096/fj.07-104877
  • Duitman E, Orinska Z, Bulanova E, Paus RR, Bulfone-Paus S. (2008). How a cytokine is chaperoned through the secretory pathway by complexing with its own receptor: lessons from interleukin-15 (IL-15)/IL-15 receptor alpha. Mol Cell Biol, 28( 15), 4851-61. eScholarID:1d18525 | DOI:10.1128/MCB.02178-07
  • Fischer T, Slominski A, Zmijewski M, Reiter R, Paus RR. (2008). Melatonin as a major skin protectant: from free radical scavenging to DNA damage repair. Exp Dermatol, 17( 9), 713-30. eScholarID:1d18519 | DOI:10.1111/j.1600-0625.2008.00767.x
  • Fischer, T., Slominski, A., Tobin, D. & Paus, R (2008). Melatonin and the hair follicle. J Pineal Res, 44(1), 1-15. eScholarID:38220 | PMID:18078443 | DOI:10.1111/j.1600-079X.2007.00512.x
  • Foitzik K, Langan EA, Paus RR. (2008). Prolactin and the Skin: A Dermatological Perspective on an Ancient Pleiotropic Peptide Hormone. J Invest Dermatol, eScholarID:1d18506 | DOI:10.1038/jid.2008.348
  • Hadshiew I, Barre K, Bódó E, Funk W, Paus RR. (2008). T-oligos as differential modulators of human scalp hair growth and pigmentation: a new "time lapse system" for studying human skin and hair follicle biology in vitro? Arch Dermatol Res, 300( 4), 155-9. eScholarID:1d18528 | DOI:10.1007/s00403-008-0833-6
  • Harries M, Sinclair R, Macdonald-Hull S, Whiting D, Griffiths CEM, Paus RR. (2008). Management of primary cicatricial alopecias: options for treatment. Br J Dermatol, 159( 1), 1-22. eScholarID:1d18207 | DOI:10.1111/j.1365-2133.2008.08591.x
  • Harries MJ, Meyer KC, Paus RR. (2008). Hair loss as a result of cutaneous autoimmunity: Frontiers in the immunopathogenesis of primary cicatricial alopecia. Autoimmun Rev, eScholarID:1d18511 | DOI:10.1016/j.autrev.2008.09.003
  • Havlickova, B, Bíró, T, Mescalchin, A, Tschirschmann, M, Mollenkopf, H, Bettermann, A, Pertile, P, Lauster, R, Bodó, E, Paus, RR. (2008). A Human Folliculoid Microsphere Assay for Exploring Epithelial- Mesenchymal Interactions in the Human Hair Follicle. J Invest Dermatol, eScholarID:1d18512 | DOI:10.1038/jid.2008.315
  • Ito T, Meyer K, Ito N, Paus RR. (2008). Immune privilege and the skin. Curr Dir Autoimmun, 10, 27-52. eScholarID:1d18526 | DOI:10.1159/000131412
  • Ito, T., Ito, N., Saatoff, M., Hashizume, H., Fukamizu, H., Nickoloff, B., Takigawa, M. & Paus, R (2008). Maintenance of hair follicle immune privilege is linked to prevention of NK cell attack. J Invest Dermatol, 128(5), 1196-206. eScholarID:38216 | PMID:18160967 | DOI:10.1038/sj.jid.5701183
  • Joachim R, Handjiski B, Blois S, Hagen E, Paus RR, Arck P. (2008). Stress-induced neurogenic inflammation in murine skin skews dendritic cells towards maturation and migration: key role of intercellular adhesion molecule-1/leukocyte function-associated antigen interactions. Am J Pathol, 173( 5), 1379-88. eScholarID:1d18513 | DOI:10.2353/ajpath.2008.080105
  • Kajahn J, Gorjup E, Tiede S, von Briesen H, Paus R, Kruse C, Danner S. (2008). Skin-derived human adult stem cells surprisingly share many features with human pancreatic stem cells. European Journal of Cell Biology, 87(1), 39-46. eScholarID:39175 | DOI:10.1016/j.ejcb.2007.07.004
  • Kloepper J, Tiede S, Brinckmann J, Reinhardt D, Meyer W, Faessler R, Paus RR. (2008). Immunophenotyping of the human bulge region: the quest to define useful in situ markers for human epithelial hair follicle stem cells and their niche. Exp Dermatol, 17( 7), 592-609. eScholarID:1d18522 | DOI:10.1111/j.1600-0625.2008.00720.x
  • Kloepper, J., Hendrix, S., Bodó, E., Tiede, S., Humphries, M., Philpott, M., Fässler, R. & Paus, R (2008). Functional role of beta 1 integrin-mediated signalling in the human hair follicle. Exp Cell Res, 314(3), 498-508. eScholarID:38219 | PMID:18155697 | DOI:10.1016/j.yexcr.2007.10.030
  • Meyer K, Klatte J, Dinh H, Harries M, Reithmayer K, Meyer W, Sinclair R, Paus RR. (2008). Evidence that the bulge region is a site of relative immune privilege in human hair follicles. Br J Dermatol, 159( 5), 1077-85. eScholarID:1d18515 | DOI:10.1111/j.1365-2133.2008.08818.x
  • Paus RR, Arck P, Tiede S. (2008). (Neuro-)endocrinology of epithelial hair follicle stem cells. Mol Cell Endocrinol, 288( 1-2), 38-51. eScholarID:1d18527 | DOI:10.1016/j.mce.2008.02.023
  • Plonka, P., Michalczyk, D., Popik, M., Handjiski, B. & Paus, R (2008). Electron paramagnetic resonance (EPR) spectroscopy for investigating murine telogen skin after spontaneous or depilation-induced hair growth. J Dermatol Sci, 49(3), 227-40. eScholarID:38222 | PMID:18061408 | DOI:10.1016/j.jdermsci.2007.09.010
  • Schallreuter KU, Bahadoran P, Picardo M, Slominski A, Elassiuty YE, Kemp EH, Giachino C, Liu JB, Luiten RM, Lambe T, Le Poole IC, Dammak I, Onay H, Zmijewski MA, Dell'Anna ML, Zeegers MP, Cornall RJ, Paus R, Ortonne JP, Westerhof W. (2008). Vitiligo pathogenesis: autoimmune disease, genetic defect, excessive reactive oxygen species, calcium imbalance, or what else? Experimental Dermatology, 17(2), 139-140. eScholarID:38429
  • Schneider M, Antsiferova M, Feldmeyer L, Dahlhoff M, Bugnon P, Hasse S, Paus RR, Wolf E, Werner S. (2008). Betacellulin regulates hair follicle development and hair cycle induction and enhances angiogenesis in wounded skin. J Invest Dermatol, 128( 5), 1256-65. eScholarID:1d18530 | DOI:10.1038/sj.jid.5701135
  • Schneider M, Werner S, Paus RR, Wolf E. (2008). Beyond wavy hairs: the epidermal growth factor receptor and its ligands in skin biology and pathology. Am J Pathol, 173( 1), 14-24. eScholarID:1d18524 | DOI:10.2353/ajpath.2008.070942
  • Semenova E, Koegel H, Hasse S, Klatte J, Slonimsky E, Bilbao D, Paus RR, Werner S, Rosenthal N. (2008). Overexpression of mIGF-1 in keratinocytes improves wound healing and accelerates hair follicle formation and cycling in mice. Am J Pathol, 173( 5), 1295-310. eScholarID:1d18514 | DOI:10.2353/ajpath.2008.071177
  • Slominski, A., Tobin, D., Zmijewski, M., Wortsman, J. & Paus, R (2008). Melatonin in the skin: synthesis, metabolism and functions. Trends Endocrinol Metab, 19(1), 17-24. eScholarID:38218 | PMID:18155917 | DOI:10.1016/j.tem.2007.10.007
  • Slominski, A., Wortsman, J., Paus, R., Elias, P., Tobin, D. & Feingold, K (2008). Skin as an endocrine organ: implications for its function. Drug Discov Today Dis Mech, 5(2), 137-144. eScholarID:39253 | PMID:19492070 | DOI:10.1016/j.ddmec.2008.04.004
  • van Beek N, Bodó E, Kromminga A, Gáspár E, Meyer K, Zmijewski M, Slominski A, Wenzel B, Paus RR. (2008). Thyroid hormones directly alter human hair follicle functions: anagen prolongation and stimulation of both hair matrix keratinocyte proliferation and hair pigmentation. J Clin Endocrinol Metab, 93( 11), 4381-8. eScholarID:1d18517 | DOI:10.1210/jc.2008-0283
  • Wu, Z, Meyer-Hoffert, U, Reithmayer, K, Paus, RR, Hansmann, B, He, Y, Bartels, J, Gläser, R, Harder, J, Schröder, J. (2008). Highly Complex Peptide Aggregates of the S100 Fused-Type Protein Hornerin Are Present in Human Skin. J Invest Dermatol, eScholarID:1d18509 | DOI:10.1038/jid.2008.370

2007

  • Beck, I., Müller, M., Mentlein, R., Sadowski, T., Mueller, M., Paus, R. & Sedlacek, R (2007). Matrix metalloproteinase-19 expression in keratinocytes is repressed by transcription factors Tst-1 and Skn-1a: implications for keratinocyte differentiation. J Invest Dermatol, 127(5), 1107-14. eScholarID:107479 | PMID:17195013 | DOI:10.1038/sj.jid.5700674
  • Bíró, T., Tóth, B., Marincsák, R., Dobrosi, N., Géczy, T. & Paus, R (2007). TRP channels as novel players in the pathogenesis and therapy of itch. Biochim Biophys Acta, 1772(8), 1004-21. eScholarID:107494 | PMID:17462867 | DOI:10.1016/j.bbadis.2007.03.002
  • Bodó, E., Kromminga, A., Funk, W., Laugsch, M., Duske, U., Jelkmann, W. & Paus, R (2007). Human hair follicles are an extrarenal source and a nonhematopoietic target of erythropoietin. FASEB J, 21(12), 3346-54. eScholarID:107467 | PMID:17540710 | DOI:10.1096/fj.07-8628com
  • Bodó, E., Tobin, D., Kamenisch, Y., Bíró, T., Berneburg, M., Funk, W. & Paus, R (2007). Dissecting the impact of chemotherapy on the human hair follicle: a pragmatic in vitro assay for studying the pathogenesis and potential management of hair follicle dystrophy. Am J Pathol, 171(4), 1153-67. eScholarID:107460 | PMID:17823286 | DOI:10.2353/ajpath.2007.061164
  • Foitzik, K., Hoting, E., Förster, T., Pertile, P. & Paus, R (2007). L-carnitine-L-tartrate promotes human hair growth in vitro. Exp Dermatol, 16(11), 936-45. eScholarID:107475 | PMID:17927577 | DOI:10.1111/j.1600-0625.2007.00611.x
  • Gilhar, A., Paus, R. & Kalish, R (2007). Lymphocytes, neuropeptides, and genes involved in alopecia areata. J Clin Invest, 117(8), 2019-27. eScholarID:107476 | PMID:17671634 | DOI:10.1172/JCI31942
  • Hasse, S., Chernyavsky, A., Grando, S. & Paus, R (2007). The M4 muscarinic acetylcholine receptor plays a key role in the control of murine hair follicle cycling and pigmentation. Life Sci, 80(24-25), 2248-52. eScholarID:107491 | PMID:17346754 | DOI:10.1016/j.lfs.2007.01.056
  • Joachim, R., Kuhlmei, A., Dinh, Q., Handjiski, B., Fischer, T., Peters, E., Klapp, B., Paus, R. & Arck, P (2007). Neuronal plasticity of the "brain-skin connection": stress-triggered up-regulation of neuropeptides in dorsal root ganglia and skin via nerve growth factor-dependent pathways. J Mol Med, 85(12), 1369-78. eScholarID:107480 | PMID:17639286 | DOI:10.1007/s00109-007-0236-8
  • Lu, Z., Hasse, S., Bodo, E., Rose, C., Funk, W. & Paus, R (2007). Towards the development of a simplified long-term organ culture method for human scalp skin and its appendages under serum-free conditions. Exp Dermatol, 16(1), 37-44. eScholarID:107493 | PMID:17181635 | DOI:10.1111/j.1600-0625.2006.00510.x
  • Orinska, Z., Maurer, M., Mirghomizadeh, F., Bulanova, E., Metz, M., Nashkevich, N., Schiemann, F., Schulmistrat, J., Budagian, V., Giron-Michel, J., Brandt, E., Paus, R. & Bulfone-Paus, S (2007). IL-15 constrains mast cell-dependent antibacterial defenses by suppressing chymase activities. Nat Med, 13(8), 927-34. eScholarID:107470 | PMID:17643110 | DOI:10.1038/nm1615
  • Peters, E., Liotiri, S., Bodó, E., Hagen, E., Bíró, T., Arck, P. & Paus, R (2007). Probing the effects of stress mediators on the human hair follicle: substance P holds central position. Am J Pathol, 171(6), 1872-86. eScholarID:107486 | PMID:18055548 | DOI:10.2353/ajpath.2007.061206
  • Sainte Marie, Y., Toulon, A., Paus, R., Maubec, E., Cherfa, A., Grossin, M., Descamps, V., Clemessy, M., Gasc, J., Peuchmaur, M., Glick, A., Farman, N. & Jaisser, F (2007). Targeted skin overexpression of the mineralocorticoid receptor in mice causes epidermal atrophy, premature skin barrier formation, eye abnormalities, and alopecia. Am J Pathol, 171(3), 846-60. eScholarID:107488 | PMID:17675581 | DOI:10.2353/ajpath.2007.060991
  • Schmelz, M. & Paus, R (2007). Opioids and the skin: "itchy" perspectives beyond analgesia and abuse. J Invest Dermatol, 127(6), 1287-9. eScholarID:107484 | PMID:17502859 | DOI:10.1038/sj.jid.5700634
  • Slominski, A., Wortsman, J., Tuckey, R. & Paus, R (2007). Differential expression of HPA axis homolog in the skin. Mol Cell Endocrinol, 265-266, 143-9. eScholarID:107459 | PMID:17197073 | DOI:10.1016/j.mce.2006.12.012
  • Telek, A., Bíró, T., Bodó, E., Tóth, B., Borbíró, I., Kunos, G. & Paus, R (2007). Inhibition of human hair follicle growth by endo- and exocannabinoids. FASEB J, 21(13), 3534-41. eScholarID:107473 | PMID:17567570 | DOI:10.1096/fj.06-7689com
  • Tiede, S., Kloepper, J., Whiting, D. & Paus, R (2007). The 'follicular trochanter': an epithelial compartment of the human hair follicle bulge region in need of further characterization. Br J Dermatol, 157(5), 1013-6. eScholarID:107489 | PMID:17714535 | DOI:10.1111/j.1365-2133.2007.08138.x
  • Walz, M., Kellermann, S., Bylaite, M., Andrée, B., Rüther, U., Paus, R., Kloepper, J., Reifenberger, J. & Ruzicka, T (2007). Expression of the human Cathepsin L inhibitor hurpin in mice: skin alterations and increased carcinogenesis. Exp Dermatol, 16(9), 715-23. eScholarID:107462 | PMID:17697143 | DOI:10.1111/j.1600-0625.2007.00579.x

2006

  • Adly, M., Assaf, H., Hussein, M. & Paus, R (2006). Analysis of the expression pattern of glial cell line-derived neurotrophic factor, neurturin, their cognate receptors GFRalpha-1 and GFRalpha-2, and a common signal transduction element c-Ret in the human scalp skin. J Cutan Pathol, 33(12), 799-808. eScholarID:107457 | PMID:17177940 | DOI:10.1111/j.1600-0560.2006.00561.x
  • Arck, P. & Paus, R (2006). From the brain-skin connection: the neuroendocrine-immune misalliance of stress and itch. Neuroimmunomodulation, 13(5-6), 347-56. eScholarID:107463 | PMID:17709957 | DOI:10.1159/000104863
  • Botchkarev, V., Yaar, M., Peters, E., Raychaudhuri, S., Botchkareva, N., Marconi, A., Raychaudhuri, S., Paus, R. & Pincelli, C (2006). Neurotrophins in skin biology and pathology. J Invest Dermatol, 126(8), 1719-27. eScholarID:107482 | PMID:16845411 | DOI:10.1038/sj.jid.5700270
  • Braun, S., Krampert, M., Bodó, E., Kümin, A., Born-Berclaz, C., Paus, R. & Werner, S (2006). Keratinocyte growth factor protects epidermis and hair follicles from cell death induced by UV irradiation, chemotherapeutic or cytotoxic agents. J Cell Sci, 119(Pt 23), 4841-9. eScholarID:107472 | PMID:17090603 | DOI:10.1242/jcs.03259
  • Budagian, V., Bulanova, E., Paus, R. & Bulfone-Paus, S (2006). IL-15/IL-15 receptor biology: a guided tour through an expanding universe. Cytokine Growth Factor Rev, 17(4), 259-80. eScholarID:107471 | PMID:16815076 | DOI:10.1016/j.cytogfr.2006.05.001
  • Foitzik, K., Krause, K., Conrad, F., Nakamura, M., Funk, W. & Paus, R (2006). Human scalp hair follicles are both a target and a source of prolactin, which serves as an autocrine and/or paracrine promoter of apoptosis-driven hair follicle regression. Am J Pathol, 168(3), 748-56. eScholarID:107468 | PMID:16507890 | DOI:10.2353/ajpath.2006.050468
  • Hiroi, A., Ito, T., Seo, N., Uede, K., Yoshimasu, T., Ito, M., Nakamura, K., Ito, N., Paus, R. & Furukawa, F (2006). Male New Zealand Black/KN mice: a novel model for autoimmune-induced permanent alopecia? Br J Dermatol, 155(2), 437-45. eScholarID:107477 | PMID:16882186 | DOI:10.1111/j.1365-2133.2006.07204.x
  • Kruse, C., Bodó, E., Petschnik, A., Danner, S., Tiede, S. & Paus, R (2006). Towards the development of a pragmatic technique for isolating and differentiating nestin-positive cells from human scalp skin into neuronal and glial cell populations: generating neurons from human skin? Exp Dermatol, 15(10), 794-800. eScholarID:107492 | PMID:16984261 | DOI:10.1111/j.1600-0625.2006.00471.x
  • Ohnemus, U., Uenalan, M., Inzunza, J., Gustafsson, J. & Paus, R (2006). The hair follicle as an estrogen target and source. Endocr Rev, 27(6), 677-706. eScholarID:107490 | PMID:16877675 | DOI:10.1210/er.2006-0020
  • Paus, R., Schmelz, M., Bíró, T. & Steinhoff, M (2006). Frontiers in pruritus research: scratching the brain for more effective itch therapy. J Clin Invest, 116(5), 1174-86. eScholarID:107464 | PMID:16670758 | DOI:10.1172/JCI28553
  • Peters, E., Ericson, M., Hosoi, J., Seiffert, K., Hordinsky, M., Ansel, J., Paus, R. & Scholzen, T (2006). Neuropeptide control mechanisms in cutaneous biology: physiological and clinical significance. J Invest Dermatol, 126(9), 1937-47. eScholarID:107481 | PMID:16912691 | DOI:10.1038/sj.jid.5700429
  • Peters, E., Stieglitz, M., Liezman, C., Overall, R., Nakamura, M., Hagen, E., Klapp, B., Arck, P. & Paus, R (2006). p75 Neurotrophin Receptor-Mediated Signaling Promotes Human Hair Follicle Regression (Catagen). Am J Pathol, 168(1), 221-34. eScholarID:107487 | PMID:16400025 | DOI:10.2353/ajpath.2006.050163
  • Plonka, P., Handjiski, B., Michalczyk, D., Popik, M. & Paus, R (2006). Oral zinc sulphate causes murine hair hypopigmentation and is a potent inhibitor of eumelanogenesis in vivo. Br J Dermatol, 155(1), 39-49. eScholarID:107485 | PMID:16792750 | DOI:10.1111/j.1365-2133.2006.07376.x
  • Schmidt-Ullrich, R., Tobin, D., Lenhard, D., Schneider, P., Paus, R. & Scheidereit, C (2006). NF-kappaB transmits Eda A1/EdaR signalling to activate Shh and cyclin D1 expression, and controls post-initiation hair placode down growth. Development, 133(6), 1045-57. eScholarID:107483 | PMID:16481354 | DOI:10.1242/dev.02278
  • Tiede, S. & Paus, R (2006). Lhx2--decisive role in epithelial stem cell maintenance, or just the "tip of the iceberg"? Bioessays, 28(12), 1157-60. eScholarID:107474 | PMID:17117482 | DOI:10.1002/bies.20506
  • Weller, K., Foitzik, K., Paus, R., Syska, W. & Maurer, M (2006). Mast cells are required for normal healing of skin wounds in mice. FASEB J, 20(13), 2366-8. eScholarID:107478 | PMID:16966487 | DOI:10.1096/fj.06-5837fje
  • Widelitz, R., Baker, R., Plikus, M., Lin, C., Maini, P., Paus, R. & Chuong, C (2006). Distinct mechanisms underlie pattern formation in the skin and skin appendages. Birth Defects Res C Embryo Today, 78(3), 280-91. eScholarID:107461 | PMID:17061271 | DOI:10.1002/bdrc.20075
  • Wu, X., Quondamatteo, F., Lefever, T., Czuchra, A., Meyer, H., Chrostek, A., Paus, R., Langbein, L. & Brakebusch, C (2006). Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin. Genes Dev, 20(5), 571-85. eScholarID:107458 | PMID:16510873 | DOI:10.1101/gad.361406